| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.103843 |
| FLNA | filamin A, alpha | 0.0650865 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0392882 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0379281 |
| SET | SET nuclear proto-oncogene | 0.0359388 |
| PLEC | plectin | 0.0331128 |
| PRELID2 | PRELI domain containing 2 | 0.0283843 |
| AFDN | afadin, adherens junction formation factor | 0.0245505 |
| RPS12 | ribosomal protein S12 | 0.0241486 |
| RPL3 | ribosomal protein L3 | 0.0231771 |
| NCKAP1 | NCK-associated protein 1 | 0.0219849 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213204 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212793 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0198821 |
| NUP58 | nucleoporin 58 | 0.0198586 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0194299 |
| RASA2 | RAS p21 protein activator 2 | 0.0184779 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0183884 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0182727 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0182532 |
| RPS2 | ribosomal protein S2 | 0.0175316 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0174717 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.017152 |
| ATP13A3 | ATPase type 13A3 | 0.0168642 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0162023 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.016015 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0154735 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.014931 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0146917 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0146036 |
| PFN1 | profilin 1 | 0.0144225 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0141672 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0139956 |
| BARD1 | BRCA1 associated RING domain 1 | 0.0138867 |
| MYEF2 | myelin expression factor 2 | 0.0135622 |
| RPL37A | ribosomal protein L37a | 0.0135454 |
| UBQLN1 | ubiquilin 1 | 0.0134493 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0131645 |
| CLDN4 | claudin 4 | 0.0130821 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0130743 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.012981 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0124941 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0124892 |
| WDR43 | WD repeat domain 43 | 0.0124065 |
| ANXA3 | annexin A3 | 0.0123683 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0122393 |
| RPSA | ribosomal protein SA | 0.0122353 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0122154 |
| PNN | pinin, desmosome associated protein | 0.0120563 |
| RPL13A | ribosomal protein L13a | 0.0117205 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0113775 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0113211 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0111479 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.0110559 |
| HDGF | hepatoma-derived growth factor | 0.0110269 |
| CCDC93 | coiled-coil domain containing 93 | 0.0110203 |
| RPS17 | ribosomal protein S17 | 0.0109432 |
| RPL18 | ribosomal protein L18 | 0.0108555 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0108274 |
| DENND5A | DENN/MADD domain containing 5A | 0.0107652 |
| MAMLD1 | mastermind-like domain containing 1 | 0.0107072 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0105378 |
| SMAD5 | SMAD family member 5 | 0.0104034 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0102246 |
| RNF145 | ring finger protein 145 | 0.010148 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.00995682 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.00994424 |
| ACTN1 | actinin, alpha 1 | 0.00992974 |
| ANKRD36B | ankyrin repeat domain 36B | 0.00988849 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00986363 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00977547 |
| WRN | Werner syndrome, RecQ helicase-like | 0.00946607 |
| GPX4 | glutathione peroxidase 4 | 0.00940121 |
| MEAK7 | MTOR associated protein, eak-7 homolog | 0.00932204 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00928323 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0091608 |
| TIMM23B | translocase of inner mitochondrial membrane 23 homolog B (yeast) | 0.00914681 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.00908185 |
| SERINC1 | serine incorporator 1 | 0.00897631 |
| CUL3 | cullin 3 | 0.00895328 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.00890011 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00883178 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.0087676 |
| AXL | AXL receptor tyrosine kinase | 0.00874437 |
| SLTM | SAFB-like, transcription modulator | 0.00867507 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.00867024 |
| MYEOV | myeloma overexpressed | 0.00866003 |
| RANBP2 | RAN binding protein 2 | 0.00857038 |
| RPL29 | ribosomal protein L29 | 0.00855243 |
| ANKRD36C | ankyrin repeat domain 36C | 0.00843773 |
| RPS3 | ribosomal protein S3 | 0.00843711 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0084221 |
| PLPP6 | phospholipid phosphatase 6 | 0.00839428 |
| VRK1 | vaccinia related kinase 1 | 0.00839101 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00837972 |
| PCBP1 | poly(rC) binding protein 1 | 0.00837828 |
| PRPF39 | pre-mRNA processing factor 39 | 0.00829671 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00828067 |
| HMGXB3 | HMG box domain containing 3 | 0.0082418 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00823569 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.366853 |
| AHNAK | AHNAK nucleoprotein | -0.126976 |
| ASPH | aspartate beta-hydroxylase | -0.105417 |
| ACTG1 | actin gamma 1 | -0.104539 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102048 |
| CCND1 | cyclin D1 | -0.0912327 |
| RPS6 | ribosomal protein S6 | -0.0890137 |
| ANXA2 | annexin A2 | -0.0858005 |
| ENO1 | enolase 1, (alpha) | -0.082112 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0816476 |
| TPM4 | tropomyosin 4 | -0.0813684 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0711982 |
| LDHA | lactate dehydrogenase A | -0.0653401 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0649992 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0646256 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0639098 |
| CANX | calnexin | -0.0636892 |
| DSG2 | desmoglein 2 | -0.0635343 |
| S100A10 | S100 calcium binding protein A10 | -0.0625663 |
| NDRG1 | N-myc downstream regulated 1 | -0.0604216 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0596589 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0584219 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0581273 |
| PTMA | prothymosin, alpha | -0.0579103 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0548423 |
| MAP4 | microtubule-associated protein 4 | -0.053967 |
| FTL | ferritin, light polypeptide | -0.0518944 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0513497 |
| GOLGB1 | golgin B1 | -0.0480478 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.047959 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0479505 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0476601 |
| SQSTM1 | sequestosome 1 | -0.0470054 |
| TXNRD1 | thioredoxin reductase 1 | -0.0466857 |
| CD2AP | CD2-associated protein | -0.0465404 |
| BPTF | bromodomain PHD finger transcription factor | -0.046106 |
| PKM | pyruvate kinase, muscle | -0.0453093 |
| LAMB3 | laminin, beta 3 | -0.0447272 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0429203 |
| H1-0 | H1.0 linker histone | -0.0428144 |
| KRT7 | keratin 7, type II | -0.041491 |
| TAOK1 | TAO kinase 1 | -0.0408822 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0405002 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0400097 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0394823 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0393753 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0392808 |
| SSH2 | slingshot protein phosphatase 2 | -0.0391722 |
| SVIL | supervillin | -0.0391142 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0385315 |
| CD44 | CD44 molecule (Indian blood group) | -0.0380734 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0377499 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0377173 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0374712 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0372955 |
| MKI67 | marker of proliferation Ki-67 | -0.0371573 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0359846 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0359722 |
| RPLP0 | ribosomal protein, large, P0 | -0.0358978 |
| BBX | bobby sox homolog (Drosophila) | -0.0355586 |
| RAD51B | RAD51 paralog B | -0.0353945 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0351564 |
| RPL12 | ribosomal protein L12 | -0.0349341 |
| EGR1 | early growth response 1 | -0.0349315 |
| RPL32 | ribosomal protein L32 | -0.0346175 |
| RUNX1 | runt-related transcription factor 1 | -0.0345929 |
| PTK2 | protein tyrosine kinase 2 | -0.0345704 |
| HDLBP | high density lipoprotein binding protein | -0.0344757 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0344044 |
| IER3 | immediate early response 3 | -0.0340727 |
| LAMA4 | laminin, alpha 4 | -0.0328094 |
| HMGB1 | high mobility group box 1 | -0.0325962 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0325831 |
| SETD5 | SET domain containing 5 | -0.0325108 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0324592 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0321482 |
| HMGA2 | high mobility group AT-hook 2 | -0.0321335 |
| UBC | ubiquitin C | -0.0321073 |
| NF1 | neurofibromin 1 | -0.0317425 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0312966 |
| RPL34 | ribosomal protein L34 | -0.0312466 |
| DSTN | destrin (actin depolymerizing factor) | -0.031209 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0311836 |
| RPLP1 | ribosomal protein, large, P1 | -0.0311746 |
| DEK | DEK proto-oncogene | -0.0310252 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.031014 |
| S100A9 | S100 calcium binding protein A9 | -0.0307264 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0305194 |
| TUBA1B | tubulin, alpha 1b | -0.0303844 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0301445 |
| H3-3B | H3.3 histone B | -0.0299105 |
| PGK1 | phosphoglycerate kinase 1 | -0.029885 |
| S100A6 | S100 calcium binding protein A6 | -0.029837 |
| POTEF | POTE ankyrin domain family, member F | -0.0296174 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0294693 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0292161 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0290282 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0289078 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0288258 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0285805 |
