| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.124731 |
| GOLGA4 | golgin A4 | 0.0966078 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0759213 |
| SMAD3 | SMAD family member 3 | 0.0711055 |
| DSCAM | Down syndrome cell adhesion molecule | 0.066744 |
| RBM39 | RNA binding motif protein 39 | 0.0587805 |
| NAV2 | neuron navigator 2 | 0.0567048 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.056477 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0544761 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0487453 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0483393 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0473964 |
| RPS2 | ribosomal protein S2 | 0.0461752 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.045295 |
| NGLY1 | N-glycanase 1 | 0.0439013 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0425393 |
| ATP13A3 | ATPase type 13A3 | 0.0400886 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0396086 |
| VEGFA | vascular endothelial growth factor A | 0.0385328 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0378713 |
| USP34 | ubiquitin specific peptidase 34 | 0.0376913 |
| NBAS | neuroblastoma amplified sequence | 0.037569 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0368525 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0363263 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0362717 |
| CALU | calumenin | 0.0362014 |
| CLTC | clathrin, heavy chain (Hc) | 0.0361192 |
| SPAG9 | sperm associated antigen 9 | 0.0353947 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0343814 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0338045 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0334331 |
| YEATS2 | YEATS domain containing 2 | 0.032794 |
| VMP1 | vacuole membrane protein 1 | 0.0324749 |
| SRP54 | signal recognition particle 54kDa | 0.0321847 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.032126 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0320488 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0315228 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0308337 |
| LRRC49 | leucine rich repeat containing 49 | 0.0308164 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0307561 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0304573 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0302024 |
| CDK19 | cyclin-dependent kinase 19 | 0.0300805 |
| COG5 | component of oligomeric golgi complex 5 | 0.0296356 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0294712 |
| PTEN | phosphatase and tensin homolog | 0.0294661 |
| GOLT1B | golgi transport 1B | 0.0289342 |
| SETD5 | SET domain containing 5 | 0.0288551 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0284223 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.028398 |
| FNIP1 | folliculin interacting protein 1 | 0.028249 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0281446 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0277879 |
| CCNY | cyclin Y | 0.0276098 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0274699 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0273558 |
| TPR | translocated promoter region, nuclear basket protein | 0.0272364 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.027171 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0270361 |
| OFD1 | oral-facial-digital syndrome 1 | 0.026899 |
| TMEM165 | transmembrane protein 165 | 0.0266385 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0265215 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0262707 |
| FAM13A | family with sequence similarity 13, member A | 0.0261288 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0259418 |
| EFNA5 | ephrin-A5 | 0.0259355 |
| GOLGA3 | golgin A3 | 0.025684 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.025684 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0256519 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0256304 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0256152 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0256128 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0253916 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0252192 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0251168 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0249862 |
| MSN | moesin | 0.0249776 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.024956 |
| XPO1 | exportin 1 | 0.0248295 |
| POM121 | POM121 transmembrane nucleoporin | 0.0246987 |
| DMXL2 | Dmx-like 2 | 0.0246234 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0246097 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0242456 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0239238 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0238894 |
| CLINT1 | clathrin interactor 1 | 0.0238143 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0237442 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0234974 |
| CD109 | CD109 molecule | 0.0234141 |
| TMEM263 | transmembrane protein 263 | 0.023105 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0230315 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0228875 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0227724 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0226348 |
| CDCP1 | CUB domain containing protein 1 | 0.02249 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0224094 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0222149 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0221441 |
| FAM219A | family with sequence similarity 219, member A | 0.0220087 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0218943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228188 |
| FN1 | fibronectin 1 | -0.211148 |
| VIM | vimentin | -0.162527 |
| TMSB10 | thymosin beta 10 | -0.161111 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.128961 |
| HMGA2 | high mobility group AT-hook 2 | -0.108829 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0997736 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0870551 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0827334 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0805552 |
| LOX | lysyl oxidase | -0.0729478 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0714878 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0713792 |
| CDH13 | cadherin 13 | -0.0710206 |
| STC1 | stanniocalcin 1 | -0.068725 |
| FTL | ferritin, light polypeptide | -0.0673907 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0668536 |
| GLCCI1 | glucocorticoid induced 1 | -0.065356 |
| MAP1B | microtubule-associated protein 1B | -0.0598833 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0581811 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0554394 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0551039 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0547873 |
| RPLP1 | ribosomal protein, large, P1 | -0.0538905 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0514782 |
| AHNAK | AHNAK nucleoprotein | -0.0500622 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0492342 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.048245 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0474868 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0468304 |
| GPC6 | glypican 6 | -0.0454334 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0451241 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0444312 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0436817 |
| RNF213 | ring finger protein 213 | -0.043533 |
| LOC112694756 | uncharaterized LOC112694756 | -0.043494 |
| NRG1 | neuregulin 1 | -0.0432847 |
| CD44 | CD44 molecule (Indian blood group) | -0.0422112 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0419634 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0418733 |
| SYT1 | synaptotagmin I | -0.0418495 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0405365 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0403227 |
| ZNF804A | zinc finger protein 804A | -0.0397636 |
| FAM20C | family with sequence similarity 20, member C | -0.0392558 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.039094 |
| EGR1 | early growth response 1 | -0.038075 |
| DST | dystonin | -0.0379764 |
| TNNC1 | troponin C type 1 (slow) | -0.0373895 |
| CFAP20DC | CFAP20 domain containing | -0.0370866 |
| MT2A | metallothionein 2A | -0.0362242 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0361797 |
| SP100 | SP100 nuclear antigen | -0.0361284 |
| RPL35A | ribosomal protein L35a | -0.0356661 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.034994 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0348827 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0346774 |
| TGFB1 | transforming growth factor, beta 1 | -0.0345832 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0341958 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0341153 |
| INTS6 | integrator complex subunit 6 | -0.0338372 |
| AADAC | arylacetamide deacetylase | -0.03353 |
| CA12 | carbonic anhydrase XII | -0.0335193 |
| NDRG1 | N-myc downstream regulated 1 | -0.0330514 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0323779 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0322636 |
| GLIS3 | GLIS family zinc finger 3 | -0.0321274 |
| COL7A1 | collagen, type VII, alpha 1 | -0.031932 |
| S100A10 | S100 calcium binding protein A10 | -0.0316316 |
| ATG7 | autophagy related 7 | -0.0315392 |
| CLMP | CXADR-like membrane protein | -0.031496 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0314052 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0311668 |
| CDK14 | cyclin-dependent kinase 14 | -0.0310724 |
| NTN4 | netrin 4 | -0.0307789 |
| MTSS1 | metastasis suppressor 1 | -0.0306664 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0305579 |
| FBN1 | fibrillin 1 | -0.0304677 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.03038 |
| SUMF1 | sulfatase modifying factor 1 | -0.0301923 |
| NRP1 | neuropilin 1 | -0.029746 |
| PTMA | prothymosin, alpha | -0.0297147 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.029138 |
| CUX1 | cut-like homeobox 1 | -0.0291113 |
| RAI14 | retinoic acid induced 14 | -0.0291018 |
| NAV1 | neuron navigator 1 | -0.0288001 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.028659 |
| HMGA1 | high mobility group AT-hook 1 | -0.0282178 |
| PKM | pyruvate kinase, muscle | -0.0280962 |
| VCL | vinculin | -0.0280373 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0280347 |
| OSMR | oncostatin M receptor | -0.0279291 |
| S100A6 | S100 calcium binding protein A6 | -0.0276748 |
| MX2 | MX dynamin-like GTPase 2 | -0.027548 |
| PRSS23 | protease, serine, 23 | -0.0271843 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0271364 |
| NLK | nemo-like kinase | -0.0271064 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0266814 |
| TMSB4X | thymosin beta 4, X-linked | -0.0265005 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0262891 |
