| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0842416 |
| PGK1 | phosphoglycerate kinase 1 | 0.0832083 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0711451 |
| GOLGA4 | golgin A4 | 0.0693281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.059191 |
| ZNF292 | zinc finger protein 292 | 0.0578253 |
| STC1 | stanniocalcin 1 | 0.0547531 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0539676 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0536115 |
| RBM39 | RNA binding motif protein 39 | 0.0493584 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0472452 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0470669 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0443557 |
| NDRG1 | N-myc downstream regulated 1 | 0.0434638 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0425541 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0422029 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.041901 |
| SETD5 | SET domain containing 5 | 0.0389011 |
| CD109 | CD109 molecule | 0.0378907 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0377766 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0377712 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0377675 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0359818 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0347639 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0339647 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0339143 |
| XPO1 | exportin 1 | 0.0326396 |
| HELZ | helicase with zinc finger | 0.0323756 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0317735 |
| RLF | rearranged L-myc fusion | 0.0310499 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0291346 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0290384 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0284606 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0283694 |
| TMF1 | TATA element modulatory factor 1 | 0.0281934 |
| CENPF | centromere protein F, 350/400kDa | 0.0278317 |
| ATP13A3 | ATPase type 13A3 | 0.0277056 |
| INSIG2 | insulin induced gene 2 | 0.0275854 |
| OGA | O-GlcNAcase | 0.0275782 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0272393 |
| FAM13A | family with sequence similarity 13, member A | 0.0271989 |
| SPAG9 | sperm associated antigen 9 | 0.0265945 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0265658 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.026407 |
| TFG | TRK-fused gene | 0.0262157 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0260343 |
| ANLN | anillin, actin binding protein | 0.0258985 |
| SUCO | SUN domain containing ossification factor | 0.0253458 |
| YEATS2 | YEATS domain containing 2 | 0.0252372 |
| SRP54 | signal recognition particle 54kDa | 0.025199 |
| CALU | calumenin | 0.0250671 |
| RTN4 | reticulon 4 | 0.0248554 |
| CANX | calnexin | 0.0247339 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0244142 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.024288 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242749 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0242173 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0239946 |
| LDHA | lactate dehydrogenase A | 0.0237168 |
| CDC73 | cell division cycle 73 | 0.0235392 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.023514 |
| NUP58 | nucleoporin 58 | 0.0233936 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0233446 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0231793 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0231766 |
| TPX2 | TPX2, microtubule-associated | 0.0230378 |
| NGLY1 | N-glycanase 1 | 0.0230125 |
| COPA | coatomer protein complex, subunit alpha | 0.0227926 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0227134 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0225537 |
| QKI | QKI, KH domain containing, RNA binding | 0.0225168 |
| FMNL2 | formin-like 2 | 0.0222206 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0218642 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0218389 |
| MYOF | myoferlin | 0.0217277 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0217273 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0217173 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0214864 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0214218 |
| USP3 | ubiquitin specific peptidase 3 | 0.0214095 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0213576 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0212005 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0208391 |
| HDLBP | high density lipoprotein binding protein | 0.0208299 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0207039 |
| MORF4L2 | mortality factor 4 like 2 | 0.0207015 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0206012 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0205134 |
| RYBP | RING1 and YY1 binding protein | 0.0204107 |
| FNIP1 | folliculin interacting protein 1 | 0.0203143 |
| HMGB2 | high mobility group box 2 | 0.0202921 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0202878 |
| MEF2A | myocyte enhancer factor 2A | 0.020216 |
| NOP58 | NOP58 ribonucleoprotein | 0.0202124 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0202012 |
| FAM162A | family with sequence similarity 162, member A | 0.0201612 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0201445 |
| PUM2 | pumilio RNA-binding family member 2 | 0.020054 |
| SEC24D | SEC24 family member D | 0.0200139 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0198367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.0893761 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0810052 |
| VIM | vimentin | -0.078642 |
| TMSB10 | thymosin beta 10 | -0.0649355 |
| COL1A1 | collagen, type I, alpha 1 | -0.0595627 |
| B2M | beta-2-microglobulin | -0.0545157 |
| MT2A | metallothionein 2A | -0.048561 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0462219 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0443638 |
| FTL | ferritin, light polypeptide | -0.0441465 |
| COL1A2 | collagen, type I, alpha 2 | -0.0434117 |
| CDH13 | cadherin 13 | -0.0378376 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0371756 |
| HLA-A | major histocompatibility complex, class I, A | -0.0371333 |
| EGR1 | early growth response 1 | -0.0331433 |
| NAV1 | neuron navigator 1 | -0.0316003 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0309433 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0303818 |
| RPL35A | ribosomal protein L35a | -0.0287846 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0281196 |
| FRMD4A | FERM domain containing 4A | -0.0272295 |
| NRP1 | neuropilin 1 | -0.0270995 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0255251 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0255118 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0250642 |
| GLIS3 | GLIS family zinc finger 3 | -0.0229042 |
| RPLP1 | ribosomal protein, large, P1 | -0.0227497 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0216821 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0214589 |
| HLA-C | major histocompatibility complex, class I, C | -0.0214401 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0213426 |
| SP100 | SP100 nuclear antigen | -0.0202983 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0198055 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0197738 |
| RPS19 | ribosomal protein S19 | -0.0196992 |
| POTEF | POTE ankyrin domain family, member F | -0.0192697 |
| INHBA | inhibin, beta A | -0.0187587 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0187466 |
| FHIT | fragile histidine triad | -0.0181209 |
| CST3 | cystatin C | -0.0180384 |
| IFI44L | interferon-induced protein 44-like | -0.0179128 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0177822 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0172806 |
| RIGI | RNA sensor RIG-I | -0.0172732 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0172568 |
| COL5A3 | collagen, type V, alpha 3 | -0.0168681 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0162728 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0160926 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0156875 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.015646 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0149551 |
| HDAC9 | histone deacetylase 9 | -0.0147996 |
| S100A6 | S100 calcium binding protein A6 | -0.0147154 |
| ITGA11 | integrin, alpha 11 | -0.014518 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0144755 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0144042 |
| S100A9 | S100 calcium binding protein A9 | -0.0144028 |
| IL1B | interleukin 1, beta | -0.0142796 |
| C1R | complement component 1, r subcomponent | -0.0140174 |
| RPL31 | ribosomal protein L31 | -0.0138476 |
| COL5A1 | collagen, type V, alpha 1 | -0.0137287 |
| RPS17 | ribosomal protein S17 | -0.0136322 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0136195 |
| RPS21 | ribosomal protein S21 | -0.0135645 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0134743 |
| RPL28 | ribosomal protein L28 | -0.0134582 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0132049 |
| TNS3 | tensin 3 | -0.0130432 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0130193 |
| RPL23 | ribosomal protein L23 | -0.0130102 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0129545 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0129275 |
| S100A11 | S100 calcium binding protein A11 | -0.0128843 |
| MMP2 | matrix metallopeptidase 2 | -0.0127767 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0127296 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0126864 |
| PLSCR1 | phospholipid scramblase 1 | -0.0126635 |
| TMEM178B | transmembrane protein 178B | -0.0124382 |
| ACTG1 | actin gamma 1 | -0.0123577 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0123306 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0122913 |
| PFN1 | profilin 1 | -0.0121727 |
| TNNC1 | troponin C type 1 (slow) | -0.0120477 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0119766 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0118703 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0117164 |
| RNF213 | ring finger protein 213 | -0.0116714 |
| MX1 | MX dynamin-like GTPase 1 | -0.0115188 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0113339 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0112905 |
| SUMF1 | sulfatase modifying factor 1 | -0.011234 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0111717 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0110323 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0110005 |
| RPL9 | ribosomal protein L9 | -0.010984 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0109672 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0109316 |
| FOSL1 | FOS-like antigen 1 | -0.0109225 |
| CCND1 | cyclin D1 | -0.0107912 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0106856 |
