| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.10756 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.102284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0787033 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0786714 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0678308 |
| TMSB4X | thymosin beta 4, X-linked | 0.0644503 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0595616 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0588797 |
| SET | SET nuclear proto-oncogene | 0.0536303 |
| PTMA | prothymosin, alpha | 0.0513826 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0508698 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0468918 |
| FAM13A | family with sequence similarity 13, member A | 0.045297 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.044546 |
| PGK1 | phosphoglycerate kinase 1 | 0.0425723 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0417836 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.041231 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.04036 |
| CEP250 | centrosomal protein 250kDa | 0.040168 |
| TMEM123 | transmembrane protein 123 | 0.0387646 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0383727 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0379476 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0378999 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0365534 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0363586 |
| KIF16B | kinesin family member 16B | 0.0353353 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0342212 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0340584 |
| DSPP | dentin sialophosphoprotein | 0.0338711 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0336379 |
| GSE1 | Gse1 coiled-coil protein | 0.0332261 |
| TPM3 | tropomyosin 3 | 0.032707 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0320339 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0313862 |
| ZNF292 | zinc finger protein 292 | 0.0311254 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306274 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.030617 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0292845 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0284433 |
| CALR | calreticulin | 0.0282335 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0281875 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0280201 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0278843 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0270776 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0264638 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0264451 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0260927 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0252426 |
| HMGB2 | high mobility group box 2 | 0.0252205 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0249071 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246959 |
| RAB6A | RAB6A, member RAS oncogene family | 0.024357 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239785 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0239287 |
| ECT2 | epithelial cell transforming 2 | 0.0239256 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0237915 |
| FADS2 | fatty acid desaturase 2 | 0.0236366 |
| CCNY | cyclin Y | 0.0236001 |
| FNBP1L | formin binding protein 1-like | 0.0235762 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0235643 |
| TPD52 | tumor protein D52 | 0.0233067 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0232999 |
| PLEC | plectin | 0.0232912 |
| EFNA1 | ephrin-A1 | 0.0229111 |
| RPL3 | ribosomal protein L3 | 0.0228995 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0228354 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0225155 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0225132 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0224084 |
| YEATS2 | YEATS domain containing 2 | 0.0223839 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0223683 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0220053 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0218106 |
| CCDC6 | coiled-coil domain containing 6 | 0.0216788 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0215304 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0212088 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0210169 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0209015 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0208066 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0207557 |
| NBAS | neuroblastoma amplified sequence | 0.020484 |
| USP53 | ubiquitin specific peptidase 53 | 0.0204705 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0203555 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0201969 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0201735 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0201336 |
| LRRC1 | leucine rich repeat containing 1 | 0.0195617 |
| RTN4 | reticulon 4 | 0.0195196 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0194904 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0194398 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0192687 |
| ZFHX3 | zinc finger homeobox 3 | 0.0192159 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0190032 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0189581 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0188788 |
| NUP58 | nucleoporin 58 | 0.0188432 |
| KRT8 | keratin 8, type II | 0.0186654 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0186504 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0186462 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0184951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CATSPERB | catsper channel auxiliary subunit beta | -0.175444 |
| CDK12 | cyclin-dependent kinase 12 | -0.173072 |
| RPL19 | ribosomal protein L19 | -0.0982921 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.086925 |
| MT2A | metallothionein 2A | -0.0807005 |
| INTS6 | integrator complex subunit 6 | -0.0801801 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0785931 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0782991 |
| S100A8 | S100 calcium binding protein A8 | -0.0729509 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0711542 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0639509 |
| S100A9 | S100 calcium binding protein A9 | -0.0609879 |
| ASPH | aspartate beta-hydroxylase | -0.0566801 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0521967 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0520985 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0505384 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0503686 |
| GOLGB1 | golgin B1 | -0.0485199 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0482408 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0463066 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0458037 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0452327 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0448192 |
| SMYD3 | SET and MYND domain containing 3 | -0.0447434 |
| NTN4 | netrin 4 | -0.0439685 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0436588 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.043448 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0432325 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0429823 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0423747 |
| OSMR | oncostatin M receptor | -0.0402394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0394074 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0393633 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0380057 |
| MMP24OS | MMP24 opposite strand | -0.0377117 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0373234 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0371275 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0363808 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0358271 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0353895 |
| NABP1 | nucleic acid binding protein 1 | -0.0353005 |
| SEPTIN9 | septin 9 | -0.0352697 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0349885 |
| CCND1 | cyclin D1 | -0.0349827 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0347165 |
| MYO1D | myosin ID | -0.0345892 |
| STXBP4 | syntaxin binding protein 4 | -0.0343752 |
| TC2N | tandem C2 domains, nuclear | -0.0342233 |
| KRT86 | keratin 86, type II | -0.0341805 |
| ZNF217 | zinc finger protein 217 | -0.0341725 |
| GLCCI1 | glucocorticoid induced 1 | -0.0341682 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0336465 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0336004 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.033565 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0334869 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0333375 |
| RPL23 | ribosomal protein L23 | -0.033057 |
| SP100 | SP100 nuclear antigen | -0.0320679 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.031907 |
| PRKCA | protein kinase C, alpha | -0.0318079 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0314358 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0313641 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0313487 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0311735 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0311698 |
| S100A7 | S100 calcium binding protein A7 | -0.0305023 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0304661 |
| ATXN1 | ataxin 1 | -0.0288226 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0287545 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0287033 |
| EGFR | epidermal growth factor receptor | -0.0285451 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0283413 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0283228 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0280721 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0280246 |
| PLSCR2 | phospholipid scramblase 2 | -0.0278007 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0277378 |
| S100A14 | S100 calcium binding protein A14 | -0.0276854 |
| BPTF | bromodomain PHD finger transcription factor | -0.0270926 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0270611 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0263941 |
| MCL1 | myeloid cell leukemia 1 | -0.0260553 |
| SMAD3 | SMAD family member 3 | -0.0259789 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0255871 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0253069 |
| GRHL2 | grainyhead-like 2 (Drosophila) | -0.0252797 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.025204 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0251482 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0251378 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0250917 |
| MIPOL1 | mirror-image polydactyly 1 | -0.025028 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0249901 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0248807 |
| JMJD1C | jumonji domain containing 1C | -0.0248044 |
| CUX1 | cut-like homeobox 1 | -0.0242877 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0241203 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0240256 |
| PFDN4 | prefoldin subunit 4 | -0.0239937 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.023974 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0239249 |
