| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RAD21 | RAD21 homolog (S. pombe) | 0.0926048 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.063541 |
| PGK1 | phosphoglycerate kinase 1 | 0.063161 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0617305 |
| PRELID2 | PRELI domain containing 2 | 0.0606392 |
| FAM13A | family with sequence similarity 13, member A | 0.0570844 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0520262 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0512173 |
| RPL4 | ribosomal protein L4 | 0.0511097 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0486809 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0483213 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0482396 |
| MKI67 | marker of proliferation Ki-67 | 0.0476509 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0464786 |
| HMGB2 | high mobility group box 2 | 0.0442036 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0436714 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0435033 |
| ZNF292 | zinc finger protein 292 | 0.0432602 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0424092 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0415055 |
| RPS12 | ribosomal protein S12 | 0.0407201 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0402858 |
| KRT8 | keratin 8, type II | 0.0402622 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.04006 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0383169 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0376648 |
| RPL23 | ribosomal protein L23 | 0.0375912 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0374882 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0365919 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.036443 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0362446 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0357086 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0351894 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348998 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0345737 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0338894 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0337794 |
| NFIA | nuclear factor I/A | 0.033258 |
| HOXB6 | homeobox B6 | 0.0330528 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0326868 |
| KIF5B | kinesin family member 5B | 0.0324966 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0323275 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0320225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0318173 |
| CENPF | centromere protein F, 350/400kDa | 0.0315806 |
| LAMB3 | laminin, beta 3 | 0.0311226 |
| PDS5B | PDS5 cohesin associated factor B | 0.0310691 |
| NUP58 | nucleoporin 58 | 0.0309581 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0302158 |
| NCKAP1 | NCK-associated protein 1 | 0.0298536 |
| CALR | calreticulin | 0.0298001 |
| SET | SET nuclear proto-oncogene | 0.0297993 |
| HELZ | helicase with zinc finger | 0.029568 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0293227 |
| EPCAM | epithelial cell adhesion molecule | 0.0292025 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0289435 |
| SEPTIN2 | septin 2 | 0.0288001 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0283983 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0283834 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0283805 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0281958 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.027992 |
| RPL37A | ribosomal protein L37a | 0.0275896 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0270896 |
| TPR | translocated promoter region, nuclear basket protein | 0.0265369 |
| RPN1 | ribophorin I | 0.0265077 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0264496 |
| YBX1 | Y box binding protein 1 | 0.0264412 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.026362 |
| HOXB3 | homeobox B3 | 0.0262904 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0258315 |
| AFTPH | aftiphilin | 0.0256097 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.02544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0252547 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0251649 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0251491 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0250074 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0248934 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0248613 |
| NPTN | neuroplastin | 0.0246842 |
| EREG | epiregulin | 0.0246535 |
| CENPE | centromere protein E, 312kDa | 0.0243855 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0243333 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0242743 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0242118 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0241193 |
| HDGF | hepatoma-derived growth factor | 0.0241177 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0241036 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0240395 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0238036 |
| PLEC | plectin | 0.0236591 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0235789 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0233756 |
| LNX2 | ligand of numb-protein X 2 | 0.0231464 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.0231121 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0229613 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0228803 |
| GNAS | GNAS complex locus | 0.0228506 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.0225821 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0225184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147755 |
| TXNRD1 | thioredoxin reductase 1 | -0.138613 |
| FTL | ferritin, light polypeptide | -0.132715 |
| RPS6 | ribosomal protein S6 | -0.128074 |
| TJP1 | tight junction protein 1 | -0.111738 |
| NDRG1 | N-myc downstream regulated 1 | -0.10061 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.091818 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0700475 |
| LMO7 | LIM domain 7 | -0.0675462 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0666534 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0650931 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0640921 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0639435 |
| EGR1 | early growth response 1 | -0.0616258 |
| RPL21 | ribosomal protein L21 | -0.0609465 |
| GOLGB1 | golgin B1 | -0.0596137 |
| UBC | ubiquitin C | -0.0583892 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0578298 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0576517 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0575934 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0564138 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0547476 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0546763 |
| MYO1E | myosin IE | -0.0536465 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0531175 |
| EXT1 | exostosin glycosyltransferase 1 | -0.052737 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0526003 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0524886 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.052012 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0513349 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0504712 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0476078 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0467348 |
| CD2AP | CD2-associated protein | -0.045895 |
| HM13 | histocompatibility (minor) 13 | -0.0457933 |
| BCL2L1 | BCL2-like 1 | -0.0455518 |
| EZR | ezrin | -0.0452593 |
| KRT20 | keratin 20, type I | -0.0448401 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0441101 |
| POTEF | POTE ankyrin domain family, member F | -0.0434518 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0430865 |
| RND3 | Rho family GTPase 3 | -0.0420171 |
| RPS13 | ribosomal protein S13 | -0.0418577 |
| VMP1 | vacuole membrane protein 1 | -0.0414644 |
| RPS5 | ribosomal protein S5 | -0.0412546 |
| SMAD3 | SMAD family member 3 | -0.0411221 |
| WASF2 | WAS protein family, member 2 | -0.0406842 |
| RHEB | Ras homolog enriched in brain | -0.0403481 |
| RTN3 | reticulon 3 | -0.0402494 |
| TMC5 | transmembrane channel-like 5 | -0.0402292 |
| IRF1 | interferon regulatory factor 1 | -0.0400396 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0395958 |
| RPS11 | ribosomal protein S11 | -0.0393651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0372143 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0370779 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0365094 |
| ASTN2 | astrotactin 2 | -0.0363449 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0362844 |
| EXPH5 | exophilin 5 | -0.0360903 |
| RAB10 | RAB10, member RAS oncogene family | -0.035899 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0355357 |
| CANX | calnexin | -0.0349099 |
| RPS16 | ribosomal protein S16 | -0.0343533 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0336074 |
| NTN4 | netrin 4 | -0.0335678 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.032665 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0322349 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.032096 |
| RRBP1 | ribosome binding protein 1 | -0.031932 |
| DSTN | destrin (actin depolymerizing factor) | -0.0319268 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0318689 |
| AHNAK | AHNAK nucleoprotein | -0.0318192 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0317039 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0317006 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0315957 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0311121 |
| RPL28 | ribosomal protein L28 | -0.0310317 |
| ZFP36 | ZFP36 ring finger protein | -0.030898 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -0.0305823 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0305055 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0305009 |
| RPS25 | ribosomal protein S25 | -0.0302575 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0297484 |
| RPLP0 | ribosomal protein, large, P0 | -0.029673 |
| TRIB1 | tribbles pseudokinase 1 | -0.0296707 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0296597 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.029234 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0290833 |
| TRAM1 | translocation associated membrane protein 1 | -0.0289884 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0287766 |
| MAGT1 | magnesium transporter 1 | -0.0285442 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0283833 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0282702 |
| CTBP2 | C-terminal binding protein 2 | -0.0277378 |
| SGMS2 | sphingomyelin synthase 2 | -0.0276245 |
| WWC1 | WW and C2 domain containing 1 | -0.0276239 |
| CCNI | cyclin I | -0.0274055 |
| CLINT1 | clathrin interactor 1 | -0.0270525 |
| ANXA11 | annexin A11 | -0.0270472 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0269299 |
