| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.103512 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0864339 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.085806 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0752148 |
| NUP58 | nucleoporin 58 | 0.07465 |
| FMNL2 | formin-like 2 | 0.0659825 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0495184 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0485916 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0464337 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0456975 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0445774 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.044165 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0435292 |
| NEBL | nebulette | 0.042418 |
| ZNF292 | zinc finger protein 292 | 0.0400893 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.039557 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.038664 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0372996 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0372014 |
| HELZ | helicase with zinc finger | 0.0370741 |
| PTK2 | protein tyrosine kinase 2 | 0.0367641 |
| TRIM33 | tripartite motif containing 33 | 0.0362591 |
| RFX7 | regulatory factor X, 7 | 0.0355349 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0352655 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0352466 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0349512 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0338903 |
| PTCH1 | patched 1 | 0.0329812 |
| TPD52 | tumor protein D52 | 0.031612 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0315024 |
| TOX | thymocyte selection-associated high mobility group box | 0.031093 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0307415 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0303388 |
| YEATS2 | YEATS domain containing 2 | 0.0303353 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0298579 |
| RPS2 | ribosomal protein S2 | 0.0291876 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0291269 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0290274 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0280306 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0277775 |
| PRELID2 | PRELI domain containing 2 | 0.0274447 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0273812 |
| CABIN1 | calcineurin binding protein 1 | 0.0273401 |
| PCM1 | pericentriolar material 1 | 0.0272381 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0272359 |
| TENM3 | teneurin transmembrane protein 3 | 0.0267457 |
| KIF1B | kinesin family member 1B | 0.0266941 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0264236 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0263983 |
| RPL11 | ribosomal protein L11 | 0.0259187 |
| PNN | pinin, desmosome associated protein | 0.0257732 |
| FAM117B | family with sequence similarity 117, member B | 0.0255008 |
| HMGA1 | high mobility group AT-hook 1 | 0.0252688 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0251529 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.0250197 |
| TBK1 | TANK-binding kinase 1 | 0.0250072 |
| RPL3 | ribosomal protein L3 | 0.0249356 |
| VEGFC | vascular endothelial growth factor C | 0.0248594 |
| HDGF | hepatoma-derived growth factor | 0.0248032 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.024801 |
| SET | SET nuclear proto-oncogene | 0.0245088 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0242802 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0242559 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0242426 |
| CASC3 | cancer susceptibility candidate 3 | 0.0241878 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0240887 |
| FOXO3 | forkhead box O3 | 0.0239563 |
| ZFP64 | ZFP64 zinc finger protein | 0.023939 |
| MAPT | microtubule-associated protein tau | 0.0238464 |
| TNPO3 | transportin 3 | 0.0238392 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0238235 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237906 |
| BRD4 | bromodomain containing 4 | 0.023711 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.023611 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0229939 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0227703 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0227166 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0225001 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0224018 |
| FAM168A | family with sequence similarity 168, member A | 0.022263 |
| ATRN | attractin | 0.0222043 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.022176 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0221004 |
| CDC73 | cell division cycle 73 | 0.0219957 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0218895 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.021731 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0214311 |
| DDHD1 | DDHD domain containing 1 | 0.0213727 |
| KIAA1958 | KIAA1958 | 0.0212175 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0210034 |
| MEMO1 | mediator of cell motility 1 | 0.0209836 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0207853 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0207794 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0207794 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0207081 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0206369 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0205847 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0204367 |
| DYM | dymeclin | 0.0204129 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0204097 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.213078 |
| UBC | ubiquitin C | -0.151177 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.106099 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0972622 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0824785 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0782227 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.076003 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0700102 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0698009 |
| PTMA | prothymosin, alpha | -0.0659078 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0644483 |
| CANX | calnexin | -0.0621785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.061719 |
| LDHA | lactate dehydrogenase A | -0.0612158 |
| ENO1 | enolase 1, (alpha) | -0.0590142 |
| HMGB1 | high mobility group box 1 | -0.0581178 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0576191 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0567022 |
| H1-0 | H1.0 linker histone | -0.0565335 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0564753 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0562533 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0538221 |
| RPS27A | ribosomal protein S27a | -0.0532021 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0516691 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.051278 |
| RIGI | RNA sensor RIG-I | -0.0486389 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0476178 |
| CADM2 | cell adhesion molecule 2 | -0.0457663 |
| ZNF608 | zinc finger protein 608 | -0.0455854 |
| VMP1 | vacuole membrane protein 1 | -0.0438098 |
| JUN | jun proto-oncogene | -0.0432634 |
| B2M | beta-2-microglobulin | -0.0432383 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0423534 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0420188 |
| RPL12 | ribosomal protein L12 | -0.0420186 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0414883 |
| OGA | O-GlcNAcase | -0.0407835 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.040108 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0391633 |
| RPL23 | ribosomal protein L23 | -0.0388988 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.038706 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0385451 |
| HDLBP | high density lipoprotein binding protein | -0.0381863 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0379417 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0369378 |
| TMSB10 | thymosin beta 10 | -0.0365594 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0364821 |
| TUBB | tubulin, beta class I | -0.0357025 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0356699 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0340979 |
| ZNF217 | zinc finger protein 217 | -0.0340669 |
| RPL32 | ribosomal protein L32 | -0.0326106 |
| LOC112694756 | uncharaterized LOC112694756 | -0.032507 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0323543 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0322077 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.032037 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319487 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0318705 |
| FUS | FUS RNA binding protein | -0.0318471 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0316701 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.031661 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.031117 |
| R3HDM1 | R3H domain containing 1 | -0.0310511 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0309385 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0308325 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0307701 |
| RPL34 | ribosomal protein L34 | -0.0305075 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0304779 |
| HHIP | hedgehog interacting protein | -0.0304566 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0299078 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0298477 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0294871 |
| CCDC47 | coiled-coil domain containing 47 | -0.029474 |
| RPS24 | ribosomal protein S24 | -0.0294075 |
| RPS4X | ribosomal protein S4, X-linked | -0.0292057 |
| NF1 | neurofibromin 1 | -0.0290122 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.028605 |
| CALU | calumenin | -0.0285133 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0284875 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0284707 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0284225 |
| MED12L | mediator complex subunit 12-like | -0.0282654 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0282277 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0281603 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0279416 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0279026 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0278345 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0276186 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.0275606 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0275437 |
| ANXA2 | annexin A2 | -0.0267904 |
| ACTG1 | actin gamma 1 | -0.0267811 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0266873 |
| ASPH | aspartate beta-hydroxylase | -0.0266005 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.026305 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0262257 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0262159 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0261969 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0259661 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0259039 |
