| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.160621 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.127988 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.104558 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0792361 |
| FAM13A | family with sequence similarity 13, member A | 0.0788923 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0778386 |
| PGK1 | phosphoglycerate kinase 1 | 0.0760168 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0758103 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.069786 |
| ASPH | aspartate beta-hydroxylase | 0.0689809 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0668112 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0659506 |
| STC1 | stanniocalcin 1 | 0.0578787 |
| SET | SET nuclear proto-oncogene | 0.0574102 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.056995 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0544772 |
| FLNA | filamin A, alpha | 0.0544338 |
| PKM | pyruvate kinase, muscle | 0.0532138 |
| LDHA | lactate dehydrogenase A | 0.052681 |
| RPL37A | ribosomal protein L37a | 0.0516512 |
| PLEC | plectin | 0.049945 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0489282 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0459171 |
| DTNA | dystrobrevin, alpha | 0.0450795 |
| RPS2 | ribosomal protein S2 | 0.0445828 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.044503 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0440601 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0439731 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0432624 |
| PRELID2 | PRELI domain containing 2 | 0.0422429 |
| ATP13A3 | ATPase type 13A3 | 0.0422384 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0416173 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0411091 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0410548 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0403229 |
| RPL4 | ribosomal protein L4 | 0.0397236 |
| MKI67 | marker of proliferation Ki-67 | 0.0391701 |
| SEPTIN7 | septin 7 | 0.0391588 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0391426 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0391268 |
| NDRG1 | N-myc downstream regulated 1 | 0.0390218 |
| RPL3 | ribosomal protein L3 | 0.0387576 |
| CD44 | CD44 molecule (Indian blood group) | 0.0385391 |
| YEATS2 | YEATS domain containing 2 | 0.0384984 |
| ENO1 | enolase 1, (alpha) | 0.0383755 |
| SMAD3 | SMAD family member 3 | 0.0368401 |
| APP | amyloid beta (A4) precursor protein | 0.0367591 |
| RPL23 | ribosomal protein L23 | 0.0362741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0357861 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0349007 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0337187 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0334455 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0330288 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0326427 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0326076 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0304432 |
| RPS12 | ribosomal protein S12 | 0.030353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0299441 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0288499 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0285131 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0283506 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0280863 |
| RAB8B | RAB8B, member RAS oncogene family | 0.028083 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.028072 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0280498 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0276499 |
| RPS17 | ribosomal protein S17 | 0.0276015 |
| MSN | moesin | 0.0275347 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0274079 |
| ZNF292 | zinc finger protein 292 | 0.0271709 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0271424 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0269107 |
| RAI1 | retinoic acid induced 1 | 0.0268653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0267051 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0266577 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0265607 |
| ZNF160 | zinc finger protein 160 | 0.026546 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264261 |
| ZNF841 | zinc finger protein 841 | 0.0264255 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0263825 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0259759 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259703 |
| NUP58 | nucleoporin 58 | 0.0259059 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.025807 |
| NAV2 | neuron navigator 2 | 0.0257855 |
| TPM3 | tropomyosin 3 | 0.0257569 |
| ZNF395 | zinc finger protein 395 | 0.0257432 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0256486 |
| FLNB | filamin B, beta | 0.0253612 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0252679 |
| RPL26 | ribosomal protein L26 | 0.0252447 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0252362 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0251457 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0250654 |
| HMGB2 | high mobility group box 2 | 0.0250353 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0248981 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0244477 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0241928 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0241358 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0240086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.306309 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.305012 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0959928 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0944216 |
| FTL | ferritin, light polypeptide | -0.0890006 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0808369 |
| GDF15 | growth differentiation factor 15 | -0.0666105 |
| EGR1 | early growth response 1 | -0.0658911 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0656346 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0652877 |
| TMSB10 | thymosin beta 10 | -0.0640204 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0637609 |
| GOLGB1 | golgin B1 | -0.0629322 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0626999 |
| SCFD2 | sec1 family domain containing 2 | -0.05965 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0587805 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0576867 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0575483 |
| FN1 | fibronectin 1 | -0.0572134 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0559134 |
| INHBA | inhibin, beta A | -0.0544978 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0519757 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0475883 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0470563 |
| DST | dystonin | -0.0452855 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0438935 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0423536 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0421524 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0420167 |
| VMP1 | vacuole membrane protein 1 | -0.0419503 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0418454 |
| SEC24D | SEC24 family member D | -0.0411815 |
| MAP4 | microtubule-associated protein 4 | -0.040649 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0400619 |
| KYNU | kynureninase | -0.0393893 |
| CLINT1 | clathrin interactor 1 | -0.0392885 |
| PTCHD4 | patched domain containing 4 | -0.0387067 |
| NOP58 | NOP58 ribonucleoprotein | -0.0385674 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0381709 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0364561 |
| CADM1 | cell adhesion molecule 1 | -0.0363898 |
| ARF4 | ADP-ribosylation factor 4 | -0.0362049 |
| GPR173 | G protein-coupled receptor 173 | -0.0344353 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0341062 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0338438 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0337576 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0337457 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0336932 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0336345 |
| UBAP2 | ubiquitin associated protein 2 | -0.0331166 |
| GOLGA4 | golgin A4 | -0.0327506 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0327138 |
| CDK13 | cyclin-dependent kinase 13 | -0.0327046 |
| LOX | lysyl oxidase | -0.0324452 |
| TNNC1 | troponin C type 1 (slow) | -0.0323445 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0322811 |
| SUCO | SUN domain containing ossification factor | -0.0314415 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0314013 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0311879 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0309723 |
| ATM | ATM serine/threonine kinase | -0.0308959 |
| SBF2 | SET binding factor 2 | -0.0308272 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0307368 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0306731 |
| NBEAL1 | neurobeachin-like 1 | -0.0304934 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0304357 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0303306 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0299266 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0286852 |
| VEGFA | vascular endothelial growth factor A | -0.0283221 |
| USP36 | ubiquitin specific peptidase 36 | -0.0282695 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0278571 |
| TMEM263 | transmembrane protein 263 | -0.0278373 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.027792 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0275649 |
| SCFD1 | sec1 family domain containing 1 | -0.0272501 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0270935 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.026817 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0267833 |
| MAP1B | microtubule-associated protein 1B | -0.0265914 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0264492 |
| HDLBP | high density lipoprotein binding protein | -0.0263397 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0261367 |
| CANX | calnexin | -0.0260438 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0259676 |
| NABP1 | nucleic acid binding protein 1 | -0.0258249 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0257964 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0257504 |
| AAK1 | AP2 associated kinase 1 | -0.0257073 |
| PHF14 | PHD finger protein 14 | -0.0253091 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0252471 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0251821 |
| COG5 | component of oligomeric golgi complex 5 | -0.0249164 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0243429 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0241981 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0241451 |
| FNIP1 | folliculin interacting protein 1 | -0.0240684 |
| GNAS | GNAS complex locus | -0.0239875 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.023972 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0235951 |
