| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.281191 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.171517 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.125822 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.113612 |
| ATP13A3 | ATPase type 13A3 | 0.0973279 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.090631 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0845506 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0821817 |
| PLEC | plectin | 0.0746308 |
| STC1 | stanniocalcin 1 | 0.0736508 |
| CD44 | CD44 molecule (Indian blood group) | 0.0724178 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0701203 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0696438 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0668989 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0627456 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.062249 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0611607 |
| NAV2 | neuron navigator 2 | 0.0609829 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0593181 |
| VIM | vimentin | 0.0584437 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.05735 |
| CADM1 | cell adhesion molecule 1 | 0.0544982 |
| ARRDC3 | arrestin domain containing 3 | 0.0524378 |
| CALR | calreticulin | 0.0524227 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.051913 |
| LOXL2 | lysyl oxidase-like 2 | 0.0515401 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0510241 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0485988 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0467205 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0459151 |
| SPAG9 | sperm associated antigen 9 | 0.0452909 |
| APP | amyloid beta (A4) precursor protein | 0.0451245 |
| FN1 | fibronectin 1 | 0.0445395 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0441296 |
| MTSS1 | metastasis suppressor 1 | 0.0422747 |
| LDHA | lactate dehydrogenase A | 0.040396 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0396802 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.03947 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0387594 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.038539 |
| RPL3 | ribosomal protein L3 | 0.0382418 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0376393 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0376173 |
| PRELID2 | PRELI domain containing 2 | 0.0375268 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0370724 |
| ENO1 | enolase 1, (alpha) | 0.0370401 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0369655 |
| TMSB4X | thymosin beta 4, X-linked | 0.0369199 |
| HYOU1 | hypoxia up-regulated 1 | 0.0363473 |
| PGK1 | phosphoglycerate kinase 1 | 0.0359096 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0355153 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0334947 |
| H1-4 | H1.4 linker histone, cluster member | 0.03318 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0324413 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0321628 |
| SMAD3 | SMAD family member 3 | 0.031533 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0309659 |
| PTK2 | protein tyrosine kinase 2 | 0.0297503 |
| YEATS2 | YEATS domain containing 2 | 0.0295391 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0294847 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0286453 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0281738 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0281 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0278115 |
| CENPF | centromere protein F, 350/400kDa | 0.0277966 |
| FMNL2 | formin-like 2 | 0.0275213 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0274145 |
| ASPH | aspartate beta-hydroxylase | 0.0261999 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0256719 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0254825 |
| TPR | translocated promoter region, nuclear basket protein | 0.0253993 |
| ANGPTL4 | angiopoietin-like 4 | 0.0250493 |
| MRTFA | myocardin related transcription factor A | 0.0249698 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0248357 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0245004 |
| SQLE | squalene epoxidase | 0.0239714 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0238158 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0236609 |
| RPS12 | ribosomal protein S12 | 0.023652 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.023564 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.023399 |
| CANX | calnexin | 0.0233727 |
| TMF1 | TATA element modulatory factor 1 | 0.0232728 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0232475 |
| ADM | adrenomedullin | 0.0231629 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0230632 |
| RASA2 | RAS p21 protein activator 2 | 0.0230503 |
| COG5 | component of oligomeric golgi complex 5 | 0.0227556 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0225836 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0225817 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223851 |
| MSN | moesin | 0.0222483 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0222402 |
| RPL4 | ribosomal protein L4 | 0.0221016 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.022007 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0217211 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0217203 |
| RARB | retinoic acid receptor, beta | 0.0216213 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0215713 |
| ANXA5 | annexin A5 | 0.0215418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.339442 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.238616 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.170755 |
| COL1A1 | collagen, type I, alpha 1 | -0.128973 |
| MT2A | metallothionein 2A | -0.0905194 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0788067 |
| TMSB10 | thymosin beta 10 | -0.0774492 |
| FTL | ferritin, light polypeptide | -0.0553156 |
| FBN1 | fibrillin 1 | -0.0534732 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.051372 |
| HMGA2 | high mobility group AT-hook 2 | -0.0508244 |
| MT1X | metallothionein 1X | -0.0501413 |
| GLIS3 | GLIS family zinc finger 3 | -0.0496591 |
| CDH13 | cadherin 13 | -0.0464353 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0418261 |
| IER3 | immediate early response 3 | -0.0404085 |
| RPL28 | ribosomal protein L28 | -0.037566 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0374249 |
| RPL35A | ribosomal protein L35a | -0.036967 |
| S100A9 | S100 calcium binding protein A9 | -0.0366747 |
| ACTG1 | actin gamma 1 | -0.0364678 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0350942 |
| POTEF | POTE ankyrin domain family, member F | -0.032518 |
| TAPBP | TAP binding protein (tapasin) | -0.0324396 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0319542 |
| COL1A2 | collagen, type I, alpha 2 | -0.0304383 |
| CALD1 | caldesmon 1 | -0.0299646 |
| RPS6 | ribosomal protein S6 | -0.0289214 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0277968 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0269578 |
| RPLP1 | ribosomal protein, large, P1 | -0.0269067 |
| RPS19 | ribosomal protein S19 | -0.0260699 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0255964 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.025198 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025168 |
| RPL8 | ribosomal protein L8 | -0.0247947 |
| EGR1 | early growth response 1 | -0.0247357 |
| NEK10 | NIMA-related kinase 10 | -0.0246633 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0243434 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0241532 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0241104 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0237344 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0228448 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0227833 |
| PALLD | palladin, cytoskeletal associated protein | -0.0227214 |
| RPL32 | ribosomal protein L32 | -0.0223657 |
| UBC | ubiquitin C | -0.0223435 |
| RPLP2 | ribosomal protein, large, P2 | -0.022279 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0214744 |
| VEGFA | vascular endothelial growth factor A | -0.0210305 |
| RPLP0 | ribosomal protein, large, P0 | -0.0209621 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0206898 |
| RPS21 | ribosomal protein S21 | -0.0205066 |
| RPS15 | ribosomal protein S15 | -0.020401 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0202868 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.020269 |
| H1-0 | H1.0 linker histone | -0.0200848 |
| NABP1 | nucleic acid binding protein 1 | -0.0200158 |
| TMEM263 | transmembrane protein 263 | -0.0198633 |
| PFN1 | profilin 1 | -0.0197889 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.019576 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0194651 |
| RPS5 | ribosomal protein S5 | -0.0190441 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0188467 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0188432 |
| CNTN5 | contactin 5 | -0.0187434 |
| RPL12 | ribosomal protein L12 | -0.0184588 |
| INTS6 | integrator complex subunit 6 | -0.0183316 |
| PXDN | peroxidasin | -0.0182509 |
| TPM1 | tropomyosin 1 (alpha) | -0.0177513 |
| TBCA | tubulin folding cofactor A | -0.0177387 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0177286 |
| RPS16 | ribosomal protein S16 | -0.0174646 |
| THY1 | Thy-1 cell surface antigen | -0.0173821 |
| BSG | basigin (Ok blood group) | -0.0172827 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.017134 |
| RPS14 | ribosomal protein S14 | -0.0170717 |
| ARF4 | ADP-ribosylation factor 4 | -0.0170294 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0170058 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0169796 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0169584 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0169344 |
| HDLBP | high density lipoprotein binding protein | -0.0168767 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0168303 |
| SHISA5 | shisa family member 5 | -0.0166031 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0164345 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0163687 |
| RASAL2 | RAS protein activator like 2 | -0.0161732 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0161682 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0161498 |
| RPS23 | ribosomal protein S23 | -0.0160908 |
| WASF2 | WAS protein family, member 2 | -0.0159061 |
| DGKI | diacylglycerol kinase, iota | -0.0156509 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0155567 |
| EHD2 | EH-domain containing 2 | -0.0155315 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0154682 |
| FUS | FUS RNA binding protein | -0.015449 |
| HMCN1 | hemicentin 1 | -0.0153802 |
| RPS24 | ribosomal protein S24 | -0.0151464 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0151212 |
