| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.127277 |
| GOLGA4 | golgin A4 | 0.0947426 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0748413 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0687393 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.067218 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.065914 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0657428 |
| YBX3 | Y box binding protein 3 | 0.0647344 |
| ZNF292 | zinc finger protein 292 | 0.0609421 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0558836 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0549948 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0548112 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0537721 |
| RBM25 | RNA binding motif protein 25 | 0.0530745 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0504545 |
| PKM | pyruvate kinase, muscle | 0.0504476 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0496646 |
| RBM39 | RNA binding motif protein 39 | 0.0496416 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0490172 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0488287 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0483842 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0473804 |
| NKTR | natural killer cell triggering receptor | 0.0464259 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0461218 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0452536 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0449859 |
| RPS2 | ribosomal protein S2 | 0.0448849 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0440849 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0420743 |
| DST | dystonin | 0.0415543 |
| SET | SET nuclear proto-oncogene | 0.0414416 |
| CCDC88A | coiled-coil domain containing 88A | 0.0411944 |
| FMNL2 | formin-like 2 | 0.0401125 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0397412 |
| SETD5 | SET domain containing 5 | 0.0395309 |
| MATR3 | matrin 3 | 0.039329 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0368259 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0365561 |
| CAPRIN2 | caprin family member 2 | 0.0364302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0360474 |
| CLTC | clathrin, heavy chain (Hc) | 0.0358505 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0357075 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.035594 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0355899 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.035564 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0354365 |
| SEPTIN2 | septin 2 | 0.035033 |
| FLNB | filamin B, beta | 0.0347333 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0340806 |
| DNER | delta/notch-like EGF repeat containing | 0.0340186 |
| ATM | ATM serine/threonine kinase | 0.0335338 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0333962 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0332364 |
| SPAG9 | sperm associated antigen 9 | 0.0328968 |
| ZNF207 | zinc finger protein 207 | 0.0320967 |
| CDCP1 | CUB domain containing protein 1 | 0.0318249 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0317436 |
| MSN | moesin | 0.0316576 |
| PTMA | prothymosin, alpha | 0.0313025 |
| ATP13A3 | ATPase type 13A3 | 0.0312795 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0302337 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0300513 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0300156 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0298474 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0296332 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0295618 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0294801 |
| CD44 | CD44 molecule (Indian blood group) | 0.0294472 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0294266 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0293381 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0288385 |
| PNN | pinin, desmosome associated protein | 0.0286803 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0282525 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0282518 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.028064 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0280153 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.027815 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0277711 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.027739 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0277023 |
| JMJD1C | jumonji domain containing 1C | 0.026891 |
| ITSN2 | intersectin 2 | 0.0268645 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0268615 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0267376 |
| SRP54 | signal recognition particle 54kDa | 0.0265177 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0262988 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0261226 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0260611 |
| ABI2 | abl-interactor 2 | 0.0260506 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0260419 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0258954 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0258454 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0257153 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0255402 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0253476 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0253326 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0252014 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0251037 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0250504 |
| SEC24A | SEC24 family member A | 0.0250474 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.119804 |
| RPLP1 | ribosomal protein, large, P1 | -0.0598564 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0577209 |
| HMGA2 | high mobility group AT-hook 2 | -0.0498337 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0493765 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0433805 |
| DEK | DEK proto-oncogene | -0.04161 |
| GNAS | GNAS complex locus | -0.0377691 |
| RPL35A | ribosomal protein L35a | -0.0361047 |
| RIGI | RNA sensor RIG-I | -0.0356635 |
| INTS6 | integrator complex subunit 6 | -0.0331928 |
| PRELID2 | PRELI domain containing 2 | -0.0326192 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0317716 |
| JAK1 | Janus kinase 1 | -0.0314224 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0303443 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0297549 |
| IER3 | immediate early response 3 | -0.0294098 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0291114 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0287683 |
| BMERB1 | bMERB domain containing 1 | -0.0284681 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0282461 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0281056 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0278129 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0275334 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0270325 |
| PANX1 | pannexin 1 | -0.027018 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0268037 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0263336 |
| GPHN | gephyrin | -0.026049 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0258095 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0256127 |
| HLA-A | major histocompatibility complex, class I, A | -0.0254974 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0247032 |
| ATG12 | autophagy related 12 | -0.0246745 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0244823 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0243126 |
| AOPEP | aminopeptidase O (putative) | -0.0240275 |
| E2F3 | E2F transcription factor 3 | -0.023811 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -0.02367 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0231304 |
| H3-3B | H3.3 histone B | -0.0229098 |
| CAVIN1 | caveolae associated protein 1 | -0.0228754 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0226788 |
| RPS8 | ribosomal protein S8 | -0.0226025 |
| RPS24 | ribosomal protein S24 | -0.0224024 |
| HLA-B | major histocompatibility complex, class I, B | -0.0222721 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0221591 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0219016 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0214414 |
| RYBP | RING1 and YY1 binding protein | -0.0212512 |
| IFI44 | interferon-induced protein 44 | -0.0211783 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0210785 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0209714 |
| SVIL | supervillin | -0.0209234 |
| FOXO3 | forkhead box O3 | -0.0208889 |
| RPS21 | ribosomal protein S21 | -0.0207317 |
| UBE3C | ubiquitin protein ligase E3C | -0.0206835 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0205434 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0204589 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0203661 |
| CTBP2 | C-terminal binding protein 2 | -0.0202116 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0201528 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0201411 |
| RPS11 | ribosomal protein S11 | -0.0201285 |
| ARF1 | ADP-ribosylation factor 1 | -0.0198614 |
| EGR1 | early growth response 1 | -0.0198159 |
| RPS19 | ribosomal protein S19 | -0.0197976 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0196759 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0196756 |
| SPAG16 | sperm associated antigen 16 | -0.0195723 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0194333 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.019413 |
| SGO2 | shugoshin 2 | -0.0193859 |
| RPL38 | ribosomal protein L38 | -0.0192046 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.0192013 |
| NOL7 | nucleolar protein 7, 27kDa | -0.0189782 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0189114 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0188293 |
| RPL8 | ribosomal protein L8 | -0.0186851 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.018683 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.018644 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0186241 |
| IFT20 | intraflagellar transport 20 | -0.0186088 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0185854 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0185795 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0185761 |
| RPS29 | ribosomal protein S29 | -0.0182718 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0182558 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0181803 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0181316 |
| FOXN3 | forkhead box N3 | -0.0180262 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0180225 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0180101 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0179929 |
| RPL36 | ribosomal protein L36 | -0.0179837 |
| EXPH5 | exophilin 5 | -0.0178795 |
| SETX | senataxin | -0.0178341 |
| FAM53C | family with sequence similarity 53, member C | -0.0178166 |
| XBP1 | X-box binding protein 1 | -0.0177477 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0177009 |
