| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.136775 |
| AREG | amphiregulin | 0.135215 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.124382 |
| NDRG1 | N-myc downstream regulated 1 | 0.122646 |
| EZR | ezrin | 0.10433 |
| RPS6 | ribosomal protein S6 | 0.0941808 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0908686 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0871067 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0833635 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0822391 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0772467 |
| RPS2 | ribosomal protein S2 | 0.0754809 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0731732 |
| ANXA1 | annexin A1 | 0.0722908 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0717016 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0680397 |
| GOLGA4 | golgin A4 | 0.0676002 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0643747 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0631475 |
| EREG | epiregulin | 0.0625753 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0621686 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0590354 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.055863 |
| LDHA | lactate dehydrogenase A | 0.0554641 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0519111 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.051152 |
| PARD3 | par-3 family cell polarity regulator | 0.0486407 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0449514 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0446526 |
| RPL3 | ribosomal protein L3 | 0.0438298 |
| TOP1 | topoisomerase (DNA) I | 0.0408308 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.038868 |
| CPOX | coproporphyrinogen oxidase | 0.038481 |
| BRD2 | bromodomain containing 2 | 0.0376298 |
| RNF145 | ring finger protein 145 | 0.0373829 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0366679 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0366054 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0364692 |
| SBF2 | SET binding factor 2 | 0.0361452 |
| DSPP | dentin sialophosphoprotein | 0.0360118 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.035949 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0357902 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0356111 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0355656 |
| RPS3 | ribosomal protein S3 | 0.0352106 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0350853 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.0349823 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.034744 |
| PCBP2 | poly(rC) binding protein 2 | 0.033505 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0334437 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.033279 |
| SNX9 | sorting nexin 9 | 0.0331895 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0326393 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0325202 |
| PNN | pinin, desmosome associated protein | 0.0324363 |
| ANLN | anillin, actin binding protein | 0.0317709 |
| RPS12 | ribosomal protein S12 | 0.0315618 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.031402 |
| ENO1 | enolase 1, (alpha) | 0.0311888 |
| LAMC2 | laminin, gamma 2 | 0.0311626 |
| PKM | pyruvate kinase, muscle | 0.0311383 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0309426 |
| ZNF292 | zinc finger protein 292 | 0.0307933 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0304999 |
| RPL21 | ribosomal protein L21 | 0.0302697 |
| SLMAP | sarcolemma associated protein | 0.0298285 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.029752 |
| PLAUR | plasminogen activator, urokinase receptor | 0.029678 |
| BBX | bobby sox homolog (Drosophila) | 0.0294667 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0293237 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0291447 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0290933 |
| RACK1 | receptor for activated C kinase 1 | 0.0289861 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0285765 |
| TXNIP | thioredoxin interacting protein | 0.0281847 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0281369 |
| WDR43 | WD repeat domain 43 | 0.027938 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.027774 |
| VEGFA | vascular endothelial growth factor A | 0.0276442 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0276386 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0271128 |
| RPL7A | ribosomal protein L7a | 0.0268505 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0268253 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0268227 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0267489 |
| RPS18 | ribosomal protein S18 | 0.0266092 |
| SET | SET nuclear proto-oncogene | 0.0265639 |
| MYO1B | myosin IB | 0.0262327 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0259739 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0259079 |
| FOSL1 | FOS-like antigen 1 | 0.0258379 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0258272 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0256939 |
| SPAG9 | sperm associated antigen 9 | 0.0256028 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0255269 |
| CENPF | centromere protein F, 350/400kDa | 0.0255085 |
| NUP58 | nucleoporin 58 | 0.0252472 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0249784 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0249381 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0248085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0844021 |
| VCL | vinculin | -0.0826271 |
| EGFR | epidermal growth factor receptor | -0.0742265 |
| HMGA2 | high mobility group AT-hook 2 | -0.0684588 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0658048 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0655415 |
| MTAP | methylthioadenosine phosphorylase | -0.0624214 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0616322 |
| PHF14 | PHD finger protein 14 | -0.046944 |
| ATXN1 | ataxin 1 | -0.0467145 |
| RPS24 | ribosomal protein S24 | -0.0461637 |
| LAMA4 | laminin, alpha 4 | -0.0458475 |
| EHBP1 | EH domain binding protein 1 | -0.045623 |
| SEPTIN9 | septin 9 | -0.0414701 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0413436 |
| SERINC5 | serine incorporator 5 | -0.0407115 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.038893 |
| CDK13 | cyclin-dependent kinase 13 | -0.0376287 |
| RAB10 | RAB10, member RAS oncogene family | -0.0361402 |
| AHNAK | AHNAK nucleoprotein | -0.0350646 |
| FHL2 | four and a half LIM domains 2 | -0.0349679 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0345608 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0340909 |
| CUX1 | cut-like homeobox 1 | -0.033723 |
| SMYD3 | SET and MYND domain containing 3 | -0.0336445 |
| ABR | active BCR-related | -0.0333855 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0301023 |
| TENM3 | teneurin transmembrane protein 3 | -0.0298428 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0294429 |
| SMAD3 | SMAD family member 3 | -0.0291691 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0287051 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0284504 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0283624 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0276402 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0272476 |
| CCND1 | cyclin D1 | -0.027089 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0265075 |
| SGMS2 | sphingomyelin synthase 2 | -0.0264136 |
| YAP1 | Yes-associated protein 1 | -0.026325 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0262242 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0262109 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0262039 |
| EXOC4 | exocyst complex component 4 | -0.0260869 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0257422 |
| RAD51B | RAD51 paralog B | -0.0247124 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0244475 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0244135 |
| AOPEP | aminopeptidase O (putative) | -0.024333 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0241864 |
| CMIP | c-Maf inducing protein | -0.0240911 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -0.0240544 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0239968 |
| KITLG | KIT ligand | -0.0239048 |
| RPL35A | ribosomal protein L35a | -0.0236548 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0234789 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0234147 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0232543 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.0229966 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0228714 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0227853 |
| SPON1 | spondin 1, extracellular matrix protein | -0.022325 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0222574 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0222272 |
| EXOC6B | exocyst complex component 6B | -0.0222151 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0220253 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0218379 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0217957 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0216967 |
| TNS3 | tensin 3 | -0.0214449 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0214285 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0213667 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0211187 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0210954 |
| ATXN7L1 | ataxin 7-like 1 | -0.0207843 |
| KLF6 | Kruppel-like factor 6 | -0.0207302 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0202842 |
| ARF1 | ADP-ribosylation factor 1 | -0.0202075 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0196108 |
| SPIDR | scaffolding protein involved in DNA repair | -0.019594 |
| RPLP1 | ribosomal protein, large, P1 | -0.0195752 |
| ANXA3 | annexin A3 | -0.0195641 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | -0.0195613 |
| YLPM1 | YLP motif containing 1 | -0.0192651 |
| PCNX4 | pecanex 4 | -0.0191713 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0191139 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0190648 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0188943 |
| MYOF | myoferlin | -0.0188557 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0188516 |
| ATG7 | autophagy related 7 | -0.0188153 |
| RPS4X | ribosomal protein S4, X-linked | -0.0185558 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0185237 |
| COMMD10 | COMM domain containing 10 | -0.0184753 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.0184281 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0183972 |
| EMP1 | epithelial membrane protein 1 | -0.0183088 |
| ZNF518A | zinc finger protein 518A | -0.0182304 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.0180297 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0179798 |
| AK1 | adenylate kinase 1 | -0.0178668 |
