| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.14548 |
| FN1 | fibronectin 1 | 0.129082 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.101615 |
| PGK1 | phosphoglycerate kinase 1 | 0.0999532 |
| ASPH | aspartate beta-hydroxylase | 0.0980509 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0949699 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0932355 |
| ENO1 | enolase 1, (alpha) | 0.0931734 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0920146 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.087182 |
| CD109 | CD109 molecule | 0.084719 |
| CDC73 | cell division cycle 73 | 0.0840715 |
| FMNL2 | formin-like 2 | 0.0827656 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0808292 |
| NUP58 | nucleoporin 58 | 0.0722218 |
| VGF | VGF nerve growth factor inducible | 0.0716532 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0707377 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0705958 |
| PKM | pyruvate kinase, muscle | 0.0702219 |
| PRELID2 | PRELI domain containing 2 | 0.0689569 |
| DCT | dopachrome tautomerase | 0.0658811 |
| COPA | coatomer protein complex, subunit alpha | 0.0627739 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.06254 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0613026 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0599665 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0595561 |
| DST | dystonin | 0.0591467 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0582733 |
| TMEM178B | transmembrane protein 178B | 0.0579143 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0564687 |
| PHF21A | PHD finger protein 21A | 0.0549929 |
| FBXO7 | F-box protein 7 | 0.0549119 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0510957 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0509859 |
| LDHA | lactate dehydrogenase A | 0.0507068 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0502563 |
| RPL3 | ribosomal protein L3 | 0.0497114 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0486212 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0479968 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0477211 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0455688 |
| NAV2 | neuron navigator 2 | 0.0452967 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0450489 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0448462 |
| ARRDC3 | arrestin domain containing 3 | 0.0445896 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0440198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0433669 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.042832 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0408713 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0406854 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0405647 |
| ANXA5 | annexin A5 | 0.0404073 |
| TPR | translocated promoter region, nuclear basket protein | 0.040305 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0394988 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0389125 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0387887 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.038104 |
| SFTPA2 | surfactant protein A2 | 0.0379444 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0379402 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0378938 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0375151 |
| CTTNBP2 | cortactin binding protein 2 | 0.0369223 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0368482 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0367988 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0366039 |
| KLF10 | Kruppel-like factor 10 | 0.0363405 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0361952 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0357677 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0356623 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0349496 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0347894 |
| RNF145 | ring finger protein 145 | 0.0347081 |
| SETBP1 | SET binding protein 1 | 0.0341676 |
| CALR | calreticulin | 0.0338822 |
| TPI1 | triosephosphate isomerase 1 | 0.0334492 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.032326 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0319579 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0319376 |
| MKI67 | marker of proliferation Ki-67 | 0.0319024 |
| ZNF292 | zinc finger protein 292 | 0.0318378 |
| CABIN1 | calcineurin binding protein 1 | 0.0318188 |
| CD44 | CD44 molecule (Indian blood group) | 0.0311544 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0311529 |
| FRMD6 | FERM domain containing 6 | 0.0309462 |
| RPL4 | ribosomal protein L4 | 0.0306339 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.030565 |
| XPO1 | exportin 1 | 0.0303296 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0303075 |
| SEPTIN9 | septin 9 | 0.0302807 |
| NBAS | neuroblastoma amplified sequence | 0.0302584 |
| MKRN1 | makorin ring finger protein 1 | 0.0302338 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0299599 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0293766 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0293132 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0292307 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0289344 |
| AHR | aryl hydrocarbon receptor | 0.0287019 |
| MYOF | myoferlin | 0.0286475 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0285308 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0284133 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.385916 |
| EGR1 | early growth response 1 | -0.0970787 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0795001 |
| FMN1 | formin 1 | -0.0754708 |
| NDRG1 | N-myc downstream regulated 1 | -0.0740525 |
| IER3 | immediate early response 3 | -0.0694354 |
| GDF15 | growth differentiation factor 15 | -0.0692802 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0691267 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0687039 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0617824 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0589344 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0561089 |
| GPC6 | glypican 6 | -0.0540755 |
| NLGN1 | neuroligin 1 | -0.0538766 |
| RPLP1 | ribosomal protein, large, P1 | -0.0493786 |
| FUS | FUS RNA binding protein | -0.0451589 |
| ACTG1 | actin gamma 1 | -0.0450254 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0447038 |
| NPR2 | natriuretic peptide receptor 2 | -0.0428444 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0422408 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.041073 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0396496 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0381465 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0375235 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0374937 |
| FTL | ferritin, light polypeptide | -0.0368808 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0365201 |
| LRRC23 | leucine rich repeat containing 23 | -0.0362924 |
| MYO1E | myosin IE | -0.0362545 |
| SEC24A | SEC24 family member A | -0.0356814 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0356214 |
| ATF6 | activating transcription factor 6 | -0.0349318 |
| FRMD4A | FERM domain containing 4A | -0.0347709 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0339557 |
| VCL | vinculin | -0.033839 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0334248 |
| TNNC1 | troponin C type 1 (slow) | -0.0334184 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0331672 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.033145 |
| MACROD2 | MACRO domain containing 2 | -0.0326679 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0320103 |
| PAX3 | paired box 3 | -0.0312935 |
| DENND1A | DENN/MADD domain containing 1A | -0.0297294 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0296592 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0295516 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0293722 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0291765 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0289425 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0288398 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0288226 |
| CUX1 | cut-like homeobox 1 | -0.0280004 |
| PTCHD4 | patched domain containing 4 | -0.0276791 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0272399 |
| RUNX1 | runt-related transcription factor 1 | -0.0271475 |
| FRMD5 | FERM domain containing 5 | -0.0270405 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0266803 |
| RHEB | Ras homolog enriched in brain | -0.026559 |
| SCFD2 | sec1 family domain containing 2 | -0.0264628 |
| GTF2B | general transcription factor IIB | -0.0263183 |
| RPL35A | ribosomal protein L35a | -0.0263131 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0258539 |
| OSMR | oncostatin M receptor | -0.0256203 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.02508 |
| NBEAL1 | neurobeachin-like 1 | -0.0247762 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0245623 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.024524 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0243704 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0243457 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0241168 |
| HMCN1 | hemicentin 1 | -0.0238756 |
| TLE4 | transducin-like enhancer of split 4 | -0.0236296 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0233628 |
| JUN | jun proto-oncogene | -0.023336 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.02327 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.022862 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0224498 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0222629 |
| CDK14 | cyclin-dependent kinase 14 | -0.0221147 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0218792 |
| NRCAM | neuronal cell adhesion molecule | -0.0218564 |
| GOLGB1 | golgin B1 | -0.0218057 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0214945 |
| TFRC | transferrin receptor | -0.0214907 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0213363 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0209997 |
| RLF | rearranged L-myc fusion | -0.0207551 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.020739 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0206314 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0205657 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0204742 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0202813 |
| SMYD3 | SET and MYND domain containing 3 | -0.0202395 |
| CDH19 | cadherin 19, type 2 | -0.0201814 |
| INTS6 | integrator complex subunit 6 | -0.0197835 |
| EHBP1 | EH domain binding protein 1 | -0.0197592 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0197083 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0195903 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0194783 |
| OPHN1 | oligophrenin 1 | -0.0193851 |
| ATXN7L1 | ataxin 7-like 1 | -0.0192119 |
