| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.146348 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.143628 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.13529 |
| SPAG9 | sperm associated antigen 9 | 0.0981668 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0952114 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.093852 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0700146 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0679227 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0664197 |
| NUP58 | nucleoporin 58 | 0.0618549 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0612021 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0611409 |
| FMNL2 | formin-like 2 | 0.0610817 |
| FAM13A | family with sequence similarity 13, member A | 0.0600044 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0567525 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0565314 |
| FLNB | filamin B, beta | 0.0563576 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0539843 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0535658 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0520778 |
| PGK1 | phosphoglycerate kinase 1 | 0.051428 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0509166 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.049737 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0487024 |
| GOLGA4 | golgin A4 | 0.0483175 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0471222 |
| USP3 | ubiquitin specific peptidase 3 | 0.0452896 |
| HELZ | helicase with zinc finger | 0.0443642 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0414785 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0413202 |
| ECT2 | epithelial cell transforming 2 | 0.0393126 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0391569 |
| FA2H | fatty acid 2-hydroxylase | 0.0389816 |
| NGLY1 | N-glycanase 1 | 0.0389295 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0380707 |
| SET | SET nuclear proto-oncogene | 0.0376933 |
| NDRG1 | N-myc downstream regulated 1 | 0.0373809 |
| RPS2 | ribosomal protein S2 | 0.0364011 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0359728 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0355642 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0349069 |
| SRP54 | signal recognition particle 54kDa | 0.0347297 |
| MYOF | myoferlin | 0.0344817 |
| PRELID2 | PRELI domain containing 2 | 0.0344404 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0341182 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0340305 |
| ATP13A3 | ATPase type 13A3 | 0.0336504 |
| HDGF | hepatoma-derived growth factor | 0.0334661 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0333306 |
| ZNF292 | zinc finger protein 292 | 0.0332805 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0326424 |
| PTMA | prothymosin, alpha | 0.0325942 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0323174 |
| MKI67 | marker of proliferation Ki-67 | 0.0316728 |
| PCBP2 | poly(rC) binding protein 2 | 0.0313935 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0313311 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.030937 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.030504 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0301461 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0297221 |
| MSN | moesin | 0.0294427 |
| PYGL | phosphorylase, glycogen, liver | 0.0294424 |
| ANLN | anillin, actin binding protein | 0.0293912 |
| SEC24A | SEC24 family member A | 0.0290898 |
| NBAS | neuroblastoma amplified sequence | 0.0285784 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0283887 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.02803 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0276414 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0275177 |
| HIP1 | huntingtin interacting protein 1 | 0.0274387 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0269298 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0267851 |
| TPR | translocated promoter region, nuclear basket protein | 0.026413 |
| RNF24 | ring finger protein 24 | 0.0263628 |
| C1D | C1D nuclear receptor corepressor | 0.0260686 |
| MYO1B | myosin IB | 0.0254507 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254299 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0252886 |
| TPD52 | tumor protein D52 | 0.0251304 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0250894 |
| RASA2 | RAS p21 protein activator 2 | 0.0248836 |
| RAI1 | retinoic acid induced 1 | 0.0248684 |
| YEATS2 | YEATS domain containing 2 | 0.0247958 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0246457 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0246211 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0245962 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0242566 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0241966 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0241916 |
| PFN1 | profilin 1 | 0.0240142 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0236668 |
| SMAD3 | SMAD family member 3 | 0.0236645 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0234898 |
| CDC27 | cell division cycle 27 | 0.0234429 |
| KIF5B | kinesin family member 5B | 0.0232687 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0232463 |
| USP37 | ubiquitin specific peptidase 37 | 0.0232143 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0231053 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0231018 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0229013 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266413 |
| TMSB10 | thymosin beta 10 | -0.134372 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.119005 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.108525 |
| KYNU | kynureninase | -0.105756 |
| KRT81 | keratin 81, type II | -0.0792914 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0758797 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0732433 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0711704 |
| UBC | ubiquitin C | -0.0700192 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0692743 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0602118 |
| PDE10A | phosphodiesterase 10A | -0.0594802 |
| FTL | ferritin, light polypeptide | -0.0589002 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0588197 |
| OSMR | oncostatin M receptor | -0.0582346 |
| VCL | vinculin | -0.0566906 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0561706 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.055757 |
| EHBP1 | EH domain binding protein 1 | -0.0545657 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0527213 |
| MT2A | metallothionein 2A | -0.0519738 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0506174 |
| RPS6 | ribosomal protein S6 | -0.0495179 |
| MT1X | metallothionein 1X | -0.0491268 |
| AHNAK | AHNAK nucleoprotein | -0.0477398 |
| RPS24 | ribosomal protein S24 | -0.0474381 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0469931 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467628 |
| RPS16 | ribosomal protein S16 | -0.045623 |
| RPLP1 | ribosomal protein, large, P1 | -0.0451782 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0438963 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0430666 |
| ACTG1 | actin gamma 1 | -0.0423397 |
| TNS3 | tensin 3 | -0.0421102 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0418127 |
| BICC1 | BicC family RNA binding protein 1 | -0.0417895 |
| TXNRD1 | thioredoxin reductase 1 | -0.0416563 |
| EFNA5 | ephrin-A5 | -0.0412529 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0410073 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0399564 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0390072 |
| RPS19 | ribosomal protein S19 | -0.0388106 |
| RPL28 | ribosomal protein L28 | -0.0386828 |
| RPS27A | ribosomal protein S27a | -0.0370822 |
| GLIS3 | GLIS family zinc finger 3 | -0.0366765 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0361468 |
| PALLD | palladin, cytoskeletal associated protein | -0.0361096 |
| KRT7 | keratin 7, type II | -0.035666 |
| TPM1 | tropomyosin 1 (alpha) | -0.0356242 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0352507 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0338969 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0336268 |
| SP100 | SP100 nuclear antigen | -0.0329751 |
| RPL8 | ribosomal protein L8 | -0.0322113 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0321054 |
| EGR1 | early growth response 1 | -0.0318815 |
| RPLP2 | ribosomal protein, large, P2 | -0.0303813 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0298505 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0298082 |
| ACTN4 | actinin, alpha 4 | -0.0296212 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0295251 |
| POTEF | POTE ankyrin domain family, member F | -0.0293241 |
| ANXA2 | annexin A2 | -0.0292039 |
| GOLGB1 | golgin B1 | -0.0291944 |
| JMJD1C | jumonji domain containing 1C | -0.0280866 |
| RPL23 | ribosomal protein L23 | -0.0279891 |
| RPS5 | ribosomal protein S5 | -0.0278521 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0278245 |
| RPS23 | ribosomal protein S23 | -0.0277672 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0276706 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0275872 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.027436 |
| RPL38 | ribosomal protein L38 | -0.027372 |
| RNF213 | ring finger protein 213 | -0.0272702 |
| RPL32 | ribosomal protein L32 | -0.0272381 |
| RPS11 | ribosomal protein S11 | -0.0271827 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.026977 |
| NTN4 | netrin 4 | -0.0269592 |
| RPS13 | ribosomal protein S13 | -0.0269273 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0266483 |
| RSPO3 | R-spondin 3 | -0.0262288 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | -0.0260026 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0259675 |
| S100A10 | S100 calcium binding protein A10 | -0.0256599 |
| MYO9A | myosin IXA | -0.0255614 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0254963 |
| NRP1 | neuropilin 1 | -0.025424 |
| RPL19 | ribosomal protein L19 | -0.0252837 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0251746 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | -0.0249724 |
| FOXP1 | forkhead box P1 | -0.0249624 |
| RRBP1 | ribosome binding protein 1 | -0.0246342 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0245611 |
| RPS21 | ribosomal protein S21 | -0.0242655 |
| RHCG | Rh family, C glycoprotein | -0.0237254 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0237218 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0236824 |
| CUX1 | cut-like homeobox 1 | -0.0236703 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0236234 |
