| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.197306 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.123116 |
| FAM13A | family with sequence similarity 13, member A | 0.121673 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.113102 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100947 |
| DST | dystonin | 0.0805924 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0767042 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0738157 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0733279 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0704201 |
| MEF2A | myocyte enhancer factor 2A | 0.0685624 |
| CENPF | centromere protein F, 350/400kDa | 0.0675334 |
| SEPTIN9 | septin 9 | 0.0643418 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0624771 |
| TRIB2 | tribbles pseudokinase 2 | 0.0598303 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0585009 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0568808 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0562707 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.055932 |
| LPIN1 | lipin 1 | 0.0555694 |
| MKI67 | marker of proliferation Ki-67 | 0.0533841 |
| SET | SET nuclear proto-oncogene | 0.0518826 |
| NRG1 | neuregulin 1 | 0.0511437 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0508266 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0503791 |
| SMAD3 | SMAD family member 3 | 0.0500751 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0500555 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0494518 |
| ZNF292 | zinc finger protein 292 | 0.0492161 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0478652 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0474828 |
| PGK1 | phosphoglycerate kinase 1 | 0.0474452 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.046852 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0467023 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.046191 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0446992 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0440004 |
| NDRG1 | N-myc downstream regulated 1 | 0.0437952 |
| ENO1 | enolase 1, (alpha) | 0.0436137 |
| RPL37A | ribosomal protein L37a | 0.0429871 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0423395 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.042338 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.042101 |
| COL3A1 | collagen, type III, alpha 1 | 0.0418852 |
| RNF213 | ring finger protein 213 | 0.0415508 |
| PKM | pyruvate kinase, muscle | 0.0414458 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0408963 |
| RPL4 | ribosomal protein L4 | 0.0403925 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0397304 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0397124 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0395757 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0394259 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0387945 |
| ASPH | aspartate beta-hydroxylase | 0.0384095 |
| RPS12 | ribosomal protein S12 | 0.0379351 |
| RPL3 | ribosomal protein L3 | 0.0370991 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0367738 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0367538 |
| ZNF148 | zinc finger protein 148 | 0.0363739 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0359849 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0354922 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0352982 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0350321 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0350191 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0347833 |
| DTNA | dystrobrevin, alpha | 0.0347731 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0344334 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0338227 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335655 |
| LDHA | lactate dehydrogenase A | 0.0332065 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.033159 |
| HDGF | hepatoma-derived growth factor | 0.0328131 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0327515 |
| ARRDC3 | arrestin domain containing 3 | 0.0327352 |
| RGS4 | regulator of G-protein signaling 4 | 0.0324808 |
| XPO1 | exportin 1 | 0.0317333 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0316223 |
| ATXN1 | ataxin 1 | 0.0310167 |
| CCNY | cyclin Y | 0.0309504 |
| PRKCE | protein kinase C, epsilon | 0.0307331 |
| RAD51B | RAD51 paralog B | 0.0302226 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0299858 |
| KIAA1217 | KIAA1217 | 0.0295795 |
| RPS2 | ribosomal protein S2 | 0.0294157 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0291158 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0290886 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0290055 |
| HELZ | helicase with zinc finger | 0.0288972 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0288948 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0288599 |
| MYO1B | myosin IB | 0.0286234 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0280551 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0278862 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0278467 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0277714 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0275634 |
| ANGPTL4 | angiopoietin-like 4 | 0.0273477 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0270946 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0269654 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0268171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.317734 |
| SYT1 | synaptotagmin I | -0.118381 |
| IGF2 | insulin-like growth factor 2 | -0.0964502 |
| VCL | vinculin | -0.0931299 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0923 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0740277 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.072412 |
| RPLP1 | ribosomal protein, large, P1 | -0.0690082 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0681317 |
| COL1A1 | collagen, type I, alpha 1 | -0.0645132 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0619348 |
| IER3 | immediate early response 3 | -0.0586062 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.057113 |
| VMP1 | vacuole membrane protein 1 | -0.0540962 |
| GLCCI1 | glucocorticoid induced 1 | -0.0527502 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0523251 |
| EGR1 | early growth response 1 | -0.0521458 |
| RPS6 | ribosomal protein S6 | -0.0501494 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0496743 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0492881 |
| BPTF | bromodomain PHD finger transcription factor | -0.049056 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0483534 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0478695 |
| FMN1 | formin 1 | -0.0470635 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0466599 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0455664 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0451837 |
| SIK2 | salt-inducible kinase 2 | -0.043596 |
| TLE4 | transducin-like enhancer of split 4 | -0.0432589 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0414467 |
| TPM1 | tropomyosin 1 (alpha) | -0.0414457 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0412864 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0412588 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0401692 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0392509 |
| MED13 | mediator complex subunit 13 | -0.0380687 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.037976 |
| FTL | ferritin, light polypeptide | -0.0378625 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0377494 |
| H3-3B | H3.3 histone B | -0.0375909 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0375673 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.036951 |
| COL4A5 | collagen, type IV, alpha 5 | -0.035613 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0356036 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0354206 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0352159 |
| LSAMP | limbic system-associated membrane protein | -0.0347346 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0347296 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0333181 |
| H1-0 | H1.0 linker histone | -0.0332523 |
| GOLGA4 | golgin A4 | -0.0323883 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0323183 |
| LRRC7 | leucine rich repeat containing 7 | -0.0317165 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0313572 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0312021 |
| RPS15 | ribosomal protein S15 | -0.0310228 |
| HDLBP | high density lipoprotein binding protein | -0.0302676 |
| PLPP1 | phospholipid phosphatase 1 | -0.0298931 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.029744 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0280644 |
| STK38L | serine/threonine kinase 38 like | -0.0280548 |
| PTMA | prothymosin, alpha | -0.0279479 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0278978 |
| KLHL13 | kelch-like family member 13 | -0.0277438 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0277408 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0276609 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0275695 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0271407 |
| RPL34 | ribosomal protein L34 | -0.0269126 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0267067 |
| GDF15 | growth differentiation factor 15 | -0.026685 |
| RPL19 | ribosomal protein L19 | -0.0266454 |
| CDK12 | cyclin-dependent kinase 12 | -0.0265615 |
| USP36 | ubiquitin specific peptidase 36 | -0.0261878 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0256411 |
| POGZ | pogo transposable element with ZNF domain | -0.0254338 |
| MEIS2 | Meis homeobox 2 | -0.0254066 |
| NUP160 | nucleoporin 160kDa | -0.0253492 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0251593 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0247335 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0247195 |
| MBTD1 | mbt domain containing 1 | -0.0244725 |
| MAP1B | microtubule-associated protein 1B | -0.0243789 |
| TPM4 | tropomyosin 4 | -0.0243316 |
| TBCA | tubulin folding cofactor A | -0.0242993 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0242465 |
| GOLGB1 | golgin B1 | -0.0242257 |
| RPL35A | ribosomal protein L35a | -0.0240758 |
| RSPRY1 | ring finger and SPRY domain containing 1 | -0.0240453 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0238869 |
| ACTG1 | actin gamma 1 | -0.0237726 |
| OGA | O-GlcNAcase | -0.0227033 |
| ZNF609 | zinc finger protein 609 | -0.0226442 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0225183 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0224528 |
| RPS21 | ribosomal protein S21 | -0.0223766 |
| RPL38 | ribosomal protein L38 | -0.0223503 |
| SEC23IP | SEC23 interacting protein | -0.0223042 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0221898 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0221249 |
