| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.154421 |
| VEGFA | vascular endothelial growth factor A | 0.0839937 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0835345 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0833717 |
| SPAG9 | sperm associated antigen 9 | 0.0773316 |
| PDE10A | phosphodiesterase 10A | 0.0730471 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.070388 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0701632 |
| NDRG1 | N-myc downstream regulated 1 | 0.068666 |
| ADM | adrenomedullin | 0.0686361 |
| MSN | moesin | 0.0668814 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0637188 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0627302 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0626489 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0615001 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.05875 |
| NAV2 | neuron navigator 2 | 0.0583173 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0569491 |
| PCBP2 | poly(rC) binding protein 2 | 0.055905 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0543643 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0530719 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0528095 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0527271 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0520941 |
| RPS2 | ribosomal protein S2 | 0.0508258 |
| FNIP1 | folliculin interacting protein 1 | 0.0499755 |
| GOLGA4 | golgin A4 | 0.0487647 |
| OPTN | optineurin | 0.046965 |
| SFTPA2 | surfactant protein A2 | 0.0468581 |
| OGA | O-GlcNAcase | 0.0434277 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0422881 |
| HELZ | helicase with zinc finger | 0.0413757 |
| ZNF292 | zinc finger protein 292 | 0.0401738 |
| FLNB | filamin B, beta | 0.0397525 |
| USP37 | ubiquitin specific peptidase 37 | 0.0392548 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0369198 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0366031 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0364898 |
| FN1 | fibronectin 1 | 0.0363563 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0358761 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0350153 |
| CDK19 | cyclin-dependent kinase 19 | 0.0344764 |
| ARRDC3 | arrestin domain containing 3 | 0.034426 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0344187 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0339758 |
| POTEF | POTE ankyrin domain family, member F | 0.0335292 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0331643 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0327219 |
| ATP13A3 | ATPase type 13A3 | 0.0323904 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0315635 |
| DSTN | destrin (actin depolymerizing factor) | 0.0314384 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0312194 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0312126 |
| BRD2 | bromodomain containing 2 | 0.0310299 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0302184 |
| RPS18 | ribosomal protein S18 | 0.030142 |
| NGLY1 | N-glycanase 1 | 0.0298229 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0297046 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296786 |
| CEP250 | centrosomal protein 250kDa | 0.0296671 |
| MATR3 | matrin 3 | 0.0295393 |
| ANLN | anillin, actin binding protein | 0.0288034 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0281311 |
| PGM3 | phosphoglucomutase 3 | 0.0277188 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0275042 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0274661 |
| RPL3 | ribosomal protein L3 | 0.0273574 |
| SNX3 | sorting nexin 3 | 0.0272459 |
| RND3 | Rho family GTPase 3 | 0.0272006 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0271694 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0264347 |
| NONO | non-POU domain containing, octamer-binding | 0.0261866 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0261669 |
| RYBP | RING1 and YY1 binding protein | 0.0260915 |
| CLTC | clathrin, heavy chain (Hc) | 0.0259694 |
| SEC24A | SEC24 family member A | 0.0259598 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0257702 |
| AHR | aryl hydrocarbon receptor | 0.0256832 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.025262 |
| TMF1 | TATA element modulatory factor 1 | 0.0252315 |
| FAM219A | family with sequence similarity 219, member A | 0.0252125 |
| MORF4L2 | mortality factor 4 like 2 | 0.0250933 |
| SRP54 | signal recognition particle 54kDa | 0.0250589 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0250061 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0248666 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0245624 |
| ARFGEF3 | ARFGEF family member 3 | 0.0240962 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.023597 |
| CADM1 | cell adhesion molecule 1 | 0.0233965 |
| PLS3 | plastin 3 | 0.0232915 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0232682 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0230877 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0230464 |
| USP12 | ubiquitin specific peptidase 12 | 0.0228921 |
| NOTCH2 | notch 2 | 0.0226633 |
| SETD5 | SET domain containing 5 | 0.0224037 |
| FLNA | filamin A, alpha | 0.0224013 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0223018 |
| CENPF | centromere protein F, 350/400kDa | 0.0221104 |
| DENND5A | DENN/MADD domain containing 5A | 0.0220955 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.316893 |
| GLIS3 | GLIS family zinc finger 3 | -0.146409 |
| FRMD4A | FERM domain containing 4A | -0.142193 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.111733 |
| IER3 | immediate early response 3 | -0.107048 |
| TMSB10 | thymosin beta 10 | -0.106148 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0969178 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0923248 |
| HLA-B | major histocompatibility complex, class I, B | -0.0914413 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0799124 |
| BICC1 | BicC family RNA binding protein 1 | -0.0795222 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0763476 |
| COL6A3 | collagen, type VI, alpha 3 | -0.072751 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.071138 |
| HMGA2 | high mobility group AT-hook 2 | -0.0696904 |
| AHNAK | AHNAK nucleoprotein | -0.0682365 |
| FTL | ferritin, light polypeptide | -0.0620442 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0604944 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0578724 |
| CD44 | CD44 molecule (Indian blood group) | -0.0568728 |
| VCAN | versican | -0.0561536 |
| RPL35A | ribosomal protein L35a | -0.0544309 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0543781 |
| MT2A | metallothionein 2A | -0.0535995 |
| RPS24 | ribosomal protein S24 | -0.05221 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0500494 |
| CDH13 | cadherin 13 | -0.0462148 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0423724 |
| RPLP2 | ribosomal protein, large, P2 | -0.0411882 |
| NAV1 | neuron navigator 1 | -0.0407056 |
| RPL23 | ribosomal protein L23 | -0.0378182 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0378111 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0376008 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0367558 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0364836 |
| GPC6 | glypican 6 | -0.0352154 |
| RPLP1 | ribosomal protein, large, P1 | -0.0345052 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0344971 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0344673 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0343067 |
| PTMA | prothymosin, alpha | -0.0342286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0341624 |
| THBS1 | thrombospondin 1 | -0.0331955 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0331947 |
| RRBP1 | ribosome binding protein 1 | -0.032929 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0326536 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0325487 |
| RASAL2 | RAS protein activator like 2 | -0.0315009 |
| RPL12 | ribosomal protein L12 | -0.0314721 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0311829 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0310994 |
| TUBB | tubulin, beta class I | -0.0310743 |
| NRP1 | neuropilin 1 | -0.030682 |
| RPS23 | ribosomal protein S23 | -0.0302525 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0302319 |
| RPS21 | ribosomal protein S21 | -0.029657 |
| ENO1 | enolase 1, (alpha) | -0.0295521 |
| EGR1 | early growth response 1 | -0.0295306 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0294894 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0291989 |
| COL1A1 | collagen, type I, alpha 1 | -0.0291843 |
| ANXA2 | annexin A2 | -0.0285616 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0284252 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.027981 |
| EFNA5 | ephrin-A5 | -0.0273354 |
| VCL | vinculin | -0.0271339 |
| RPS8 | ribosomal protein S8 | -0.0271247 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0254693 |
| INHBA | inhibin, beta A | -0.025443 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0253375 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0250894 |
| SVIL | supervillin | -0.0250066 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0245264 |
| RPL36 | ribosomal protein L36 | -0.0245157 |
| TPM4 | tropomyosin 4 | -0.0244188 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0243651 |
| FOXP1 | forkhead box P1 | -0.0241505 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0238078 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.023727 |
| GNAS | GNAS complex locus | -0.0236636 |
| CLMP | CXADR-like membrane protein | -0.0235746 |
| KRT19 | keratin 19, type I | -0.0234022 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0233929 |
| CDK6 | cyclin-dependent kinase 6 | -0.0233689 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0233161 |
| RNF213 | ring finger protein 213 | -0.023298 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0231045 |
| TENM2 | teneurin transmembrane protein 2 | -0.0230134 |
| KLHL5 | kelch-like family member 5 | -0.0229579 |
| TMSB4X | thymosin beta 4, X-linked | -0.0229184 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0227806 |
| RPL34 | ribosomal protein L34 | -0.0226418 |
| RPL26 | ribosomal protein L26 | -0.0225407 |
| FAM20C | family with sequence similarity 20, member C | -0.0225285 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0225141 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0224457 |
| RPS19 | ribosomal protein S19 | -0.0222342 |
| RPL36A | ribosomal protein L36a | -0.0221664 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0219286 |
| XAF1 | XIAP associated factor 1 | -0.0219284 |
