| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.198177 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.10314 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0856874 |
| CANX | calnexin | 0.076145 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.06539 |
| ITGA1 | integrin, alpha 1 | 0.0579798 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0545605 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0488061 |
| MKI67 | marker of proliferation Ki-67 | 0.0438446 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0399406 |
| CD109 | CD109 molecule | 0.0388201 |
| OGA | O-GlcNAcase | 0.0385223 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0381092 |
| SMYD3 | SET and MYND domain containing 3 | 0.037897 |
| FAM13A | family with sequence similarity 13, member A | 0.0367662 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0365118 |
| ARRDC3 | arrestin domain containing 3 | 0.0363318 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0357348 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0351307 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0350879 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0341543 |
| NPC1 | Niemann-Pick disease, type C1 | 0.033375 |
| B2M | beta-2-microglobulin | 0.0331439 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0328248 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0327834 |
| TXNIP | thioredoxin interacting protein | 0.0325443 |
| CLTC | clathrin, heavy chain (Hc) | 0.032454 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0319844 |
| RO60 | Ro60, Y RNA binding protein | 0.0318863 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.031629 |
| CDCP1 | CUB domain containing protein 1 | 0.0310544 |
| CENPF | centromere protein F, 350/400kDa | 0.0307978 |
| PTK2 | protein tyrosine kinase 2 | 0.0305787 |
| YME1L1 | YME1-like 1 ATPase | 0.0305231 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0303763 |
| PRELID2 | PRELI domain containing 2 | 0.0298523 |
| XPO1 | exportin 1 | 0.0298157 |
| APP | amyloid beta (A4) precursor protein | 0.0297187 |
| SQSTM1 | sequestosome 1 | 0.0295994 |
| DSG2 | desmoglein 2 | 0.0293441 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0291359 |
| TMEM156 | transmembrane protein 156 | 0.0284677 |
| SMOX | spermine oxidase | 0.0283211 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0275014 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0271854 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0269822 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0268132 |
| NEK7 | NIMA-related kinase 7 | 0.0266411 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0264259 |
| BBX | bobby sox homolog (Drosophila) | 0.0263908 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0261032 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0259935 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.02579 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0257789 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0251118 |
| ANLN | anillin, actin binding protein | 0.0250784 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0250717 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0238887 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0237098 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0237005 |
| CALU | calumenin | 0.0234967 |
| SECISBP2L | SECIS binding protein 2-like | 0.023238 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0231618 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0230841 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0229997 |
| DENND4C | DENN/MADD domain containing 4C | 0.0226063 |
| AFDN | afadin, adherens junction formation factor | 0.0222738 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0221639 |
| RTN4 | reticulon 4 | 0.0221517 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0221048 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0219655 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0219183 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0218939 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0218027 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.021799 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0216838 |
| HELZ | helicase with zinc finger | 0.0213772 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0212926 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0212612 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0212561 |
| TPM3 | tropomyosin 3 | 0.0211049 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0209181 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0208354 |
| TMEM123 | transmembrane protein 123 | 0.0208236 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0205962 |
| TPR | translocated promoter region, nuclear basket protein | 0.0205875 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.020546 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0205139 |
| CEP95 | centrosomal protein 95kDa | 0.0204339 |
| SGO2 | shugoshin 2 | 0.0204016 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0203225 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0202652 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0202342 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0202071 |
| SNX13 | sorting nexin 13 | 0.0201343 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0200985 |
| RNF145 | ring finger protein 145 | 0.0199873 |
| FBXO32 | F-box protein 32 | 0.0197784 |
| AHR | aryl hydrocarbon receptor | 0.0195643 |
| INSIG2 | insulin induced gene 2 | 0.0193973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | -0.192685 |
| NRG1 | neuregulin 1 | -0.14976 |
| VCL | vinculin | -0.106974 |
| HMGA2 | high mobility group AT-hook 2 | -0.0978057 |
| NTN4 | netrin 4 | -0.0903243 |
| SYT1 | synaptotagmin I | -0.0877148 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0764978 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0704105 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.067451 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0670737 |
| NRP1 | neuropilin 1 | -0.0640829 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0595706 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0585281 |
| PALLD | palladin, cytoskeletal associated protein | -0.0546928 |
| KSR1 | kinase suppressor of ras 1 | -0.054164 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0521353 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0503062 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0496604 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0467847 |
| RAB10 | RAB10, member RAS oncogene family | -0.0451229 |
| EGR1 | early growth response 1 | -0.0426931 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0422524 |
| FN1 | fibronectin 1 | -0.0414952 |
| AEBP2 | AE binding protein 2 | -0.0414656 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0406529 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0402399 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0401705 |
| VMP1 | vacuole membrane protein 1 | -0.0397754 |
| ACTG1 | actin gamma 1 | -0.0388822 |
| FHL2 | four and a half LIM domains 2 | -0.0379467 |
| RASAL2 | RAS protein activator like 2 | -0.0369202 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0365865 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0360684 |
| NXN | nucleoredoxin | -0.035961 |
| ZNF644 | zinc finger protein 644 | -0.0358868 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0355441 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0353878 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0353118 |
| GLIS3 | GLIS family zinc finger 3 | -0.0352641 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0350804 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0349172 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0346757 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0331876 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0331421 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0328367 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0326665 |
| POTEF | POTE ankyrin domain family, member F | -0.0320481 |
| TOP1 | topoisomerase (DNA) I | -0.0318962 |
| INTS6 | integrator complex subunit 6 | -0.0317097 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0312372 |
| CTBP2 | C-terminal binding protein 2 | -0.0308268 |
| RAB31 | RAB31, member RAS oncogene family | -0.0306819 |
| VIM | vimentin | -0.0300186 |
| UBAP1 | ubiquitin associated protein 1 | -0.0296985 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0295237 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0285639 |
| GLCCI1 | glucocorticoid induced 1 | -0.0281956 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0274931 |
| COPA | coatomer protein complex, subunit alpha | -0.0274859 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0272999 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0272393 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0271454 |
| AOPEP | aminopeptidase O (putative) | -0.0269809 |
| CDK13 | cyclin-dependent kinase 13 | -0.0269777 |
| RAI14 | retinoic acid induced 14 | -0.0266533 |
| VCAN | versican | -0.0266218 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0265933 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0264858 |
| TJP1 | tight junction protein 1 | -0.0263659 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0260781 |
| FTL | ferritin, light polypeptide | -0.0259697 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0257827 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0255243 |
| SMAD3 | SMAD family member 3 | -0.0252943 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0250401 |
| MAP4 | microtubule-associated protein 4 | -0.0249055 |
| SIK3 | SIK family kinase 3 | -0.024791 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0247879 |
| LMNA | lamin A/C | -0.0247702 |
| ECE1 | endothelin converting enzyme 1 | -0.0246805 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.024638 |
| IL1R1 | interleukin 1 receptor, type I | -0.0245809 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0242907 |
| WDR59 | WD repeat domain 59 | -0.0239065 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.023773 |
| ANKRD28 | ankyrin repeat domain 28 | -0.023318 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.0232921 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0232202 |
| NAV1 | neuron navigator 1 | -0.023207 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.023202 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.0231795 |
| GPATCH2L | G patch domain containing 2-like | -0.0230864 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0229823 |
| BRD2 | bromodomain containing 2 | -0.0229711 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0229132 |
| SDC2 | syndecan 2 | -0.0229065 |
| TNNC1 | troponin C type 1 (slow) | -0.022778 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0227652 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0227591 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0225366 |
