| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.264962 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.202581 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.154172 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.121491 |
| ATP13A3 | ATPase type 13A3 | 0.114256 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0953699 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0917983 |
| ZNF841 | zinc finger protein 841 | 0.0693907 |
| ADM | adrenomedullin | 0.0683313 |
| SET | SET nuclear proto-oncogene | 0.0668369 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0569823 |
| NUP58 | nucleoporin 58 | 0.0546801 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0540329 |
| PGK1 | phosphoglycerate kinase 1 | 0.050281 |
| TGFB2 | transforming growth factor, beta 2 | 0.0498987 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0495821 |
| PLK2 | polo-like kinase 2 | 0.0480023 |
| TMSB4X | thymosin beta 4, X-linked | 0.047291 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0467615 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0459967 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0436902 |
| PLIN2 | perilipin 2 | 0.0420398 |
| MSN | moesin | 0.0416782 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.041372 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0412696 |
| H1-4 | H1.4 linker histone, cluster member | 0.040897 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0406476 |
| ENO1 | enolase 1, (alpha) | 0.0396116 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0384592 |
| RAI1 | retinoic acid induced 1 | 0.0382091 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0379906 |
| ZNF292 | zinc finger protein 292 | 0.0376686 |
| TPM3 | tropomyosin 3 | 0.0360338 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0358073 |
| PDS5B | PDS5 cohesin associated factor B | 0.0351396 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0347255 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0336338 |
| CALR | calreticulin | 0.0332807 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0328537 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0326726 |
| STC2 | stanniocalcin 2 | 0.0326447 |
| TPD52 | tumor protein D52 | 0.0325938 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0323723 |
| CCNL1 | cyclin L1 | 0.031782 |
| ZNF148 | zinc finger protein 148 | 0.0313204 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0303301 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0297411 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0296821 |
| PLEC | plectin | 0.029438 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0291595 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0288545 |
| NCKAP1 | NCK-associated protein 1 | 0.028668 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.028601 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0285821 |
| RBM26 | RNA binding motif protein 26 | 0.0282531 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0281534 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0279131 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0277347 |
| XPO1 | exportin 1 | 0.0276097 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0275042 |
| HLTF | helicase-like transcription factor | 0.0274621 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0273485 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0271915 |
| CEP250 | centrosomal protein 250kDa | 0.0269198 |
| TFG | TRK-fused gene | 0.026734 |
| STK4 | serine/threonine kinase 4 | 0.0267148 |
| PKM | pyruvate kinase, muscle | 0.0266386 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.026253 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0258777 |
| SLC12A8 | solute carrier family 12, member 8 | 0.025821 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0256876 |
| ARRDC3 | arrestin domain containing 3 | 0.0256664 |
| POTEF | POTE ankyrin domain family, member F | 0.0255861 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0255007 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0253747 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.0252131 |
| AXL | AXL receptor tyrosine kinase | 0.0251733 |
| STMN1 | stathmin 1 | 0.0250729 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0249108 |
| MKI67 | marker of proliferation Ki-67 | 0.0247117 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.024702 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.024633 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.0246287 |
| USP3 | ubiquitin specific peptidase 3 | 0.0245741 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0245663 |
| NUP153 | nucleoporin 153kDa | 0.0245237 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0245118 |
| DENND5A | DENN/MADD domain containing 5A | 0.0245084 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0244106 |
| RTN4 | reticulon 4 | 0.023771 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0232852 |
| SULF1 | sulfatase 1 | 0.0232172 |
| RAB6A | RAB6A, member RAS oncogene family | 0.023056 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0228408 |
| RNF144B | ring finger protein 144B | 0.0227961 |
| SRP54 | signal recognition particle 54kDa | 0.0226976 |
| JUN | jun proto-oncogene | 0.022586 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0225796 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0224375 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0224023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.264028 |
| HLA-B | major histocompatibility complex, class I, B | -0.13533 |
| EXT1 | exostosin glycosyltransferase 1 | -0.134735 |
| FTL | ferritin, light polypeptide | -0.123483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119808 |
| FN1 | fibronectin 1 | -0.11535 |
| MT2A | metallothionein 2A | -0.0870071 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0867608 |
| INTS6 | integrator complex subunit 6 | -0.0851708 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0699694 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.068209 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0655087 |
| GLIS3 | GLIS family zinc finger 3 | -0.063651 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0540884 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0501975 |
| TLE4 | transducin-like enhancer of split 4 | -0.0484491 |
| FNDC3B | fibronectin type III domain containing 3B | -0.044691 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0443611 |
| RPS6 | ribosomal protein S6 | -0.0442243 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0435822 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.042917 |
| AHNAK | AHNAK nucleoprotein | -0.0418256 |
| CD44 | CD44 molecule (Indian blood group) | -0.040995 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0408795 |
| RPL35A | ribosomal protein L35a | -0.0407854 |
| NABP1 | nucleic acid binding protein 1 | -0.0403173 |
| ASPH | aspartate beta-hydroxylase | -0.0401062 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0398605 |
| HLA-C | major histocompatibility complex, class I, C | -0.0383077 |
| SMYD3 | SET and MYND domain containing 3 | -0.037367 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0370373 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0362389 |
| E2F3 | E2F transcription factor 3 | -0.0357752 |
| OSMR | oncostatin M receptor | -0.0351882 |
| RTN3 | reticulon 3 | -0.0334776 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0329973 |
| RPLP2 | ribosomal protein, large, P2 | -0.0324036 |
| TBCA | tubulin folding cofactor A | -0.0314172 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0313164 |
| RPL28 | ribosomal protein L28 | -0.030289 |
| RPLP1 | ribosomal protein, large, P1 | -0.0298844 |
| HMGB1 | high mobility group box 1 | -0.0297687 |
| FUS | FUS RNA binding protein | -0.0296361 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0296224 |
| PLSCR1 | phospholipid scramblase 1 | -0.0295303 |
| MT1X | metallothionein 1X | -0.0294041 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0291089 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0282891 |
| RPL12 | ribosomal protein L12 | -0.0281009 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0278975 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0277916 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0276957 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0276538 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0273699 |
| GOLGB1 | golgin B1 | -0.0270877 |
| UBAP2 | ubiquitin associated protein 2 | -0.0269179 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0266985 |
| IL6ST | interleukin 6 signal transducer | -0.0264111 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0263897 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0260933 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0260809 |
| RPS21 | ribosomal protein S21 | -0.0260686 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0255863 |
| RPS24 | ribosomal protein S24 | -0.0255627 |
| KLF12 | Kruppel-like factor 12 | -0.0255193 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0254206 |
| ACTG1 | actin gamma 1 | -0.0253771 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0253679 |
| RPL34 | ribosomal protein L34 | -0.0251399 |
| GNAS | GNAS complex locus | -0.024896 |
| ZNF804A | zinc finger protein 804A | -0.0248809 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0247383 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0246681 |
| RANBP17 | RAN binding protein 17 | -0.0246207 |
| CCND1 | cyclin D1 | -0.0244128 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0243782 |
| SDCBP | syndecan binding protein (syntenin) | -0.0243444 |
| ZNF432 | zinc finger protein 432 | -0.0243278 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0243103 |
| RPS23 | ribosomal protein S23 | -0.0242645 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0242258 |
| AEBP2 | AE binding protein 2 | -0.0239533 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.023879 |
| FOXP1 | forkhead box P1 | -0.0238024 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0237992 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.023783 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.023735 |
| RPL37 | ribosomal protein L37 | -0.0234009 |
| DENND1A | DENN/MADD domain containing 1A | -0.0233805 |
| DEK | DEK proto-oncogene | -0.0233453 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0232488 |
| CANX | calnexin | -0.0231748 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0230366 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0226738 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0225962 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0225744 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0224585 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.022382 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0223731 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.022236 |
