Fleck Corneal Dystrophy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Fleck corneal dystrophy (FCD) is a rare generally asymptomatic form of stromal corneal dystrophy (see this term) characterized by multiple asymptomatic, non-progressive opacities disseminated throughout the corneal stroma with no effect on visual acuity. (Orphanet Rare Disease Ontology, Orphanet_98970)
External Link https://www.disgenet.org/browser/0/1/0/C1562113
Similar Terms
Downloads & Tools

Genes

95 genes associated with the disease Fleck Corneal Dystrophy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGBL1 ATP/GTP binding protein-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANXA1 annexin A1
BIRC2 baculoviral IAP repeat containing 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD34 CD34 molecule
CDCA5 cell division cycle associated 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CLU clusterin
COL8A2 collagen, type VIII, alpha 2
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CRYAB crystallin, alpha B
DEPDC5 DEP domain containing 5
DNAAF3 dynein, axonemal, assembly factor 3
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGFR2 fibroblast growth factor receptor 2
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FOLR2 folate receptor 2 (fetal)
GCDH glutaryl-CoA dehydrogenase
GCHFR GTP cyclohydrolase I feedback regulator
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GRM5 glutamate receptor, metabotropic 5
HMGB1 high mobility group box 1
IL10 interleukin 10
IL12A interleukin 12A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JAK1 Janus kinase 1
JAK3 Janus kinase 3
KLF4 Kruppel-like factor 4 (gut)
LGI1 leucine-rich, glioma inactivated 1
LOC105375355 uroplakin-3b
LOXHD1 lipoxygenase homology domains 1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MDM4 MDM4, p53 regulator
MNAT1 MNAT CDK-activating kinase assembly factor 1
MSH3 mutS homolog 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR1H2 nuclear receptor subfamily 1, group H, member 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PANX1 pannexin 1
PANX2 pannexin 2
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIKFYVE phosphoinositide kinase, FYVE finger containing
PNKP polynucleotide kinase 3'-phosphatase
POU5F1 POU class 5 homeobox 1
PTK2B protein tyrosine kinase 2 beta
PTPRG protein tyrosine phosphatase, receptor type, G
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RELN reelin
RGS6 regulator of G-protein signaling 6
RPS6 ribosomal protein S6
SCN1A sodium channel, voltage gated, type I alpha subunit
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX2 SRY (sex determining region Y)-box 2
STATH statherin
TCF4 transcription factor 4
TESC tescalcin
TGFBI transforming growth factor, beta-induced, 68kDa
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
VEGFA vascular endothelial growth factor A
ZEB1 zinc finger E-box binding homeobox 1