| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MED13L | mediator complex subunit 13-like | 0.103403 |
| PRELID2 | PRELI domain containing 2 | 0.0911023 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0759249 |
| TMSB4X | thymosin beta 4, X-linked | 0.0734612 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0706756 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.070672 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0663721 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0639523 |
| RPL3 | ribosomal protein L3 | 0.0591722 |
| ZNF292 | zinc finger protein 292 | 0.0582924 |
| PDGFC | platelet derived growth factor C | 0.0580928 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0568181 |
| QKI | QKI, KH domain containing, RNA binding | 0.0561947 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0561664 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0561444 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0554691 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0543365 |
| ZNF608 | zinc finger protein 608 | 0.051396 |
| CENPF | centromere protein F, 350/400kDa | 0.0509221 |
| GSE1 | Gse1 coiled-coil protein | 0.0504057 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0501571 |
| NFIB | nuclear factor I/B | 0.0500095 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0496799 |
| OGA | O-GlcNAcase | 0.0495195 |
| H1-4 | H1.4 linker histone, cluster member | 0.0489197 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0462459 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0459524 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0446586 |
| HMGB2 | high mobility group box 2 | 0.0441253 |
| RPL4 | ribosomal protein L4 | 0.0438161 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0434873 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0434728 |
| SBF2 | SET binding factor 2 | 0.0432347 |
| ITGAV | integrin, alpha V | 0.0405889 |
| RBM33 | RNA binding motif protein 33 | 0.0395175 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0388457 |
| SEPTIN7 | septin 7 | 0.0379231 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0376491 |
| DIPK2A | divergent protein kinase domain 2A | 0.0376198 |
| FAM168A | family with sequence similarity 168, member A | 0.0375105 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0370138 |
| PHF3 | PHD finger protein 3 | 0.0368614 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0364171 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0361934 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0358403 |
| SPPL3 | signal peptide peptidase like 3 | 0.0356559 |
| FNIP1 | folliculin interacting protein 1 | 0.0355117 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0351973 |
| SET | SET nuclear proto-oncogene | 0.0346819 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0346109 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0341281 |
| MATR3 | matrin 3 | 0.0336923 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0335832 |
| ECT2 | epithelial cell transforming 2 | 0.0332271 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0332113 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0330252 |
| GPC6 | glypican 6 | 0.0329208 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0325772 |
| VEGFA | vascular endothelial growth factor A | 0.0324286 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0316826 |
| INSIG2 | insulin induced gene 2 | 0.0315059 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0313622 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0312108 |
| MYEF2 | myelin expression factor 2 | 0.0308339 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0307891 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0306877 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0304337 |
| ENAH | enabled homolog (Drosophila) | 0.030403 |
| USP3 | ubiquitin specific peptidase 3 | 0.0302188 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0301387 |
| SPAG5 | sperm associated antigen 5 | 0.0300561 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0299692 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0299507 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0293767 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0293083 |
| EXOC4 | exocyst complex component 4 | 0.0291836 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0289609 |
| NUP58 | nucleoporin 58 | 0.0287122 |
| ANLN | anillin, actin binding protein | 0.0286716 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0282687 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0282406 |
| CABIN1 | calcineurin binding protein 1 | 0.0281546 |
| PDS5B | PDS5 cohesin associated factor B | 0.0276579 |
| MB21D2 | Mab-21 domain containing 2 | 0.0274403 |
| CPNE8 | copine VIII | 0.0274343 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0272184 |
| YEATS2 | YEATS domain containing 2 | 0.0270074 |
| MANBA | mannosidase, beta A, lysosomal | 0.0268397 |
| TPD52 | tumor protein D52 | 0.0268138 |
| CD164 | CD164 molecule, sialomucin | 0.0266599 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0263084 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0258785 |
| CDK19 | cyclin-dependent kinase 19 | 0.0258063 |
| ATP11B | ATPase, class VI, type 11B | 0.0256806 |
| ARRDC3 | arrestin domain containing 3 | 0.025531 |
| ENO1 | enolase 1, (alpha) | 0.0250973 |
| SMAP1 | small ArfGAP 1 | 0.0247922 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0247513 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0246781 |
| ADM | adrenomedullin | 0.0244908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216133 |
| MEST | mesoderm specific transcript | -0.121868 |
| FTL | ferritin, light polypeptide | -0.0807079 |
| HMGA2 | high mobility group AT-hook 2 | -0.0804975 |
| SEPTIN11 | septin 11 | -0.0677693 |
| VIM | vimentin | -0.0672487 |
| NDRG1 | N-myc downstream regulated 1 | -0.0653532 |
| MGP | matrix Gla protein | -0.063396 |
| JMJD1C | jumonji domain containing 1C | -0.0619438 |
| MAP1B | microtubule-associated protein 1B | -0.055055 |
| IER3 | immediate early response 3 | -0.053849 |
| RPS6 | ribosomal protein S6 | -0.0535593 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0533896 |
| RPLP1 | ribosomal protein, large, P1 | -0.052374 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0518503 |
| EGR1 | early growth response 1 | -0.051572 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0513526 |
| RANBP17 | RAN binding protein 17 | -0.0511447 |
| KAZN | kazrin, periplakin interacting protein | -0.0508015 |
| ACTG1 | actin gamma 1 | -0.0500991 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0497148 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0495739 |
| CANX | calnexin | -0.0489087 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0486446 |
| TULP4 | tubby like protein 4 | -0.0478678 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0475823 |
| RPS8 | ribosomal protein S8 | -0.0464622 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.046365 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0462259 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0457279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0451811 |
| MT2A | metallothionein 2A | -0.0441379 |
| RSU1 | Ras suppressor protein 1 | -0.0423897 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0422906 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0422359 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0420357 |
| MTDH | metadherin | -0.0414648 |
| FBXO11 | F-box protein 11 | -0.0413472 |
| RPL35A | ribosomal protein L35a | -0.0408296 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0403072 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0401178 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0398388 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0394879 |
| HMGB1 | high mobility group box 1 | -0.0393785 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0390526 |
| TCF12 | transcription factor 12 | -0.0389581 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0388535 |
| RPS29 | ribosomal protein S29 | -0.0376167 |
| E2F3 | E2F transcription factor 3 | -0.0375405 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0371023 |
| VCL | vinculin | -0.0369479 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0364581 |
| LDHA | lactate dehydrogenase A | -0.0361419 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0355765 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.035462 |
| BPTF | bromodomain PHD finger transcription factor | -0.0353615 |
| INTS6 | integrator complex subunit 6 | -0.0353316 |
| NF1 | neurofibromin 1 | -0.0346467 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0345181 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0339248 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0337554 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0334686 |
| UBE3C | ubiquitin protein ligase E3C | -0.0332448 |
| COL1A2 | collagen, type I, alpha 2 | -0.0325447 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0320672 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0320577 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0320067 |
| ATP11A | ATPase, class VI, type 11A | -0.0319803 |
| CDK13 | cyclin-dependent kinase 13 | -0.0319725 |
| S100A10 | S100 calcium binding protein A10 | -0.0317695 |
| TBCA | tubulin folding cofactor A | -0.0313209 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0313074 |
| RPS23 | ribosomal protein S23 | -0.0312048 |
| HMGA1 | high mobility group AT-hook 1 | -0.031192 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0308048 |
| CCNI | cyclin I | -0.030542 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0302055 |
| RPS25 | ribosomal protein S25 | -0.0301649 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0299461 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.029893 |
| RPL28 | ribosomal protein L28 | -0.0297522 |
| COG5 | component of oligomeric golgi complex 5 | -0.0295611 |
| RPLP0 | ribosomal protein, large, P0 | -0.0294298 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0294101 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0294079 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.029322 |
| CADM2 | cell adhesion molecule 2 | -0.0291753 |
| GNAS | GNAS complex locus | -0.0289287 |
| PARD3 | par-3 family cell polarity regulator | -0.0289115 |
| RPL38 | ribosomal protein L38 | -0.0286797 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0285621 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0284624 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0281795 |
| CTBP2 | C-terminal binding protein 2 | -0.0281154 |
| RPS13 | ribosomal protein S13 | -0.027855 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.027331 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0272228 |
| PRKCE | protein kinase C, epsilon | -0.0270765 |
| SHROOM3 | shroom family member 3 | -0.027049 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0270039 |
