| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.248365 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.130269 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.106167 |
| HYOU1 | hypoxia up-regulated 1 | 0.101988 |
| PGK1 | phosphoglycerate kinase 1 | 0.0886415 |
| KRT18 | keratin 18, type I | 0.0807757 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0791187 |
| FAM13A | family with sequence similarity 13, member A | 0.0750741 |
| NPSR1 | neuropeptide S receptor 1 | 0.0707233 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0647254 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0622918 |
| PLEC | plectin | 0.061587 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0612467 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0601687 |
| TMSB4X | thymosin beta 4, X-linked | 0.0578915 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0550492 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0548136 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0485243 |
| ANLN | anillin, actin binding protein | 0.0483213 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0438083 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0434195 |
| ITGA6 | integrin, alpha 6 | 0.042385 |
| TES | testin LIM domain protein | 0.0412864 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0412331 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0398471 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0395077 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0393697 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0393643 |
| RPS2 | ribosomal protein S2 | 0.0387125 |
| DSPP | dentin sialophosphoprotein | 0.0385921 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0336718 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0334247 |
| HELZ | helicase with zinc finger | 0.0328301 |
| PRELID2 | PRELI domain containing 2 | 0.0327847 |
| SET | SET nuclear proto-oncogene | 0.0327269 |
| TMF1 | TATA element modulatory factor 1 | 0.0326184 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0321303 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0312532 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0312232 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0312229 |
| NUP58 | nucleoporin 58 | 0.0312071 |
| TPR | translocated promoter region, nuclear basket protein | 0.0311121 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0309486 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0309224 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0308007 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0306372 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0302666 |
| TPI1 | triosephosphate isomerase 1 | 0.0296869 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.029573 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0293168 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0289394 |
| LAMB3 | laminin, beta 3 | 0.0288586 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0287265 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0283708 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0276404 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0276076 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0275239 |
| CCNY | cyclin Y | 0.0266102 |
| GOLGA4 | golgin A4 | 0.0262705 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0262576 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0261687 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0258941 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0258909 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0256629 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0255339 |
| ZNF292 | zinc finger protein 292 | 0.0253596 |
| YEATS2 | YEATS domain containing 2 | 0.025348 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0251503 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0248329 |
| KRT19 | keratin 19, type I | 0.0248067 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0244619 |
| RPL3 | ribosomal protein L3 | 0.0240942 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0235454 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.023497 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0232657 |
| NCKAP1 | NCK-associated protein 1 | 0.0230354 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0227643 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0227238 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0223084 |
| HKDC1 | hexokinase domain containing 1 | 0.0219388 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0218752 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.0218661 |
| CLTC | clathrin, heavy chain (Hc) | 0.0217127 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0211866 |
| RAI1 | retinoic acid induced 1 | 0.0211018 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0210643 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0210638 |
| CPNE1 | copine I | 0.0210152 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0210035 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0209926 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0207718 |
| UBQLN1 | ubiquilin 1 | 0.0206619 |
| CEP57 | centrosomal protein 57kDa | 0.020654 |
| DST | dystonin | 0.0206525 |
| TMEM41B | transmembrane protein 41B | 0.0206007 |
| H1-4 | H1.4 linker histone, cluster member | 0.0201953 |
| RNF145 | ring finger protein 145 | 0.0201782 |
| TLN2 | talin 2 | 0.0200078 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0199888 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0199377 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.269676 |
| TMSB10 | thymosin beta 10 | -0.147299 |
| UBC | ubiquitin C | -0.120933 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.110096 |
| POTEF | POTE ankyrin domain family, member F | -0.100664 |
| EMP1 | epithelial membrane protein 1 | -0.0834702 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0787629 |
| RPS6 | ribosomal protein S6 | -0.0786992 |
| LMO7 | LIM domain 7 | -0.0782558 |
| ANXA2 | annexin A2 | -0.0750371 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0727951 |
| TXNRD1 | thioredoxin reductase 1 | -0.070409 |
| RPS27A | ribosomal protein S27a | -0.0636558 |
| PTMA | prothymosin, alpha | -0.0613389 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0608996 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0605654 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0587349 |
| RPL23 | ribosomal protein L23 | -0.0553881 |
| EZR | ezrin | -0.054726 |
| VMP1 | vacuole membrane protein 1 | -0.0509284 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0501495 |
| B2M | beta-2-microglobulin | -0.0499602 |
| ACTN4 | actinin, alpha 4 | -0.049665 |
| PCBP2 | poly(rC) binding protein 2 | -0.0488039 |
| FTL | ferritin, light polypeptide | -0.0487391 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0468039 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0463936 |
| RPL28 | ribosomal protein L28 | -0.0463311 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0434159 |
| SIK3 | SIK family kinase 3 | -0.0433918 |
| RPL35A | ribosomal protein L35a | -0.0433389 |
| DEK | DEK proto-oncogene | -0.0430899 |
| S100A10 | S100 calcium binding protein A10 | -0.0427171 |
| HMGB1 | high mobility group box 1 | -0.0425782 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0422863 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0420318 |
| TMC5 | transmembrane channel-like 5 | -0.0416789 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0413361 |
| BCL2L1 | BCL2-like 1 | -0.0412507 |
| AHNAK | AHNAK nucleoprotein | -0.0409847 |
| HLA-A | major histocompatibility complex, class I, A | -0.0407011 |
| H3-3B | H3.3 histone B | -0.0405251 |
| SEPTIN9 | septin 9 | -0.040435 |
| RPS21 | ribosomal protein S21 | -0.0400283 |
| S100A9 | S100 calcium binding protein A9 | -0.0386438 |
| RPLP1 | ribosomal protein, large, P1 | -0.0376907 |
| RPS25 | ribosomal protein S25 | -0.0369626 |
| HLA-B | major histocompatibility complex, class I, B | -0.0367705 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0360004 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0348803 |
| FUS | FUS RNA binding protein | -0.0347109 |
| LCN2 | lipocalin 2 | -0.0345899 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0345495 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0344422 |
| RPS24 | ribosomal protein S24 | -0.033975 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0336132 |
| AGR2 | anterior gradient 2 | -0.0323597 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0321748 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0317385 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0317231 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0314595 |
| AOPEP | aminopeptidase O (putative) | -0.0313173 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0312389 |
| CDK6 | cyclin-dependent kinase 6 | -0.0311031 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0310722 |
| HMGA1 | high mobility group AT-hook 1 | -0.0309662 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.030393 |
| COBL | cordon-bleu WH2 repeat protein | -0.0303321 |
| H1-0 | H1.0 linker histone | -0.0299107 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0294996 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0294552 |
| MUC1 | mucin 1, cell surface associated | -0.0293993 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0293212 |
| MYO1D | myosin ID | -0.0292467 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0290347 |
| RPL8 | ribosomal protein L8 | -0.0289831 |
| JUN | jun proto-oncogene | -0.0285241 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0283546 |
| CD2AP | CD2-associated protein | -0.0282201 |
| RPL38 | ribosomal protein L38 | -0.0281312 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0279113 |
| TUBA1B | tubulin, alpha 1b | -0.0274646 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0274008 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0272334 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0269303 |
| RHOA | ras homolog family member A | -0.0266941 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0265865 |
| GSTP1 | glutathione S-transferase pi 1 | -0.026536 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0264638 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0264624 |
| IER3 | immediate early response 3 | -0.0263943 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0262284 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0262154 |
| HLA-E | major histocompatibility complex, class I, E | -0.0260824 |
| CLDN7 | claudin 7 | -0.0260516 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0259801 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0259738 |
| ATF5 | activating transcription factor 5 | -0.0259053 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0257989 |
| TMEM123 | transmembrane protein 123 | -0.0256524 |
