| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.183027 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.08259 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0800233 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0676863 |
| ITGA6 | integrin, alpha 6 | 0.0636329 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0613425 |
| POTEF | POTE ankyrin domain family, member F | 0.0597649 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0579876 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0575805 |
| PCBP2 | poly(rC) binding protein 2 | 0.0565134 |
| PKM | pyruvate kinase, muscle | 0.0542509 |
| VMP1 | vacuole membrane protein 1 | 0.0542402 |
| EZR | ezrin | 0.0537792 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0501077 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0463338 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0463024 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0457617 |
| MSN | moesin | 0.0425696 |
| DSPP | dentin sialophosphoprotein | 0.0423768 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0421116 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0416307 |
| LDHA | lactate dehydrogenase A | 0.0415925 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0415537 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0414502 |
| ANXA2 | annexin A2 | 0.0413002 |
| VCL | vinculin | 0.0404753 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0403611 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0401366 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0400169 |
| BCL2L1 | BCL2-like 1 | 0.0397127 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0396546 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0396326 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0384265 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0375208 |
| NDRG1 | N-myc downstream regulated 1 | 0.0357251 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0354257 |
| TNS4 | tensin 4 | 0.0345974 |
| EGR1 | early growth response 1 | 0.0344867 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0341081 |
| KIZ | kizuna centrosomal protein | 0.0336278 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0336002 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0335313 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332269 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0331182 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0330773 |
| ASPH | aspartate beta-hydroxylase | 0.0318342 |
| CCNL1 | cyclin L1 | 0.0317362 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0317202 |
| RCOR1 | REST corepressor 1 | 0.0316911 |
| USP34 | ubiquitin specific peptidase 34 | 0.0316187 |
| CENPF | centromere protein F, 350/400kDa | 0.0314384 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0307353 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0306859 |
| SNX9 | sorting nexin 9 | 0.0306593 |
| ACTN1 | actinin, alpha 1 | 0.0305951 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0301495 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0299401 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0296877 |
| SEPTIN9 | septin 9 | 0.0293804 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0285706 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0285016 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0281357 |
| ANO6 | anoctamin 6 | 0.0280354 |
| TPM4 | tropomyosin 4 | 0.0280118 |
| FLNB | filamin B, beta | 0.027597 |
| ZNF638 | zinc finger protein 638 | 0.0269976 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0269774 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0266198 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0263526 |
| PCM1 | pericentriolar material 1 | 0.0262865 |
| MED13 | mediator complex subunit 13 | 0.0262499 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0262487 |
| LAMA4 | laminin, alpha 4 | 0.0260403 |
| FOSL1 | FOS-like antigen 1 | 0.0258672 |
| RPL3 | ribosomal protein L3 | 0.0256532 |
| TGM2 | transglutaminase 2 | 0.0255896 |
| FNIP1 | folliculin interacting protein 1 | 0.0254625 |
| ERBIN | erbb2 interacting protein | 0.0253871 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0251567 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0249005 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0247048 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0246167 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0245267 |
| TPM3 | tropomyosin 3 | 0.0242128 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0241601 |
| TXNIP | thioredoxin interacting protein | 0.0240297 |
| NAV2 | neuron navigator 2 | 0.0235654 |
| SET | SET nuclear proto-oncogene | 0.0234746 |
| DOCK9 | dedicator of cytokinesis 9 | 0.023351 |
| ANLN | anillin, actin binding protein | 0.0232545 |
| PFN1 | profilin 1 | 0.022887 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0227012 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0226884 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0224831 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0223942 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0222775 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0221484 |
| HMGA1 | high mobility group AT-hook 1 | 0.0217105 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0211078 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0208747 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.181745 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.116127 |
| PTMA | prothymosin, alpha | -0.0780191 |
| RPL35A | ribosomal protein L35a | -0.0766594 |
| RPS24 | ribosomal protein S24 | -0.0688358 |
| RPLP1 | ribosomal protein, large, P1 | -0.0653307 |
| RPL26 | ribosomal protein L26 | -0.0576146 |
| RPS8 | ribosomal protein S8 | -0.0539918 |
| RPL23 | ribosomal protein L23 | -0.0448347 |
| HMGB1 | high mobility group box 1 | -0.0423076 |
| KRT8 | keratin 8, type II | -0.0422295 |
| AHNAK | AHNAK nucleoprotein | -0.0415708 |
| SYT1 | synaptotagmin I | -0.0410569 |
| RPLP2 | ribosomal protein, large, P2 | -0.0403698 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0368845 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0350541 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0346049 |
| RPS27A | ribosomal protein S27a | -0.0337987 |
| RPL38 | ribosomal protein L38 | -0.0334716 |
| RPS6 | ribosomal protein S6 | -0.0332158 |
| RPS4X | ribosomal protein S4, X-linked | -0.0328811 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0328034 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0327198 |
| RUNX1 | runt-related transcription factor 1 | -0.0325859 |
| RPS21 | ribosomal protein S21 | -0.032349 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0314019 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0307819 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0296799 |
| RPL36A | ribosomal protein L36a | -0.0295968 |
| AOPEP | aminopeptidase O (putative) | -0.0281993 |
| RPL34 | ribosomal protein L34 | -0.0278136 |
| RPL13A | ribosomal protein L13a | -0.027628 |
| TMSB4X | thymosin beta 4, X-linked | -0.0267985 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0266863 |
| RPL19 | ribosomal protein L19 | -0.0266783 |
| RPL11 | ribosomal protein L11 | -0.0261809 |
| RPL4 | ribosomal protein L4 | -0.0260904 |
| RPL9 | ribosomal protein L9 | -0.0255865 |
| RPLP0 | ribosomal protein, large, P0 | -0.0253184 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0249806 |
| GNAS | GNAS complex locus | -0.0248719 |
| RPL31 | ribosomal protein L31 | -0.0243206 |
| RPL37A | ribosomal protein L37a | -0.0242785 |
| RPS3 | ribosomal protein S3 | -0.0238416 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0236635 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0229751 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0227595 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0225941 |
| SYK | spleen tyrosine kinase | -0.0225941 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0224942 |
| UBB | ubiquitin B | -0.0219733 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.021735 |
| HMGB2 | high mobility group box 2 | -0.0215953 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0210025 |
| RPS12 | ribosomal protein S12 | -0.020788 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0204894 |
| RPL37 | ribosomal protein L37 | -0.0202826 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0200653 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0197363 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0197142 |
| RPL14 | ribosomal protein L14 | -0.0196421 |
| CANX | calnexin | -0.0195637 |
| CAVIN1 | caveolae associated protein 1 | -0.0195145 |
| RPS20 | ribosomal protein S20 | -0.0193829 |
| TMSB10 | thymosin beta 10 | -0.0193435 |
| ACTG1 | actin gamma 1 | -0.0191304 |
| RPL36 | ribosomal protein L36 | -0.0188889 |
| WWOX | WW domain containing oxidoreductase | -0.0188748 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.018406 |
| TUBB | tubulin, beta class I | -0.0182329 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0180824 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0180368 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0179514 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0178761 |
| RPL30 | ribosomal protein L30 | -0.0178424 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0178416 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0177928 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0177682 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -0.0177303 |
| RPS29 | ribosomal protein S29 | -0.0175736 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0175552 |
| SMYD3 | SET and MYND domain containing 3 | -0.0175425 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0175071 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0174962 |
| NPR2 | natriuretic peptide receptor 2 | -0.0173796 |
| RPL32 | ribosomal protein L32 | -0.0173044 |
| XPO7 | exportin 7 | -0.0172945 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0172328 |
| RPL6 | ribosomal protein L6 | -0.0172114 |
| FOXP1 | forkhead box P1 | -0.0169722 |
| RPL5 | ribosomal protein L5 | -0.016629 |
| OGA | O-GlcNAcase | -0.0166251 |
| IER3 | immediate early response 3 | -0.0165677 |
| CDH13 | cadherin 13 | -0.0165415 |
| S100A10 | S100 calcium binding protein A10 | -0.0165248 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0164818 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0164279 |
| RPS19 | ribosomal protein S19 | -0.0163931 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0163672 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0163586 |
