| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.199501 |
| FTL | ferritin, light polypeptide | 0.153959 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.13128 |
| EZR | ezrin | 0.11175 |
| NDRG1 | N-myc downstream regulated 1 | 0.111477 |
| LDHA | lactate dehydrogenase A | 0.0882331 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0842793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0835985 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0833334 |
| KRT18 | keratin 18, type I | 0.0786676 |
| PGK1 | phosphoglycerate kinase 1 | 0.0754999 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0752412 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0722698 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0623957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.060651 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.059263 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0568743 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0556616 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0556527 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0548696 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0512491 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0511926 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0510437 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0508061 |
| PKM | pyruvate kinase, muscle | 0.0506376 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0504552 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0501115 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0491458 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0491189 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0477584 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0473437 |
| TMEM123 | transmembrane protein 123 | 0.0463182 |
| WDR43 | WD repeat domain 43 | 0.0461311 |
| KRT19 | keratin 19, type I | 0.0458466 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0449902 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0440138 |
| ANXA2 | annexin A2 | 0.0425799 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0416197 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0411865 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0404677 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0392128 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.038603 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.038584 |
| MYO10 | myosin X | 0.0383545 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0382611 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0372955 |
| TJP2 | tight junction protein 2 | 0.0362822 |
| AHNAK | AHNAK nucleoprotein | 0.036158 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0360905 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0356216 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0354162 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0351761 |
| FBXO11 | F-box protein 11 | 0.0350544 |
| TPM4 | tropomyosin 4 | 0.0348743 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0347747 |
| VGLL4 | vestigial-like family member 4 | 0.0346914 |
| NFIA | nuclear factor I/A | 0.034419 |
| ADM | adrenomedullin | 0.0340693 |
| CANX | calnexin | 0.0334271 |
| EHF | ets homologous factor | 0.0332387 |
| MYOF | myoferlin | 0.0327809 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0327233 |
| YBX1 | Y box binding protein 1 | 0.0326065 |
| TOP1 | topoisomerase (DNA) I | 0.0321097 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0318862 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0318221 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0317054 |
| RIOK3 | RIO kinase 3 | 0.0317047 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0316894 |
| VEGFA | vascular endothelial growth factor A | 0.0313795 |
| RAD51B | RAD51 paralog B | 0.0309703 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0307942 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0304996 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.030431 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0301585 |
| HM13 | histocompatibility (minor) 13 | 0.0299745 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298563 |
| ANXA1 | annexin A1 | 0.029636 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0296011 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0295335 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0293277 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0291455 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0290396 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0288996 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0288766 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0288697 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0285771 |
| MYO1B | myosin IB | 0.0285116 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0283552 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0283114 |
| HDLBP | high density lipoprotein binding protein | 0.0282716 |
| JUP | junction plakoglobin | 0.0280015 |
| TXNIP | thioredoxin interacting protein | 0.027758 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0277458 |
| FNBP1L | formin binding protein 1-like | 0.027641 |
| SETD5 | SET domain containing 5 | 0.0275045 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0272475 |
| KRT8 | keratin 8, type II | 0.0272004 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0271239 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0268345 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.118004 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0741996 |
| RPS12 | ribosomal protein S12 | -0.0514292 |
| EXOC6B | exocyst complex component 6B | -0.0503099 |
| RPLP2 | ribosomal protein, large, P2 | -0.049116 |
| RPS6 | ribosomal protein S6 | -0.0475645 |
| RPLP1 | ribosomal protein, large, P1 | -0.0459487 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0429059 |
| NKTR | natural killer cell triggering receptor | -0.0409941 |
| YAP1 | Yes-associated protein 1 | -0.0408553 |
| GOLGB1 | golgin B1 | -0.0398447 |
| TXNRD1 | thioredoxin reductase 1 | -0.0397811 |
| RTN4 | reticulon 4 | -0.0390232 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0379614 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0379003 |
| RPS29 | ribosomal protein S29 | -0.0374433 |
| GPHN | gephyrin | -0.0374341 |
| MKI67 | marker of proliferation Ki-67 | -0.036953 |
| RPS21 | ribosomal protein S21 | -0.036181 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0340699 |
| RPL35A | ribosomal protein L35a | -0.0340336 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0335262 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0329945 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0327608 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0325414 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0312322 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0311399 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0310701 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | -0.030308 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0302064 |
| RPL32 | ribosomal protein L32 | -0.0295984 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0286726 |
| RPL31 | ribosomal protein L31 | -0.0285918 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0280696 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0279332 |
| RYBP | RING1 and YY1 binding protein | -0.0274644 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0264353 |
| FAF2 | Fas associated factor family member 2 | -0.0263756 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0263694 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0263293 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0259138 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0255361 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0254202 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.025297 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.025057 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0249817 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0249595 |
| RPL37A | ribosomal protein L37a | -0.0249261 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0248008 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0247838 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0243543 |
| RPL34 | ribosomal protein L34 | -0.0243071 |
| ACTG1 | actin gamma 1 | -0.0242578 |
| CST3 | cystatin C | -0.0241002 |
| MEF2A | myocyte enhancer factor 2A | -0.0240896 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.023763 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0232323 |
| STRBP | spermatid perinuclear RNA binding protein | -0.0231768 |
| IL18 | interleukin 18 | -0.0231381 |
| RBM25 | RNA binding motif protein 25 | -0.0231275 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0230285 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0228442 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0225828 |
| RPL12 | ribosomal protein L12 | -0.0225505 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0223305 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0223166 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0222941 |
| CENPE | centromere protein E, 312kDa | -0.0222923 |
| RPL18 | ribosomal protein L18 | -0.0221644 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0220844 |
| RPL21 | ribosomal protein L21 | -0.0220559 |
| RPL30 | ribosomal protein L30 | -0.022036 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0219913 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0218587 |
| CD46 | CD46 molecule, complement regulatory protein | -0.021799 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0217786 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0217559 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | -0.0217086 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0216283 |
| RPL38 | ribosomal protein L38 | -0.021594 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0215198 |
| RPS13 | ribosomal protein S13 | -0.0214479 |
| CCNL1 | cyclin L1 | -0.0212658 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0212571 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0212329 |
| PKP4 | plakophilin 4 | -0.0212063 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0211515 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0210829 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.020969 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0208932 |
| KIF21A | kinesin family member 21A | -0.0207841 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0207355 |
| TLK1 | tousled-like kinase 1 | -0.0204254 |
| OXR1 | oxidation resistance 1 | -0.0202955 |
| RPL37 | ribosomal protein L37 | -0.0199935 |
| PERP | PERP, TP53 apoptosis effector | -0.0199323 |
| RPS27 | ribosomal protein S27 | -0.0197484 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0196797 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0196029 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0193861 |
