Fish-Eye Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Fish eye disease (FED) is a form of genetic LCAT (lecithin-cholesterol acyltransferase) deficiency (see this term) characterized clinically by corneal opacifications, and biochemically by significantly reduced HDL cholesterol and partial LCAT enzyme deficiency. (Orphanet Rare Disease Ontology, Orphanet_79292)
External Link https://www.disgenet.org/browser/0/1/0/C0342895
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Genes

18 genes associated with the disease Fish-Eye Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOB apolipoprotein B
BRCA1 breast cancer 1, early onset
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CLU clusterin
COL8A2 collagen, type VIII, alpha 2
CSN3 casein kappa
GPR162 G protein-coupled receptor 162
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
IRS1 insulin receptor substrate 1
LCAT lecithin-cholesterol acyltransferase
PITX2 paired-like homeodomain 2
PTPRG protein tyrosine phosphatase, receptor type, G
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
ZEB1 zinc finger E-box binding homeobox 1