| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.170664 |
| MEF2A | myocyte enhancer factor 2A | 0.167945 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.144327 |
| MYOF | myoferlin | 0.134227 |
| PGK1 | phosphoglycerate kinase 1 | 0.113972 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.110702 |
| PLEC | plectin | 0.105103 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0807113 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.080681 |
| ENO1 | enolase 1, (alpha) | 0.080322 |
| TMSB4X | thymosin beta 4, X-linked | 0.0795828 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0715894 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0714486 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0703382 |
| KRT17 | keratin 17, type I | 0.0681616 |
| CUL4B | cullin 4B | 0.0678766 |
| ANLN | anillin, actin binding protein | 0.067751 |
| ITGA6 | integrin, alpha 6 | 0.0666357 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0622957 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0615608 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0589626 |
| KIAA1217 | KIAA1217 | 0.0585501 |
| OGA | O-GlcNAcase | 0.0567546 |
| ZNF292 | zinc finger protein 292 | 0.0560866 |
| PRELID2 | PRELI domain containing 2 | 0.0539411 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0538693 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0535091 |
| ASPH | aspartate beta-hydroxylase | 0.0524063 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0511041 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0503064 |
| AHNAK | AHNAK nucleoprotein | 0.0502915 |
| ARRDC3 | arrestin domain containing 3 | 0.0501971 |
| LMNA | lamin A/C | 0.0496797 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0484279 |
| MXI1 | MAX interactor 1, dimerization protein | 0.048362 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0482245 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0481243 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0479086 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0473303 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0472907 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0472655 |
| ANGPTL4 | angiopoietin-like 4 | 0.0463438 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0459876 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0456981 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0453878 |
| CANX | calnexin | 0.0449624 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0447893 |
| KRT6A | keratin 6A, type II | 0.0436104 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0418556 |
| EZR | ezrin | 0.0410466 |
| XPO1 | exportin 1 | 0.04096 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0409597 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0408632 |
| FAM13A | family with sequence similarity 13, member A | 0.0408233 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0407197 |
| CLU | clusterin | 0.0405671 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0404878 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0402449 |
| PKM | pyruvate kinase, muscle | 0.0391541 |
| HELZ | helicase with zinc finger | 0.038993 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0385468 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0376928 |
| TPM3 | tropomyosin 3 | 0.0364656 |
| H1-0 | H1.0 linker histone | 0.035844 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0356745 |
| SPAG9 | sperm associated antigen 9 | 0.0354116 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0352693 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0352639 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0351644 |
| AFAP1 | actin filament associated protein 1 | 0.0347715 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0346657 |
| NUP58 | nucleoporin 58 | 0.0345604 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0344796 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.034393 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0340025 |
| SLK | STE20-like kinase | 0.0339806 |
| SMAD3 | SMAD family member 3 | 0.0339438 |
| GOLGA4 | golgin A4 | 0.0339106 |
| RNF145 | ring finger protein 145 | 0.0338467 |
| PHF21A | PHD finger protein 21A | 0.033792 |
| ANXA2 | annexin A2 | 0.0335703 |
| ANXA1 | annexin A1 | 0.0333221 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0331826 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0329727 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0327345 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0325352 |
| GATA6 | GATA binding protein 6 | 0.032528 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0324107 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0323023 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0322534 |
| PTMA | prothymosin, alpha | 0.032228 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.032006 |
| RPL3 | ribosomal protein L3 | 0.0319526 |
| LDHA | lactate dehydrogenase A | 0.0319427 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0319265 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318182 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0316472 |
| RLF | rearranged L-myc fusion | 0.0313485 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0313338 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0311743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.21048 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.109904 |
| PDLIM5 | PDZ and LIM domain 5 | -0.101123 |
| INTS6 | integrator complex subunit 6 | -0.084144 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0667636 |
| HM13 | histocompatibility (minor) 13 | -0.0648434 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.061632 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0587946 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0574829 |
| IGF2 | insulin-like growth factor 2 | -0.0516214 |
| POTEF | POTE ankyrin domain family, member F | -0.0505279 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0493723 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0465753 |
| EGR1 | early growth response 1 | -0.0464647 |
| RASAL2 | RAS protein activator like 2 | -0.0434088 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0423014 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0395073 |
| LMO7 | LIM domain 7 | -0.0386457 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0382183 |
| HLA-B | major histocompatibility complex, class I, B | -0.0380981 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0377978 |
| EFNA5 | ephrin-A5 | -0.0377932 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0377015 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0370132 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0362598 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.035581 |
| LAMA5 | laminin, alpha 5 | -0.0351523 |
| PALLD | palladin, cytoskeletal associated protein | -0.0351216 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0350817 |
| DGKH | diacylglycerol kinase, eta | -0.0334739 |
| SETX | senataxin | -0.0332512 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0328796 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0328088 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0323229 |
| OSMR | oncostatin M receptor | -0.0321325 |
| CMIP | c-Maf inducing protein | -0.0320288 |
| CDK6 | cyclin-dependent kinase 6 | -0.0315818 |
| FTL | ferritin, light polypeptide | -0.0313413 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0306903 |
| HMGA2 | high mobility group AT-hook 2 | -0.030343 |
| EGFR | epidermal growth factor receptor | -0.0298548 |
| RCOR1 | REST corepressor 1 | -0.0295732 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0292896 |
| FOXO1 | forkhead box O1 | -0.0277677 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0275593 |
| MECOM | MDS1 and EVI1 complex locus | -0.0267371 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265533 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0252146 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0248816 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0247152 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0246127 |
| RPS13 | ribosomal protein S13 | -0.0240668 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0240284 |
| THBD | thrombomodulin | -0.0238332 |
| JMJD1C | jumonji domain containing 1C | -0.0237938 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0237824 |
| EXOC4 | exocyst complex component 4 | -0.0237676 |
| CDK13 | cyclin-dependent kinase 13 | -0.0236954 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0235229 |
| HMGA1 | high mobility group AT-hook 1 | -0.023395 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0232996 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0232347 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0231901 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0231701 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0229919 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0226774 |
| CORO2A | coronin, actin binding protein, 2A | -0.0225372 |
| RAI14 | retinoic acid induced 14 | -0.022528 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0222355 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0220923 |
| EXT1 | exostosin glycosyltransferase 1 | -0.022092 |
| TJP1 | tight junction protein 1 | -0.0220844 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0220501 |
| RPS25 | ribosomal protein S25 | -0.0220446 |
| FBXO11 | F-box protein 11 | -0.0219989 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0219189 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0215872 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0212966 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0212637 |
| MT1E | metallothionein 1E | -0.0209217 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.020891 |
| DHFR | dihydrofolate reductase | -0.0208068 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0207844 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0207579 |
| ATM | ATM serine/threonine kinase | -0.0202736 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.020241 |
| GOLGB1 | golgin B1 | -0.0202058 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0200643 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0200282 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0200106 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0199808 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.019889 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0198861 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0198653 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0196697 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0195645 |
| PCDH1 | protocadherin 1 | -0.0194961 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0194044 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.019275 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0189908 |
