| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.116955 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.108668 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104856 |
| COPA | coatomer protein complex, subunit alpha | 0.0788176 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0773082 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0717235 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0636262 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0630005 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0618828 |
| TPM3 | tropomyosin 3 | 0.0579864 |
| GOLGB1 | golgin B1 | 0.0551119 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0547815 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0519863 |
| POTEF | POTE ankyrin domain family, member F | 0.0517562 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0507016 |
| PYGL | phosphorylase, glycogen, liver | 0.0483876 |
| GOLGA4 | golgin A4 | 0.0450516 |
| ANO6 | anoctamin 6 | 0.0438504 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0417395 |
| HELZ | helicase with zinc finger | 0.0412719 |
| MSN | moesin | 0.0396808 |
| BRD2 | bromodomain containing 2 | 0.0395796 |
| BBX | bobby sox homolog (Drosophila) | 0.0392676 |
| CLTC | clathrin, heavy chain (Hc) | 0.0390047 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0389364 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0388316 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0387012 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0367634 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0356562 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0348865 |
| CANX | calnexin | 0.0346972 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0341451 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0341345 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0325778 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0318098 |
| CCNL1 | cyclin L1 | 0.0314827 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0314301 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0314109 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.029935 |
| SRP54 | signal recognition particle 54kDa | 0.0297727 |
| IGF2 | insulin-like growth factor 2 | 0.0294015 |
| DSPP | dentin sialophosphoprotein | 0.0291737 |
| FNIP1 | folliculin interacting protein 1 | 0.0288758 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0287134 |
| USP34 | ubiquitin specific peptidase 34 | 0.0273037 |
| NLGN1 | neuroligin 1 | 0.0271347 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0271159 |
| PCBP2 | poly(rC) binding protein 2 | 0.0263272 |
| CTTN | cortactin | 0.0262909 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0260884 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0258803 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0255269 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0255001 |
| ATXN1 | ataxin 1 | 0.0253977 |
| KMT5B | lysine methyltransferase 5B | 0.025233 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0251002 |
| XPO1 | exportin 1 | 0.0249347 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.024825 |
| PRELID2 | PRELI domain containing 2 | 0.0245925 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0244988 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0244966 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0242603 |
| TMF1 | TATA element modulatory factor 1 | 0.024126 |
| MYOF | myoferlin | 0.0235982 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0232959 |
| GOLT1B | golgi transport 1B | 0.0232015 |
| SRPK1 | SRSF protein kinase 1 | 0.0228339 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0227228 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.022236 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0220616 |
| NUP58 | nucleoporin 58 | 0.0220073 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0219079 |
| SET | SET nuclear proto-oncogene | 0.0216543 |
| NOTCH2 | notch 2 | 0.0215845 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0214784 |
| JAK1 | Janus kinase 1 | 0.0214072 |
| NRDC | nardilysin convertase | 0.0213411 |
| GPATCH2L | G patch domain containing 2-like | 0.0211574 |
| RLF | rearranged L-myc fusion | 0.020962 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0207383 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0206745 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0205837 |
| NDRG1 | N-myc downstream regulated 1 | 0.0204232 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0204061 |
| TPX2 | TPX2, microtubule-associated | 0.0203501 |
| JMJD1C | jumonji domain containing 1C | 0.0202531 |
| MYO6 | myosin VI | 0.0200649 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0199414 |
| EHBP1 | EH domain binding protein 1 | 0.0197882 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0197788 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0197067 |
| UBC | ubiquitin C | 0.0196731 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.019614 |
| SUCO | SUN domain containing ossification factor | 0.0196138 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0195534 |
| BRD4 | bromodomain containing 4 | 0.0194936 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0194749 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0194639 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0194308 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0193308 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.146056 |
| GRAMD1B | GRAM domain containing 1B | -0.137493 |
| VIM | vimentin | -0.120538 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102048 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0936313 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0865058 |
| RPS21 | ribosomal protein S21 | -0.0840217 |
| RPL23 | ribosomal protein L23 | -0.077465 |
| RPL35A | ribosomal protein L35a | -0.0702846 |
| PTMA | prothymosin, alpha | -0.0679727 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0676104 |
| RPS8 | ribosomal protein S8 | -0.0659028 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0647496 |
| RPL19 | ribosomal protein L19 | -0.057742 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0568133 |
| RPLP1 | ribosomal protein, large, P1 | -0.0559944 |
| RPL12 | ribosomal protein L12 | -0.054954 |
| RPL26 | ribosomal protein L26 | -0.0518725 |
| RPS27 | ribosomal protein S27 | -0.0504077 |
| OSMR | oncostatin M receptor | -0.0494588 |
| TXNRD1 | thioredoxin reductase 1 | -0.0478612 |
| RPLP2 | ribosomal protein, large, P2 | -0.0459919 |
| RPL34 | ribosomal protein L34 | -0.0452964 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0452516 |
| SLC38A2 | solute carrier family 38, member 2 | -0.04415 |
| CDK17 | cyclin-dependent kinase 17 | -0.0432295 |
| KLF6 | Kruppel-like factor 6 | -0.0426431 |
| AHNAK | AHNAK nucleoprotein | -0.0425471 |
| RPS19 | ribosomal protein S19 | -0.0419786 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0409845 |
| RPS3 | ribosomal protein S3 | -0.0406576 |
| RPS24 | ribosomal protein S24 | -0.04046 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0402951 |
| RPS27A | ribosomal protein S27a | -0.040268 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0402045 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0398763 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0398679 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0398342 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0394794 |
| ATP11A | ATPase, class VI, type 11A | -0.0393395 |
| RPS4X | ribosomal protein S4, X-linked | -0.0385693 |
| RPL11 | ribosomal protein L11 | -0.0373935 |
| FUS | FUS RNA binding protein | -0.0367973 |
| RPS15 | ribosomal protein S15 | -0.0367108 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0363742 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0358583 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0358079 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0356411 |
| RPL37 | ribosomal protein L37 | -0.0353941 |
| RPS29 | ribosomal protein S29 | -0.0353693 |
| RPS12 | ribosomal protein S12 | -0.0351649 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0349664 |
| RPL37A | ribosomal protein L37a | -0.0346667 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0344133 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0341616 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0335253 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0333836 |
| RPS6 | ribosomal protein S6 | -0.0328332 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0322324 |
| RPL32 | ribosomal protein L32 | -0.0318635 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0312599 |
| RPL35 | ribosomal protein L35 | -0.0310478 |
| FMNL2 | formin-like 2 | -0.0310006 |
| DENND5B | DENN/MADD domain containing 5B | -0.0309771 |
| FBXO11 | F-box protein 11 | -0.030958 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0307962 |
| ACTG1 | actin gamma 1 | -0.0305411 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0303864 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0302738 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0300239 |
| GNAS | GNAS complex locus | -0.0297185 |
| RPL36 | ribosomal protein L36 | -0.0296109 |
| RPS17 | ribosomal protein S17 | -0.0294183 |
| RPL38 | ribosomal protein L38 | -0.029171 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.028888 |
| RPLP0 | ribosomal protein, large, P0 | -0.0288468 |
| PDE10A | phosphodiesterase 10A | -0.0286665 |
| RPL5 | ribosomal protein L5 | -0.0284736 |
| RPL28 | ribosomal protein L28 | -0.0283184 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0275879 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0275734 |
| RPL31 | ribosomal protein L31 | -0.026682 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0266606 |
| RPL8 | ribosomal protein L8 | -0.026659 |
| ZFR | zinc finger RNA binding protein | -0.0262871 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.026221 |
| UBTF | upstream binding transcription factor, RNA polymerase I | -0.0256989 |
| RPL18 | ribosomal protein L18 | -0.0256728 |
| RTN4 | reticulon 4 | -0.0253131 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0251812 |
| RPL9 | ribosomal protein L9 | -0.0249796 |
| RPL27 | ribosomal protein L27 | -0.0249497 |
| TPI1 | triosephosphate isomerase 1 | -0.0248141 |
| RPS23 | ribosomal protein S23 | -0.0247861 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0247165 |
| PFN1 | profilin 1 | -0.0245919 |
| RPS20 | ribosomal protein S20 | -0.0245756 |
| RAD51B | RAD51 paralog B | -0.0244232 |
| RPS14 | ribosomal protein S14 | -0.0243884 |
| PLSCR1 | phospholipid scramblase 1 | -0.0243577 |
