| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.129093 |
| COL11A1 | collagen, type XI, alpha 1 | 0.1243 |
| TSC22D2 | TSC22 domain family, member 2 | 0.120155 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.11553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114015 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0796085 |
| PHIP | pleckstrin homology domain interacting protein | 0.0769042 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0736736 |
| DST | dystonin | 0.0726272 |
| SRP54 | signal recognition particle 54kDa | 0.0706577 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0697349 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0635008 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0629733 |
| SNX6 | sorting nexin 6 | 0.0626899 |
| FBXO11 | F-box protein 11 | 0.0624132 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0620075 |
| RPS6 | ribosomal protein S6 | 0.060115 |
| PTMA | prothymosin, alpha | 0.0592306 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0586796 |
| POTEF | POTE ankyrin domain family, member F | 0.0578131 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0577924 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0553073 |
| CALR | calreticulin | 0.0547653 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.053942 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0535785 |
| PUM1 | pumilio RNA-binding family member 1 | 0.052613 |
| PLPP1 | phospholipid phosphatase 1 | 0.0493651 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0481082 |
| PGK1 | phosphoglycerate kinase 1 | 0.0481038 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0468858 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0468774 |
| SETD5 | SET domain containing 5 | 0.046707 |
| NCKAP1 | NCK-associated protein 1 | 0.0464104 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0459601 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.045873 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0453755 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.043459 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.043124 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0428506 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.042798 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0416615 |
| PRTG | protogenin | 0.0411156 |
| MED13L | mediator complex subunit 13-like | 0.0410996 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0406756 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0405898 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0405367 |
| RPS12 | ribosomal protein S12 | 0.0404959 |
| VIM | vimentin | 0.0404275 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0402544 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0402137 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0393544 |
| RPS2 | ribosomal protein S2 | 0.0392738 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.0389988 |
| PFN1 | profilin 1 | 0.0385836 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0379447 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0376565 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0375099 |
| PEG10 | paternally expressed 10 | 0.0373055 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0370161 |
| APP | amyloid beta (A4) precursor protein | 0.0362992 |
| RASAL2 | RAS protein activator like 2 | 0.0362459 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0360962 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0351541 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0345274 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0341616 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0341077 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0340376 |
| LDHA | lactate dehydrogenase A | 0.0340208 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0338591 |
| CLTC | clathrin, heavy chain (Hc) | 0.033717 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.033431 |
| PDS5B | PDS5 cohesin associated factor B | 0.0333279 |
| RBM27 | RNA binding motif protein 27 | 0.0331507 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0330761 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.033001 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0328947 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0328068 |
| CALU | calumenin | 0.0327719 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0327459 |
| SET | SET nuclear proto-oncogene | 0.0324812 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0323088 |
| ATXN2 | ataxin 2 | 0.0317172 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.031667 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0315512 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0312901 |
| ENAH | enabled homolog (Drosophila) | 0.0311099 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0309786 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0306226 |
| YBX1 | Y box binding protein 1 | 0.0304679 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.030415 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0301245 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0300668 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0299064 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0298485 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0295611 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0293949 |
| RHEB | Ras homolog enriched in brain | 0.02936 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0290363 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0289562 |
| IPO7 | importin 7 | 0.0289235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0584306 |
| THBS1 | thrombospondin 1 | -0.0522217 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0452142 |
| HDAC9 | histone deacetylase 9 | -0.0450482 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0412727 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.039212 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0385658 |
| GPC3 | glypican 3 | -0.0335877 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0295757 |
| SYT1 | synaptotagmin I | -0.0291535 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0258815 |
| SMYD3 | SET and MYND domain containing 3 | -0.0257665 |
| UPP1 | uridine phosphorylase 1 | -0.0246351 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0240194 |
| CADM2 | cell adhesion molecule 2 | -0.0232174 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0224428 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0212159 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0205597 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0204978 |
| VGLL3 | vestigial-like family member 3 | -0.020384 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0196679 |
| CDYL | chromodomain protein, Y-like | -0.0195221 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0189914 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0188203 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0187695 |
| ANKRD33B | ankyrin repeat domain 33B | -0.018488 |
| ZNF385D | zinc finger protein 385D | -0.0182991 |
| NFIA | nuclear factor I/A | -0.0182292 |
| MYL12B | myosin, light chain 12B, regulatory | -0.01815 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0180881 |
| ACTG1 | actin gamma 1 | -0.0177737 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.0173116 |
| NTM | neurotrimin | -0.0172476 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0169117 |
| CBX3 | chromobox homolog 3 | -0.0168059 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.016414 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0161413 |
| MACROD2 | MACRO domain containing 2 | -0.0160574 |
| SHROOM3 | shroom family member 3 | -0.0159473 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0158581 |
| KIAA1328 | KIAA1328 | -0.0156576 |
| RNASE7 | ribonuclease, RNase A family, 7 | -0.0150893 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0150699 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0148091 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | -0.0146671 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0146526 |
| AUTS2 | autism susceptibility candidate 2 | -0.0146271 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0144182 |
| CMTR1 | cap methyltransferase 1 | -0.0142989 |
| PDGFC | platelet derived growth factor C | -0.0141252 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0139504 |
| RASA2 | RAS p21 protein activator 2 | -0.0138498 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.0137019 |
| TUBA1C | tubulin, alpha 1c | -0.0135594 |
| IRAK1BP1 | interleukin-1 receptor-associated kinase 1 binding protein 1 | -0.0134407 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0133627 |
| EXOC4 | exocyst complex component 4 | -0.0131197 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0129613 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0129592 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0129524 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.012928 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0129072 |
| PCNX4 | pecanex 4 | -0.012902 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.012832 |
| HMCN1 | hemicentin 1 | -0.0127882 |
| AK8 | adenylate kinase 8 | -0.0126496 |
| MEF2C | myocyte enhancer factor 2C | -0.0126247 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.0125089 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0124118 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0123863 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0123526 |
| ZNF608 | zinc finger protein 608 | -0.0122397 |
| COPS6 | COP9 signalosome subunit 6 | -0.0122253 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0122062 |
| ACER3 | alkaline ceramidase 3 | -0.0121891 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0121727 |
| IREB2 | iron-responsive element binding protein 2 | -0.0120281 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0119703 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0119339 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0119111 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | -0.0117439 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0116233 |
| IKBIP | IKBKB interacting protein | -0.0114415 |
| ENTREP1 | endosomal transmembrane epsin interactor 1 | -0.0114371 |
| POMP | proteasome maturation protein | -0.0114225 |
| FKBP3 | FK506 binding protein 3, 25kDa | -0.0113697 |
| MYO9A | myosin IXA | -0.0113632 |
| PDCD5 | programmed cell death 5 | -0.0112974 |
| INTS8 | integrator complex subunit 8 | -0.0112943 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0112523 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0112495 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0112457 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0112347 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0112215 |
| NF1 | neurofibromin 1 | -0.0111852 |
| RLIM | ring finger protein, LIM domain interacting | -0.0111758 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.0111708 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0109888 |
| MROH8 | maestro heat-like repeat family member 8 | -0.0109647 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | -0.0109371 |
