| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0807524 |
| RPS6 | ribosomal protein S6 | 0.0386645 |
| EGR1 | early growth response 1 | 0.0321297 |
| RPS2 | ribosomal protein S2 | 0.0278857 |
| FTL | ferritin, light polypeptide | 0.0271427 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0189954 |
| RPL11 | ribosomal protein L11 | 0.018088 |
| DSTN | destrin (actin depolymerizing factor) | 0.0175418 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0170094 |
| NOP58 | NOP58 ribonucleoprotein | 0.016927 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0167774 |
| CENPF | centromere protein F, 350/400kDa | 0.0161885 |
| POTEF | POTE ankyrin domain family, member F | 0.0155172 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0151268 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0150308 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.0148249 |
| RPS19 | ribosomal protein S19 | 0.0141479 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0136658 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0136185 |
| SNU13 | small nuclear ribonucleoprotein 13 | 0.0133107 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0126782 |
| TPM4 | tropomyosin 4 | 0.0125442 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0124457 |
| VEGFA | vascular endothelial growth factor A | 0.0122865 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0115489 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0115308 |
| PTMA | prothymosin, alpha | 0.0113936 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0110559 |
| HDAC9 | histone deacetylase 9 | 0.0110417 |
| NDRG1 | N-myc downstream regulated 1 | 0.0110329 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0104584 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0104376 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0103088 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0102492 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0101749 |
| TOX | thymocyte selection-associated high mobility group box | 0.010093 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00999138 |
| JAM3 | junctional adhesion molecule 3 | 0.00997574 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00965519 |
| VCL | vinculin | 0.00960228 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00956051 |
| FAM13A | family with sequence similarity 13, member A | 0.00954091 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00938144 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00918239 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.00918043 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00908114 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00898227 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00890911 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.00882949 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00877869 |
| SNX3 | sorting nexin 3 | 0.00875071 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00855742 |
| RPL21 | ribosomal protein L21 | 0.00853569 |
| PPDPFL | pancreatic progenitor cell differentiation and proliferation factor like | 0.00853145 |
| RPL7 | ribosomal protein L7 | 0.00846298 |
| CD24 | CD24 molecule | 0.00839315 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00834182 |
| FBXO41 | F-box protein 41 | 0.0083332 |
| S100A9 | S100 calcium binding protein A9 | 0.00818419 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.00816745 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.00815706 |
| RPL38 | ribosomal protein L38 | 0.00812207 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00808349 |
| COX7C | cytochrome c oxidase subunit VIIc | 0.00799227 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00788451 |
| MSN | moesin | 0.0078071 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.00770727 |
| SERF2 | small EDRK-rich factor 2 | 0.00766434 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.00764849 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00764762 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00762009 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00761875 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.00760702 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0076029 |
| HMGA1 | high mobility group AT-hook 1 | 0.00748037 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | 0.00747912 |
| ILF2 | interleukin enhancer binding factor 2 | 0.00743843 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.00735827 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.00727771 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00717862 |
| SMIM44 | small integral membrane protein 44 | 0.00717821 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00717052 |
| ATF4 | activating transcription factor 4 | 0.00715023 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00712924 |
| CST3 | cystatin C | 0.00710693 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.00707631 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00706911 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.00706274 |
| RGS2 | regulator of G-protein signaling 2 | 0.00706142 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0070548 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00704597 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.00703406 |
| NPAS4 | neuronal PAS domain protein 4 | 0.00701864 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 | 0.00699611 |
| GNAS | GNAS complex locus | 0.00699545 |
| RPS16 | ribosomal protein S16 | 0.00696101 |
| MALT1 | MALT1 paracaspase | 0.00696054 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00693284 |
| PNN | pinin, desmosome associated protein | 0.00693263 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | 0.00690908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.129168 |
| ENO1 | enolase 1, (alpha) | -0.12102 |
| VGF | VGF nerve growth factor inducible | -0.110342 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0741019 |
| TENM1 | teneurin transmembrane protein 1 | -0.0720426 |
| RPS27A | ribosomal protein S27a | -0.0579354 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0553448 |
| UBC | ubiquitin C | -0.0546402 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0533373 |
| GPC6 | glypican 6 | -0.0488168 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0468023 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.045922 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0452159 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0438798 |
| SMYD3 | SET and MYND domain containing 3 | -0.0437807 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0413713 |
| NRG1 | neuregulin 1 | -0.04009 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0400552 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0368066 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0358298 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0355302 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0334483 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0334308 |
| MCL1 | myeloid cell leukemia 1 | -0.0328565 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0310487 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0307847 |
| STC1 | stanniocalcin 1 | -0.0293323 |
| PEG10 | paternally expressed 10 | -0.02888 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0283452 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0278978 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0262047 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0253209 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0251367 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0250436 |
| NCKAP5 | NCK-associated protein 5 | -0.0248999 |
| CHGB | chromogranin B | -0.0247098 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0237134 |
| INHBA | inhibin, beta A | -0.0236157 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0235385 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0234431 |
| ASPH | aspartate beta-hydroxylase | -0.0233116 |
| KIF26B | kinesin family member 26B | -0.0231285 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0230269 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0226336 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0224997 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0223416 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0221802 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0221691 |
| PCBP3 | poly(rC) binding protein 3 | -0.0220824 |
| FGF14 | fibroblast growth factor 14 | -0.0220387 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0219661 |
| RPL23 | ribosomal protein L23 | -0.0219191 |
| RORA | RAR-related orphan receptor A | -0.0218716 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0214921 |
| RTN4 | reticulon 4 | -0.0213895 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0209761 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0209653 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0207968 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0207832 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0207749 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0207619 |
| NBAS | neuroblastoma amplified sequence | -0.020554 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0205429 |
| RPL4 | ribosomal protein L4 | -0.0205406 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0204527 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.0204347 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0202183 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0201914 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0200711 |
| PCBP2 | poly(rC) binding protein 2 | -0.0199271 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0198798 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0197861 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0197056 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0195065 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0194696 |
| APP | amyloid beta (A4) precursor protein | -0.0194471 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0193574 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0193435 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0192302 |
| PGK1 | phosphoglycerate kinase 1 | -0.0191374 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0190229 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0190144 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0189945 |
| EFNA5 | ephrin-A5 | -0.0186664 |
| CANX | calnexin | -0.0184569 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0183707 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0183615 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0182608 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0180109 |
| PTK2 | protein tyrosine kinase 2 | -0.0180079 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.017744 |
| RNF144A | ring finger protein 144A | -0.0175981 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0175604 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0175108 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0174133 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.017392 |
| DST | dystonin | -0.0173312 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0172974 |
| PTCHD4 | patched domain containing 4 | -0.0171877 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0171006 |
