| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.144992 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.108633 |
| RUNX1 | runt-related transcription factor 1 | 0.102347 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0983198 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0921802 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0848587 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0846033 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0789216 |
| EGFR | epidermal growth factor receptor | 0.0747551 |
| SPAG9 | sperm associated antigen 9 | 0.0722677 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0707658 |
| PHF3 | PHD finger protein 3 | 0.0599922 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0589788 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0549402 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0545198 |
| GPHN | gephyrin | 0.052624 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.048819 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0479488 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0476323 |
| LAMA4 | laminin, alpha 4 | 0.0475192 |
| PTMA | prothymosin, alpha | 0.0464998 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0464946 |
| SLTM | SAFB-like, transcription modulator | 0.0453107 |
| DST | dystonin | 0.0441598 |
| FNIP1 | folliculin interacting protein 1 | 0.0435128 |
| GOLGA4 | golgin A4 | 0.0432035 |
| SBF2 | SET binding factor 2 | 0.0422507 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0411647 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0410243 |
| IRS2 | insulin receptor substrate 2 | 0.0404603 |
| OXR1 | oxidation resistance 1 | 0.039446 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0391619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0388628 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0374662 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0368846 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.034968 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0343415 |
| MATR3 | matrin 3 | 0.0329779 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0325425 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.032461 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0320941 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0320592 |
| SYT1 | synaptotagmin I | 0.0310043 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0305619 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0302165 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0298586 |
| FBXO11 | F-box protein 11 | 0.0290895 |
| ZNF207 | zinc finger protein 207 | 0.028152 |
| PTEN | phosphatase and tensin homolog | 0.0278614 |
| RBM39 | RNA binding motif protein 39 | 0.0278586 |
| RAD51B | RAD51 paralog B | 0.0274112 |
| NKTR | natural killer cell triggering receptor | 0.0263878 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0263591 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.024891 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0245114 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0239389 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0235938 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0235802 |
| OGA | O-GlcNAcase | 0.0234131 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0228157 |
| ANXA2 | annexin A2 | 0.0225577 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0223699 |
| FRY | furry homolog (Drosophila) | 0.0223345 |
| TPD52 | tumor protein D52 | 0.0221609 |
| STC1 | stanniocalcin 1 | 0.0220125 |
| VIM | vimentin | 0.0216778 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0215627 |
| CLTC | clathrin, heavy chain (Hc) | 0.0211989 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0201533 |
| DSPP | dentin sialophosphoprotein | 0.0194829 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0190271 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0188657 |
| NF1 | neurofibromin 1 | 0.0181655 |
| EXOC4 | exocyst complex component 4 | 0.0180883 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0179449 |
| INHBA | inhibin, beta A | 0.0175982 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0170612 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0169983 |
| TMSB10 | thymosin beta 10 | 0.0167923 |
| PTK2 | protein tyrosine kinase 2 | 0.0165154 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0163598 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0163387 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0160353 |
| ACTG1 | actin gamma 1 | 0.016017 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0158714 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0154258 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.015293 |
| RTN4 | reticulon 4 | 0.0152799 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0152272 |
| RPS6 | ribosomal protein S6 | 0.0142828 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0141778 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0138766 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0134907 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0134503 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0132373 |
| CEP350 | centrosomal protein 350kDa | 0.012827 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0127893 |
| MCL1 | myeloid cell leukemia 1 | 0.0121468 |
| CALD1 | caldesmon 1 | 0.0119891 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0116572 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.209122 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.144382 |
| LAMB3 | laminin, beta 3 | -0.101183 |
| ATOSA | atos homolog A | -0.0956191 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0946842 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0881527 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0822796 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0797573 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0777725 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0754128 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0751861 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0744949 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0734035 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0693747 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0686787 |
| AHNAK | AHNAK nucleoprotein | -0.0683375 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0681551 |
| KIAA1217 | KIAA1217 | -0.0673925 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0667075 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0655346 |
| PARD3 | par-3 family cell polarity regulator | -0.0642722 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0636194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0634924 |
| LMO7 | LIM domain 7 | -0.0617999 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0602284 |
| ABHD17C | abhydrolase domain containing 17C | -0.0601999 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0581869 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0581819 |
| RIGI | RNA sensor RIG-I | -0.0569464 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0549827 |
| DENND1A | DENN/MADD domain containing 1A | -0.0539441 |
| CMIP | c-Maf inducing protein | -0.0519136 |
| NEBL | nebulette | -0.0517545 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0511304 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0508851 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0504565 |
| MUC16 | mucin 16, cell surface associated | -0.0493813 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0493175 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0491051 |
| DSG2 | desmoglein 2 | -0.0490146 |
| KRT17 | keratin 17, type I | -0.0484053 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0476439 |
| RIOK3 | RIO kinase 3 | -0.0474996 |
| TXNRD1 | thioredoxin reductase 1 | -0.0459567 |
| MYO1E | myosin IE | -0.0458867 |
| FAM107B | family with sequence similarity 107, member B | -0.0455181 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0446062 |
| FOXO3 | forkhead box O3 | -0.0434352 |
| SVIL | supervillin | -0.0413502 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0410965 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0391937 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0368062 |
| SNX9 | sorting nexin 9 | -0.0362421 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0358566 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0341149 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0334339 |
| POTEF | POTE ankyrin domain family, member F | -0.0332579 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.032763 |
| ZNF638 | zinc finger protein 638 | -0.0324369 |
| SMYD3 | SET and MYND domain containing 3 | -0.0323372 |
| RORA | RAR-related orphan receptor A | -0.032057 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0318366 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0312275 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0311693 |
| NBEA | neurobeachin | -0.0311491 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0310703 |
| EZR | ezrin | -0.0307732 |
| GOLGB1 | golgin B1 | -0.0302205 |
| AUTS2 | autism susceptibility candidate 2 | -0.0296461 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.028442 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0271722 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270375 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0267248 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0261839 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0261242 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0260077 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0254248 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.023256 |
| SEC24D | SEC24 family member D | -0.0230671 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0228379 |
| FAM13A | family with sequence similarity 13, member A | -0.0223732 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0221592 |
| BPTF | bromodomain PHD finger transcription factor | -0.0221026 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0214858 |
| PRELID2 | PRELI domain containing 2 | -0.0207411 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0202598 |
| SETD5 | SET domain containing 5 | -0.0201408 |
| MYOF | myoferlin | -0.0195206 |
| ZNF292 | zinc finger protein 292 | -0.0192294 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0189145 |
| VCL | vinculin | -0.0188649 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0186556 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0183629 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0178967 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0176008 |
| TJP1 | tight junction protein 1 | -0.0174701 |
| PHF21A | PHD finger protein 21A | -0.0168887 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0167199 |
| PDE10A | phosphodiesterase 10A | -0.0165639 |
| MYO6 | myosin VI | -0.0164221 |
