| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.236417 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.194834 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.181707 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.170815 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.157468 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.144309 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.141316 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0941619 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0789661 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0744193 |
| ATP13A3 | ATPase type 13A3 | 0.0736398 |
| APP | amyloid beta (A4) precursor protein | 0.0703173 |
| FLNB | filamin B, beta | 0.0702232 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0701436 |
| FLNA | filamin A, alpha | 0.0681029 |
| NAV2 | neuron navigator 2 | 0.066017 |
| DST | dystonin | 0.0641134 |
| PLEC | plectin | 0.0614311 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0587775 |
| PGK1 | phosphoglycerate kinase 1 | 0.0550687 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0543428 |
| LOXL2 | lysyl oxidase-like 2 | 0.0539908 |
| PKM | pyruvate kinase, muscle | 0.0527158 |
| NDRG1 | N-myc downstream regulated 1 | 0.0523161 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0512065 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0505316 |
| TPM3 | tropomyosin 3 | 0.0485128 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0482815 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0476419 |
| COL5A1 | collagen, type V, alpha 1 | 0.0472543 |
| VIM | vimentin | 0.047047 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0465685 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0461542 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0448691 |
| CALR | calreticulin | 0.0447787 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0438804 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0438732 |
| TPM4 | tropomyosin 4 | 0.0435046 |
| MSN | moesin | 0.0434825 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0428022 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0427061 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0412369 |
| COL5A2 | collagen, type V, alpha 2 | 0.0411211 |
| RUNX1 | runt-related transcription factor 1 | 0.0406145 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0405761 |
| LDHA | lactate dehydrogenase A | 0.0397412 |
| SEPTIN9 | septin 9 | 0.0389839 |
| CD109 | CD109 molecule | 0.0384932 |
| FBN1 | fibrillin 1 | 0.0378493 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0372463 |
| LMNA | lamin A/C | 0.0371377 |
| C1D | C1D nuclear receptor corepressor | 0.0363789 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.035534 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.034968 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0336133 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0333804 |
| CD44 | CD44 molecule (Indian blood group) | 0.0333674 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0331064 |
| LAMB1 | laminin, beta 1 | 0.0329084 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0328338 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0327677 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.032634 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0323698 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0322535 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0322464 |
| RPL3 | ribosomal protein L3 | 0.0316486 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0315579 |
| AUTS2 | autism susceptibility candidate 2 | 0.0315227 |
| YEATS2 | YEATS domain containing 2 | 0.0314443 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0314401 |
| DTNA | dystrobrevin, alpha | 0.0311502 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0311316 |
| FMNL2 | formin-like 2 | 0.0310241 |
| TMSB4X | thymosin beta 4, X-linked | 0.0309838 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0307614 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0307344 |
| L1CAM | L1 cell adhesion molecule | 0.0304398 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0303397 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0303015 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0302685 |
| RAI1 | retinoic acid induced 1 | 0.0301328 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0292824 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0291408 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0291069 |
| NBAS | neuroblastoma amplified sequence | 0.0289126 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0287449 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0280209 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0279415 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277985 |
| PRELID2 | PRELI domain containing 2 | 0.0276328 |
| SBF2 | SET binding factor 2 | 0.0275339 |
| ZNF292 | zinc finger protein 292 | 0.027349 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0272471 |
| SET | SET nuclear proto-oncogene | 0.0271572 |
| HELZ | helicase with zinc finger | 0.0271274 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0270419 |
| AFDN | afadin, adherens junction formation factor | 0.0269603 |
| DENND5A | DENN/MADD domain containing 5A | 0.0268461 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0268273 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0265769 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.314402 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0821363 |
| TMSB10 | thymosin beta 10 | -0.0749245 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0689665 |
| S100A10 | S100 calcium binding protein A10 | -0.0595508 |
| CSTB | cystatin B (stefin B) | -0.0486198 |
| AHNAK | AHNAK nucleoprotein | -0.0463036 |
| MT2A | metallothionein 2A | -0.0460489 |
| MEIS2 | Meis homeobox 2 | -0.0453741 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0449086 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0438777 |
| UBC | ubiquitin C | -0.0435872 |
| MAP1B | microtubule-associated protein 1B | -0.0430193 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0428404 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0409604 |
| MX2 | MX dynamin-like GTPase 2 | -0.0386306 |
| HLA-C | major histocompatibility complex, class I, C | -0.0366582 |
| HLA-B | major histocompatibility complex, class I, B | -0.0365903 |
| GLIS3 | GLIS family zinc finger 3 | -0.0343884 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0335574 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0327971 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0311552 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0299772 |
| MT1X | metallothionein 1X | -0.0296447 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0288913 |
| H3-3B | H3.3 histone B | -0.0280874 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0280296 |
| FTL | ferritin, light polypeptide | -0.0280089 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0278028 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0273404 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0270007 |
| VCL | vinculin | -0.0265065 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0260536 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0257628 |
| NAV1 | neuron navigator 1 | -0.0256809 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0255449 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0252409 |
| CD99 | CD99 molecule | -0.0249206 |
| RIGI | RNA sensor RIG-I | -0.0247993 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0243323 |
| FBXO11 | F-box protein 11 | -0.0239626 |
| S100A6 | S100 calcium binding protein A6 | -0.0238485 |
| IER3 | immediate early response 3 | -0.0236784 |
| VMP1 | vacuole membrane protein 1 | -0.0236526 |
| RPL28 | ribosomal protein L28 | -0.0236238 |
| GOLGB1 | golgin B1 | -0.0234786 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233111 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0231255 |
| RPS24 | ribosomal protein S24 | -0.0229401 |
| TXNIP | thioredoxin interacting protein | -0.0227716 |
| RPLP1 | ribosomal protein, large, P1 | -0.0225994 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0224627 |
| FNDC3A | fibronectin type III domain containing 3A | -0.022384 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0220229 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0220012 |
| CANX | calnexin | -0.0219987 |
| TMEM263 | transmembrane protein 263 | -0.0219414 |
| SP100 | SP100 nuclear antigen | -0.0218307 |
| NPR2 | natriuretic peptide receptor 2 | -0.0217849 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0214709 |
| RPS15 | ribosomal protein S15 | -0.0214016 |
| SUCNR1 | succinate receptor 1 | -0.0211051 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0208601 |
| RPL35A | ribosomal protein L35a | -0.0207798 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0205823 |
| CAVIN1 | caveolae associated protein 1 | -0.0205132 |
| TUBB | tubulin, beta class I | -0.0204169 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0200308 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0199969 |
| GNAS | GNAS complex locus | -0.0199821 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0198242 |
| HMGB1 | high mobility group box 1 | -0.0197454 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0197165 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0195487 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0195373 |
| S100A9 | S100 calcium binding protein A9 | -0.0194922 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0193243 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0190594 |
| CDK12 | cyclin-dependent kinase 12 | -0.0188972 |
| ANXA2 | annexin A2 | -0.0188217 |
| RRBP1 | ribosome binding protein 1 | -0.0187502 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0187161 |
| LOX | lysyl oxidase | -0.0186815 |
| RASAL2 | RAS protein activator like 2 | -0.0186375 |
| CDK6 | cyclin-dependent kinase 6 | -0.0185828 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0182431 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0182183 |
| PTMA | prothymosin, alpha | -0.0178767 |
| EGR1 | early growth response 1 | -0.0177737 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0176673 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0176304 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0176195 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | -0.0174088 |
| TBCA | tubulin folding cofactor A | -0.0171553 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0171529 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.017144 |
| RPLP0 | ribosomal protein, large, P0 | -0.0170776 |
| RPS6 | ribosomal protein S6 | -0.0170378 |
| RPS21 | ribosomal protein S21 | -0.0169198 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0168698 |
