| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.267467 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.156623 |
| VIM | vimentin | 0.127285 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.111639 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.108555 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.103972 |
| GPC6 | glypican 6 | 0.0932348 |
| CD44 | CD44 molecule (Indian blood group) | 0.0862782 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0824271 |
| VCL | vinculin | 0.0814988 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0785059 |
| NAV2 | neuron navigator 2 | 0.0778316 |
| NRP2 | neuropilin 2 | 0.0763273 |
| FLNA | filamin A, alpha | 0.0642454 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0582572 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0578858 |
| PLEC | plectin | 0.0574363 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.057422 |
| PAX8 | paired box 8 | 0.0562251 |
| FMNL2 | formin-like 2 | 0.0553802 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0548825 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0544057 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0529558 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0528119 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0510007 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0499063 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0498754 |
| CALR | calreticulin | 0.048765 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0487519 |
| RPL4 | ribosomal protein L4 | 0.0482318 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0482111 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0447965 |
| APP | amyloid beta (A4) precursor protein | 0.0445424 |
| SDC4 | syndecan 4 | 0.0443845 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0436838 |
| PLK2 | polo-like kinase 2 | 0.0436086 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0419497 |
| DENND2B | DENN domain containing 2B | 0.041364 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0410281 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0406136 |
| ANXA2 | annexin A2 | 0.0404208 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0403277 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0402238 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0401287 |
| ITGAV | integrin, alpha V | 0.0399442 |
| PGK1 | phosphoglycerate kinase 1 | 0.0397731 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.039041 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0389513 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0386792 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0379112 |
| ATP13A3 | ATPase type 13A3 | 0.037643 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0372753 |
| CADM1 | cell adhesion molecule 1 | 0.0370346 |
| FAT1 | FAT atypical cadherin 1 | 0.0368469 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0367532 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0364498 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0362719 |
| ANLN | anillin, actin binding protein | 0.0358672 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0351407 |
| RNF220 | ring finger protein 220 | 0.0343 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.0342375 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.034157 |
| KLF6 | Kruppel-like factor 6 | 0.0339909 |
| PKM | pyruvate kinase, muscle | 0.0339783 |
| RNF213 | ring finger protein 213 | 0.0337892 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0333502 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0332527 |
| ECT2 | epithelial cell transforming 2 | 0.0325346 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0315032 |
| ANXA5 | annexin A5 | 0.0309054 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0305383 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0304035 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0303673 |
| TPM3 | tropomyosin 3 | 0.0301217 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0300164 |
| RPL3 | ribosomal protein L3 | 0.0294709 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0293076 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0291617 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0290641 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0290148 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0287426 |
| HDAC9 | histone deacetylase 9 | 0.0285054 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0283304 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0279668 |
| FRMD5 | FERM domain containing 5 | 0.0278269 |
| TJP2 | tight junction protein 2 | 0.0277604 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272343 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.027218 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0267308 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0265658 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0263918 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0263671 |
| FRMD4A | FERM domain containing 4A | 0.0262311 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0261664 |
| ENO1 | enolase 1, (alpha) | 0.0261408 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0260124 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0259769 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0257268 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0256451 |
| EGFR | epidermal growth factor receptor | 0.0255001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.139421 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.118262 |
| TXNRD1 | thioredoxin reductase 1 | -0.112729 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112584 |
| FTL | ferritin, light polypeptide | -0.103332 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.103305 |
| ASPH | aspartate beta-hydroxylase | -0.0748804 |
| NDRG1 | N-myc downstream regulated 1 | -0.0737763 |
| GLIS3 | GLIS family zinc finger 3 | -0.0695659 |
| POTEF | POTE ankyrin domain family, member F | -0.0649131 |
| UBC | ubiquitin C | -0.0578296 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0564901 |
| RPS2 | ribosomal protein S2 | -0.048397 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.048328 |
| NOP58 | NOP58 ribonucleoprotein | -0.0482195 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0475652 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0435481 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0434053 |
| B2M | beta-2-microglobulin | -0.0423988 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0423771 |
| H3-3B | H3.3 histone B | -0.039918 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0388289 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0381869 |
| MTDH | metadherin | -0.0373374 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0372491 |
| EFHD2 | EF-hand domain family, member D2 | -0.0370097 |
| PTMA | prothymosin, alpha | -0.0367754 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366185 |
| CTSD | cathepsin D | -0.0362606 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.035964 |
| SRPK2 | SRSF protein kinase 2 | -0.0352287 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0350538 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0349218 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0348998 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.034895 |
| VEGFA | vascular endothelial growth factor A | -0.034878 |
| UBXN4 | UBX domain protein 4 | -0.0343613 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0343007 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0341679 |
| RPS13 | ribosomal protein S13 | -0.0340328 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0338452 |
| TUSC3 | tumor suppressor candidate 3 | -0.0335389 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0331216 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0327222 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0324254 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0322296 |
| TAOK1 | TAO kinase 1 | -0.0317714 |
| KYNU | kynureninase | -0.03158 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0314619 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0312649 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0310202 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0306769 |
| RPL38 | ribosomal protein L38 | -0.0306589 |
| RBM39 | RNA binding motif protein 39 | -0.030636 |
| RPL28 | ribosomal protein L28 | -0.0304451 |
| CDCP1 | CUB domain containing protein 1 | -0.0301779 |
| TAOK3 | TAO kinase 3 | -0.0301532 |
| RRBP1 | ribosome binding protein 1 | -0.0300008 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0299485 |
| RPL12 | ribosomal protein L12 | -0.0297826 |
| RHEB | Ras homolog enriched in brain | -0.0297823 |
| MYADM | myeloid-associated differentiation marker | -0.0296533 |
| GOLGB1 | golgin B1 | -0.0293091 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0292741 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0285186 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0279418 |
| UBN2 | ubinuclein 2 | -0.0276494 |
| HM13 | histocompatibility (minor) 13 | -0.0273797 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0272709 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0272703 |
| GOLM2 | golgi membrane protein 2 | -0.0270933 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0269861 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0266167 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0263914 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0263543 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0263151 |
| RAI14 | retinoic acid induced 14 | -0.0260199 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0259637 |
| MT2A | metallothionein 2A | -0.0254221 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0252432 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0251525 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0251519 |
| CP | ceruloplasmin (ferroxidase) | -0.0249635 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0248675 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0245711 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0245704 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0245452 |
| RPS19 | ribosomal protein S19 | -0.0244508 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0244051 |
| NUP98 | nucleoporin 98kDa | -0.0241417 |
| LOXL2 | lysyl oxidase-like 2 | -0.0238902 |
| TMSB10 | thymosin beta 10 | -0.0237209 |
| TMEM165 | transmembrane protein 165 | -0.0236559 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.023514 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0233868 |
| RPLP2 | ribosomal protein, large, P2 | -0.0232264 |
| SAA2 | serum amyloid A2 | -0.0231259 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0230416 |
| SETX | senataxin | -0.0230403 |
| SCFD2 | sec1 family domain containing 2 | -0.0230312 |
