| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.167098 |
| PRELID2 | PRELI domain containing 2 | 0.103019 |
| PGK1 | phosphoglycerate kinase 1 | 0.0898627 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0858783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0837297 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0819952 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0800549 |
| RPL35A | ribosomal protein L35a | 0.0720782 |
| ZNF292 | zinc finger protein 292 | 0.0661326 |
| MT2A | metallothionein 2A | 0.0653601 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0637442 |
| TBC1D22A | TBC1 domain family, member 22A | 0.062172 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0569795 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0526444 |
| FAM117B | family with sequence similarity 117, member B | 0.0496839 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0483457 |
| RAD51B | RAD51 paralog B | 0.0443573 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0441235 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0437075 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0433731 |
| KIAA1217 | KIAA1217 | 0.0429496 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0404749 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0390457 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0375626 |
| RPL4 | ribosomal protein L4 | 0.0359808 |
| FTL | ferritin, light polypeptide | 0.0354082 |
| FAM162A | family with sequence similarity 162, member A | 0.0351848 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0340732 |
| TPR | translocated promoter region, nuclear basket protein | 0.0340312 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0331928 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0329126 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0326309 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0326115 |
| HPCAL1 | hippocalcin-like 1 | 0.0317895 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.031747 |
| RPL23 | ribosomal protein L23 | 0.0314492 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0313256 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0311843 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0306414 |
| NUP58 | nucleoporin 58 | 0.0305474 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0304372 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0302162 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0296305 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0290202 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0281042 |
| TMSB10 | thymosin beta 10 | 0.0278479 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0278361 |
| CALR | calreticulin | 0.0272787 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0262337 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0261356 |
| GANAB | glucosidase, alpha; neutral AB | 0.0259673 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0253986 |
| TMEM41B | transmembrane protein 41B | 0.0249792 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0248047 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.024762 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0247464 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0246908 |
| MKI67 | marker of proliferation Ki-67 | 0.0246788 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0245751 |
| FANCI | Fanconi anemia, complementation group I | 0.0245453 |
| SERTAD2 | SERTA domain containing 2 | 0.0243845 |
| UBXN7 | UBX domain protein 7 | 0.0240619 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0238445 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0236897 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0234727 |
| NEBL | nebulette | 0.0234401 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0233523 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0231231 |
| RIOK3 | RIO kinase 3 | 0.0227995 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0225081 |
| WDR45B | WD repeat domain 45B | 0.0224026 |
| ASPH | aspartate beta-hydroxylase | 0.0222082 |
| VIM | vimentin | 0.0222078 |
| GPATCH2L | G patch domain containing 2-like | 0.0220975 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0217829 |
| ZNF511 | zinc finger protein 511 | 0.021556 |
| KAZN | kazrin, periplakin interacting protein | 0.0213789 |
| HOXB3 | homeobox B3 | 0.0212459 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0212404 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0210367 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0209675 |
| RPS29 | ribosomal protein S29 | 0.0209549 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0209376 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0209354 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0205655 |
| ANGPTL4 | angiopoietin-like 4 | 0.0205459 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.0204997 |
| ATL2 | atlastin GTPase 2 | 0.0204364 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 | 0.0203644 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0203582 |
| INTS13 | integrator complex subunit 13 | 0.0201495 |
| MLEC | malectin | 0.0200412 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0199864 |
| ATXN2L | ataxin 2-like | 0.0199439 |
| RRM2 | ribonucleotide reductase M2 | 0.0198554 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0197878 |
| RPL37A | ribosomal protein L37a | 0.0197602 |
| LASP1 | LIM and SH3 protein 1 | 0.0196542 |
| INSIG2 | insulin induced gene 2 | 0.0195856 |
| RPL26 | ribosomal protein L26 | 0.0193709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.315061 |
| AHNAK | AHNAK nucleoprotein | -0.147202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.126044 |
| RPS6 | ribosomal protein S6 | -0.0958321 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.088357 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0757253 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0686758 |
| FAT1 | FAT atypical cadherin 1 | -0.0662163 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0634047 |
| RPS2 | ribosomal protein S2 | -0.0589241 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0582251 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0567208 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0518138 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0512771 |
| RBM39 | RNA binding motif protein 39 | -0.0498227 |
| POTEF | POTE ankyrin domain family, member F | -0.049744 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0494344 |
| PTMA | prothymosin, alpha | -0.0493637 |
| EZR | ezrin | -0.0493431 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0487358 |
| GPHN | gephyrin | -0.0485809 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0461929 |
| HDLBP | high density lipoprotein binding protein | -0.0458302 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0450649 |
| CUX1 | cut-like homeobox 1 | -0.0450234 |
| PCBP2 | poly(rC) binding protein 2 | -0.044979 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0448899 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0448818 |
| PKM | pyruvate kinase, muscle | -0.0448401 |
| VCL | vinculin | -0.0441765 |
| ENO1 | enolase 1, (alpha) | -0.043374 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0424585 |
| EGR1 | early growth response 1 | -0.042423 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0416363 |
| TENM3 | teneurin transmembrane protein 3 | -0.0393581 |
| FRMD5 | FERM domain containing 5 | -0.0384694 |
| INTS6 | integrator complex subunit 6 | -0.0383896 |
| USP34 | ubiquitin specific peptidase 34 | -0.0377705 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0377188 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.037097 |
| TAOK1 | TAO kinase 1 | -0.0370716 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0367344 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0365661 |
| BRD2 | bromodomain containing 2 | -0.03639 |
| RHOA | ras homolog family member A | -0.0362219 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0361976 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0357969 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0354901 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0351039 |
| MCL1 | myeloid cell leukemia 1 | -0.0350143 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0350066 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0349418 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0343449 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0343278 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0339536 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0336402 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0335495 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0334511 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0334294 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0332605 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0332143 |
| CADPS | Ca++-dependent secretion activator | -0.0331427 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0330591 |
| GOLGA4 | golgin A4 | -0.0329124 |
| IPO7 | importin 7 | -0.0326074 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0325322 |
| JMJD1C | jumonji domain containing 1C | -0.0322518 |
| DIAPH1 | diaphanous-related formin 1 | -0.0317375 |
| NF1 | neurofibromin 1 | -0.0316512 |
| NKTR | natural killer cell triggering receptor | -0.0315214 |
| RBMX | RNA binding motif protein, X-linked | -0.0313229 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.031203 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0311935 |
| CANX | calnexin | -0.0311385 |
| TJP1 | tight junction protein 1 | -0.0310081 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0308203 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0307753 |
| MSI2 | musashi RNA-binding protein 2 | -0.0303688 |
| MED13 | mediator complex subunit 13 | -0.0302563 |
| CMIP | c-Maf inducing protein | -0.0300744 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0300512 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0299706 |
| FUS | FUS RNA binding protein | -0.0296786 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0292634 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0291307 |
| RBM6 | RNA binding motif protein 6 | -0.0289725 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0289248 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.028876 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0288304 |
| VEGFA | vascular endothelial growth factor A | -0.0287046 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0286242 |
| WWC2 | WW and C2 domain containing 2 | -0.0285549 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0284146 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0282065 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.028138 |
| RAB10 | RAB10, member RAS oncogene family | -0.0277558 |
| MORF4L2 | mortality factor 4 like 2 | -0.0277411 |
| PKP4 | plakophilin 4 | -0.0275484 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0274519 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0272844 |
