| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.25444 |
| GOLGA4 | golgin A4 | 0.0571502 |
| SPAG9 | sperm associated antigen 9 | 0.0466486 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0459505 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0436363 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0390582 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0378501 |
| FMNL2 | formin-like 2 | 0.0366036 |
| SETD5 | SET domain containing 5 | 0.0364648 |
| RAD51B | RAD51 paralog B | 0.0357454 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0357277 |
| CLINT1 | clathrin interactor 1 | 0.0356121 |
| LSAMP | limbic system-associated membrane protein | 0.0332066 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0331381 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.033005 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.032365 |
| CENPF | centromere protein F, 350/400kDa | 0.0321081 |
| MSN | moesin | 0.0319754 |
| HELZ | helicase with zinc finger | 0.0309633 |
| JMJD1C | jumonji domain containing 1C | 0.0300861 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0288983 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0281376 |
| SBF2 | SET binding factor 2 | 0.0275524 |
| PTMA | prothymosin, alpha | 0.0273642 |
| CADM1 | cell adhesion molecule 1 | 0.0269967 |
| SFTPA2 | surfactant protein A2 | 0.0268651 |
| SEC24A | SEC24 family member A | 0.0264584 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0263785 |
| POTEF | POTE ankyrin domain family, member F | 0.0256156 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.02561 |
| YEATS2 | YEATS domain containing 2 | 0.025576 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0253407 |
| RPS2 | ribosomal protein S2 | 0.0252292 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0252108 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0250292 |
| NLGN1 | neuroligin 1 | 0.024772 |
| TENM1 | teneurin transmembrane protein 1 | 0.0244812 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0244245 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0243676 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.024221 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0242197 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0233484 |
| ANKRD11 | ankyrin repeat domain 11 | 0.023177 |
| CDK6 | cyclin-dependent kinase 6 | 0.0230499 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0229601 |
| MMP12 | matrix metallopeptidase 12 | 0.0228873 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0227948 |
| NOP58 | NOP58 ribonucleoprotein | 0.0225891 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.022507 |
| MSI2 | musashi RNA-binding protein 2 | 0.0223274 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0220587 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0220512 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0218401 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0216299 |
| MATR3 | matrin 3 | 0.0215671 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0213466 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0210453 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0210173 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0209252 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0207007 |
| SNU13 | small nuclear ribonucleoprotein 13 | 0.0203323 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0199452 |
| PGK1 | phosphoglycerate kinase 1 | 0.0198376 |
| RNF145 | ring finger protein 145 | 0.0197639 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0196452 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0196415 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0195615 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0194717 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0194685 |
| QKI | QKI, KH domain containing, RNA binding | 0.0194274 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0194224 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0194114 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0192467 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0190992 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0190741 |
| CLTC | clathrin, heavy chain (Hc) | 0.0189529 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0189 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0187302 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0186822 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0186819 |
| TRIM33 | tripartite motif containing 33 | 0.0186593 |
| UBQLN1 | ubiquilin 1 | 0.0186118 |
| MLEC | malectin | 0.0184963 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0183485 |
| CEP350 | centrosomal protein 350kDa | 0.0183315 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0183112 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0181666 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0180539 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0179701 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.017831 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0177972 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0177759 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0177 |
| RPS6 | ribosomal protein S6 | 0.0175467 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0174112 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0173408 |
| FAM13A | family with sequence similarity 13, member A | 0.0172583 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0171577 |
| RRBP1 | ribosome binding protein 1 | 0.017136 |
| CDK19 | cyclin-dependent kinase 19 | 0.0169851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.198645 |
| UBC | ubiquitin C | -0.108135 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0812654 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0594494 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0526611 |
| RPS27A | ribosomal protein S27a | -0.0517 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0457324 |
| TXNRD1 | thioredoxin reductase 1 | -0.0437974 |
| SQSTM1 | sequestosome 1 | -0.0395564 |
| TMSB10 | thymosin beta 10 | -0.0390947 |
| RPS3 | ribosomal protein S3 | -0.0373178 |
| ENO1 | enolase 1, (alpha) | -0.0352444 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0347358 |
| MT2A | metallothionein 2A | -0.0342461 |
| AHNAK | AHNAK nucleoprotein | -0.033972 |
| RPL23 | ribosomal protein L23 | -0.0327341 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0315352 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0301279 |
| CD44 | CD44 molecule (Indian blood group) | -0.0298435 |
| EMP1 | epithelial membrane protein 1 | -0.0291428 |
| FLNA | filamin A, alpha | -0.0279227 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0269741 |
| NAV2 | neuron navigator 2 | -0.0266061 |
| APOD | apolipoprotein D | -0.0255438 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0247865 |
| PCBP2 | poly(rC) binding protein 2 | -0.0235601 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.022055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0218945 |
| RUNX1 | runt-related transcription factor 1 | -0.0214183 |
| HDAC9 | histone deacetylase 9 | -0.0213455 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0213312 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0211984 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0211922 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0207505 |
| HLA-E | major histocompatibility complex, class I, E | -0.0203739 |
| FRMD4A | FERM domain containing 4A | -0.0193742 |
| DIAPH1 | diaphanous-related formin 1 | -0.0189711 |
| EXOC6B | exocyst complex component 6B | -0.0187765 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179434 |
| SLC38A1 | solute carrier family 38, member 1 | -0.017889 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0178133 |
| IER3 | immediate early response 3 | -0.0172215 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0172119 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0168314 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0167417 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0152006 |
| RPL30 | ribosomal protein L30 | -0.015007 |
| RASAL2 | RAS protein activator like 2 | -0.0148616 |
| FBXO32 | F-box protein 32 | -0.0147073 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0146025 |
| STK10 | serine/threonine kinase 10 | -0.0144219 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0142623 |
| KLF6 | Kruppel-like factor 6 | -0.0139468 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0139229 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0138887 |
| RPS12 | ribosomal protein S12 | -0.0137006 |
| RHOB | ras homolog family member B | -0.0135523 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.013506 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0134349 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.013272 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0132363 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0131689 |
| TMEM117 | transmembrane protein 117 | -0.0129084 |
| ETV6 | ets variant 6 | -0.0128732 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0127504 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0127373 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0126669 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0124454 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0124351 |
| MT1X | metallothionein 1X | -0.0124183 |
| EZR | ezrin | -0.012242 |
| MCL1 | myeloid cell leukemia 1 | -0.0121025 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0120373 |
| MLPH | melanophilin | -0.0120272 |
| FILIP1 | filamin A interacting protein 1 | -0.0118649 |
| RPL31 | ribosomal protein L31 | -0.011817 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0117748 |
| JUN | jun proto-oncogene | -0.0117626 |
| TP63 | tumor protein p63 | -0.0116033 |
| NIBAN2 | niban apoptosis regulator 2 | -0.011461 |
| SVIL | supervillin | -0.011452 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0113229 |
| CERS2 | ceramide synthase 2 | -0.0109691 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0108842 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0108255 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0107271 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0105557 |
| SET | SET nuclear proto-oncogene | -0.0105356 |
| FUS | FUS RNA binding protein | -0.0104179 |
| CALR | calreticulin | -0.0103434 |
| CLIC4 | chloride intracellular channel 4 | -0.0103074 |
| RPL37A | ribosomal protein L37a | -0.0102946 |
| NAV1 | neuron navigator 1 | -0.0102269 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0102214 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -0.0101627 |
| SNX29 | sorting nexin 29 | -0.0101444 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.010112 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0100853 |
| PCBP3 | poly(rC) binding protein 3 | -0.0100229 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.00988535 |
