| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.140878 |
| PGK1 | phosphoglycerate kinase 1 | 0.13967 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.138916 |
| TMSB4X | thymosin beta 4, X-linked | 0.12932 |
| DTNA | dystrobrevin, alpha | 0.124007 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.123363 |
| ASPH | aspartate beta-hydroxylase | 0.121605 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.103571 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0939523 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0918438 |
| RPL4 | ribosomal protein L4 | 0.0862148 |
| LAMB3 | laminin, beta 3 | 0.0849235 |
| HPCAL1 | hippocalcin-like 1 | 0.0845386 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0762076 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0755825 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0747683 |
| FAM13A | family with sequence similarity 13, member A | 0.0692899 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0691211 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0677113 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0668344 |
| ENO1 | enolase 1, (alpha) | 0.0658005 |
| MEF2A | myocyte enhancer factor 2A | 0.0656518 |
| ANKRD11 | ankyrin repeat domain 11 | 0.065607 |
| ACTG1 | actin gamma 1 | 0.0629724 |
| ANXA2 | annexin A2 | 0.0622032 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.061678 |
| CCNY | cyclin Y | 0.0603957 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0593949 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0578828 |
| FLNA | filamin A, alpha | 0.0571556 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0558947 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0536548 |
| KRT8 | keratin 8, type II | 0.0530184 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0516191 |
| FNBP1L | formin binding protein 1-like | 0.0514976 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0513947 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0512667 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0504793 |
| NUP58 | nucleoporin 58 | 0.0491881 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0485046 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0480821 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0479875 |
| LAMC2 | laminin, gamma 2 | 0.0477351 |
| FOSL1 | FOS-like antigen 1 | 0.0466533 |
| RPL23 | ribosomal protein L23 | 0.0458488 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0457204 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0454918 |
| SDC4 | syndecan 4 | 0.0453961 |
| PLEC | plectin | 0.0441619 |
| CALR | calreticulin | 0.043848 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0420746 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0411255 |
| RPL35A | ribosomal protein L35a | 0.0410055 |
| RACK1 | receptor for activated C kinase 1 | 0.0392647 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0389908 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0388994 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.038882 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0388057 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0386688 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0384213 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0382479 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0381194 |
| APP | amyloid beta (A4) precursor protein | 0.037772 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0375179 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0371457 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0367625 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0364829 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0362496 |
| FLNB | filamin B, beta | 0.036157 |
| RPS8 | ribosomal protein S8 | 0.0360398 |
| HELZ | helicase with zinc finger | 0.0358333 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0357781 |
| ACTN1 | actinin, alpha 1 | 0.0356027 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0354203 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0354047 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0353208 |
| ZNF292 | zinc finger protein 292 | 0.0349605 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0341988 |
| PLAU | plasminogen activator, urokinase | 0.0336913 |
| CLIC1 | chloride intracellular channel 1 | 0.0335123 |
| RPS17 | ribosomal protein S17 | 0.033468 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0329841 |
| LAMA4 | laminin, alpha 4 | 0.0327216 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0326979 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0326322 |
| RPS12 | ribosomal protein S12 | 0.0322513 |
| NPTN | neuroplastin | 0.0322022 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0321421 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0321053 |
| YBX1 | Y box binding protein 1 | 0.032 |
| MYO1B | myosin IB | 0.0318344 |
| FAM162A | family with sequence similarity 162, member A | 0.0313077 |
| KRT18 | keratin 18, type I | 0.0313077 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0307956 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0307588 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0306382 |
| PEG10 | paternally expressed 10 | 0.0305938 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.029875 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.029687 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0295426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.212715 |
| NDRG1 | N-myc downstream regulated 1 | -0.0875875 |
| LMO7 | LIM domain 7 | -0.0832586 |
| TXNIP | thioredoxin interacting protein | -0.0816066 |
| PTMA | prothymosin, alpha | -0.077716 |
| UBC | ubiquitin C | -0.077673 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0739913 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0684372 |
| CD2AP | CD2-associated protein | -0.0666461 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0663594 |
| GOLGB1 | golgin B1 | -0.0537881 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0529838 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0492845 |
| CDCP1 | CUB domain containing protein 1 | -0.0480961 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0463226 |
| MT1X | metallothionein 1X | -0.0450907 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0446405 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0427811 |
| RPS6 | ribosomal protein S6 | -0.041765 |
| MYO1E | myosin IE | -0.0412996 |
| SYNRG | synergin, gamma | -0.0412582 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0407585 |
| BRD2 | bromodomain containing 2 | -0.0404459 |
| DSG2 | desmoglein 2 | -0.0397117 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.038899 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0378311 |
| VEGFA | vascular endothelial growth factor A | -0.0375192 |
| FAM3C | family with sequence similarity 3, member C | -0.0374515 |
| CSTB | cystatin B (stefin B) | -0.0372143 |
| MT2A | metallothionein 2A | -0.0370766 |
| CDK12 | cyclin-dependent kinase 12 | -0.0365883 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0365103 |
| EGR1 | early growth response 1 | -0.0365045 |
| IER3 | immediate early response 3 | -0.0361641 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0349237 |
| CLINT1 | clathrin interactor 1 | -0.0344979 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0342244 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0339218 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0338265 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0337801 |
| MX1 | MX dynamin-like GTPase 1 | -0.0333051 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0328172 |
| CCNL1 | cyclin L1 | -0.0327744 |
| RPS2 | ribosomal protein S2 | -0.0327223 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0324755 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0323047 |
| TMC5 | transmembrane channel-like 5 | -0.0322138 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0321141 |
| RBM39 | RNA binding motif protein 39 | -0.0320473 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0316046 |
| TMEM165 | transmembrane protein 165 | -0.0316002 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0313996 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0313817 |
| ATOSA | atos homolog A | -0.0313123 |
| JMJD1C | jumonji domain containing 1C | -0.0310999 |
| NRP1 | neuropilin 1 | -0.0305944 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0305605 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0305027 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0304405 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0302926 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0301941 |
| TAOK3 | TAO kinase 3 | -0.0301929 |
| OSMR | oncostatin M receptor | -0.030167 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0301498 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0300772 |
| PRKCA | protein kinase C, alpha | -0.0297408 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0297334 |
| RRBP1 | ribosome binding protein 1 | -0.0294358 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0293709 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0290552 |
| H3-3B | H3.3 histone B | -0.0289116 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0286767 |
| EFNA5 | ephrin-A5 | -0.0285288 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0283583 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0283551 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0281944 |
| FTL | ferritin, light polypeptide | -0.0279639 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0277097 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0277058 |
| MUC4 | mucin 4, cell surface associated | -0.0275002 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0273266 |
| RBM47 | RNA binding motif protein 47 | -0.0269278 |
| ERBIN | erbb2 interacting protein | -0.0268318 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0265016 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0264913 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0263795 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0263649 |
| IRF1 | interferon regulatory factor 1 | -0.0262688 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0262326 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.025674 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0255182 |
| JUP | junction plakoglobin | -0.025181 |
| B2M | beta-2-microglobulin | -0.0247404 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0243519 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0239973 |
| IL6ST | interleukin 6 signal transducer | -0.0239618 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0239045 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0238334 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0235664 |
| TAPBP | TAP binding protein (tapasin) | -0.0235417 |
