| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.213189 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.155083 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140932 |
| PLEC | plectin | 0.134138 |
| LAMB3 | laminin, beta 3 | 0.0977793 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0924704 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0883072 |
| ITGA6 | integrin, alpha 6 | 0.0853624 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0806713 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0794025 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0702427 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0689841 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0689788 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0680471 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.065043 |
| LAMC2 | laminin, gamma 2 | 0.0612227 |
| PGK1 | phosphoglycerate kinase 1 | 0.0610657 |
| FAM13A | family with sequence similarity 13, member A | 0.0601866 |
| MUC17 | mucin 17, cell surface associated | 0.0576523 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0569909 |
| DSPP | dentin sialophosphoprotein | 0.0568192 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0527727 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0515124 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0513645 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0507447 |
| ATP13A3 | ATPase type 13A3 | 0.0495918 |
| CAPRIN2 | caprin family member 2 | 0.0495323 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0486853 |
| FMNL2 | formin-like 2 | 0.0444479 |
| RPS2 | ribosomal protein S2 | 0.0423149 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0414694 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0394625 |
| SLK | STE20-like kinase | 0.0386058 |
| FA2H | fatty acid 2-hydroxylase | 0.0384348 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0379094 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.037808 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0355391 |
| SET | SET nuclear proto-oncogene | 0.0349087 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0348537 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0337695 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0336407 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0335725 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0329749 |
| VCAN | versican | 0.0324864 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.032443 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0322488 |
| EFNA5 | ephrin-A5 | 0.0321397 |
| NDRG1 | N-myc downstream regulated 1 | 0.0301664 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0294072 |
| NCKAP1 | NCK-associated protein 1 | 0.0293228 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0293203 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0286238 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0283693 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0283407 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0277295 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.027554 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0273506 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0270344 |
| RPS12 | ribosomal protein S12 | 0.02559 |
| HPCAL1 | hippocalcin-like 1 | 0.025565 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0252284 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0252017 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0251836 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0250103 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.024458 |
| PLEK2 | pleckstrin 2 | 0.0244506 |
| XPO1 | exportin 1 | 0.0244135 |
| FAM107B | family with sequence similarity 107, member B | 0.0242107 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0240738 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0238366 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0235253 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0232693 |
| PRELID2 | PRELI domain containing 2 | 0.0232509 |
| NUP58 | nucleoporin 58 | 0.0231025 |
| RPL3 | ribosomal protein L3 | 0.0224787 |
| FERMT1 | fermitin family member 1 | 0.0222708 |
| SLTM | SAFB-like, transcription modulator | 0.0219273 |
| AFDN | afadin, adherens junction formation factor | 0.0218925 |
| RPL4 | ribosomal protein L4 | 0.0216043 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0214837 |
| CCNY | cyclin Y | 0.0214728 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0213156 |
| FNBP1L | formin binding protein 1-like | 0.021058 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0209459 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0208137 |
| MKI67 | marker of proliferation Ki-67 | 0.0207371 |
| HDGF | hepatoma-derived growth factor | 0.0205003 |
| APP | amyloid beta (A4) precursor protein | 0.0204543 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0201801 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0200515 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0199577 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0198327 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0198276 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0194462 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.019421 |
| CDCP1 | CUB domain containing protein 1 | 0.0192962 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0192381 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0192363 |
| RNF149 | ring finger protein 149 | 0.0189715 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | 0.0188768 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25357 |
| UBC | ubiquitin C | -0.179893 |
| TMSB10 | thymosin beta 10 | -0.172141 |
| POTEF | POTE ankyrin domain family, member F | -0.145807 |
| TXNRD1 | thioredoxin reductase 1 | -0.136762 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.131182 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.107956 |
| S100A10 | S100 calcium binding protein A10 | -0.0979993 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0926124 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0878212 |
| HMGA1 | high mobility group AT-hook 1 | -0.0809365 |
| EGR1 | early growth response 1 | -0.0797206 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0792851 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0643619 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0623556 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0623089 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0607341 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0549325 |
| FBXO11 | F-box protein 11 | -0.0536123 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523499 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0520284 |
| SQSTM1 | sequestosome 1 | -0.0474881 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0472843 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0471643 |
| ARF4 | ADP-ribosylation factor 4 | -0.046927 |
| EGFR | epidermal growth factor receptor | -0.0462673 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0461269 |
| ANXA2 | annexin A2 | -0.0450132 |
| RASAL2 | RAS protein activator like 2 | -0.0440488 |
| TAOK3 | TAO kinase 3 | -0.0440107 |
| RHOA | ras homolog family member A | -0.0437801 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0433294 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0430052 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0429795 |
| FTL | ferritin, light polypeptide | -0.0427156 |
| AHNAK | AHNAK nucleoprotein | -0.0423072 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0422527 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0417698 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0414531 |
| RPL8 | ribosomal protein L8 | -0.0414146 |
| PTMA | prothymosin, alpha | -0.0413124 |
| CALU | calumenin | -0.0412149 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0411622 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0410798 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0405844 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0404082 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.040119 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0398061 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0396651 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0395135 |
| TXNIP | thioredoxin interacting protein | -0.0393688 |
| OXSR1 | oxidative stress responsive 1 | -0.0390341 |
| CDK13 | cyclin-dependent kinase 13 | -0.0386876 |
| EZR | ezrin | -0.0386312 |
| RPS21 | ribosomal protein S21 | -0.0386243 |
| LOC112694756 | uncharaterized LOC112694756 | -0.038464 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0382958 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0379753 |
| LMO7 | LIM domain 7 | -0.0378688 |
| NOP58 | NOP58 ribonucleoprotein | -0.0377343 |
| FUS | FUS RNA binding protein | -0.0373765 |
| VIM | vimentin | -0.0372986 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0371846 |
| RBM39 | RNA binding motif protein 39 | -0.0364845 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0361225 |
| DSG2 | desmoglein 2 | -0.0360214 |
| GOLGB1 | golgin B1 | -0.0354831 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.035211 |
| HDLBP | high density lipoprotein binding protein | -0.0351677 |
| PMM2 | phosphomannomutase 2 | -0.0349384 |
| RPS13 | ribosomal protein S13 | -0.0348618 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0346969 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0345796 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.034536 |
| VMP1 | vacuole membrane protein 1 | -0.0339226 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0335619 |
| PCBP2 | poly(rC) binding protein 2 | -0.0334658 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0333953 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0332566 |
| RPS27A | ribosomal protein S27a | -0.0327118 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0325948 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0324601 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321634 |
| WASF2 | WAS protein family, member 2 | -0.0321461 |
| ATG12 | autophagy related 12 | -0.0321076 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0315794 |
| CD2AP | CD2-associated protein | -0.031456 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0313668 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0308963 |
| TJP1 | tight junction protein 1 | -0.030792 |
| RPLP1 | ribosomal protein, large, P1 | -0.030176 |
| EMP1 | epithelial membrane protein 1 | -0.0300166 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0293458 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.029332 |
| S100A6 | S100 calcium binding protein A6 | -0.0292636 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0290925 |
| SIK3 | SIK family kinase 3 | -0.0290665 |
| PERP | PERP, TP53 apoptosis effector | -0.0286682 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0285054 |
| TMEM263 | transmembrane protein 263 | -0.0283063 |
