| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.249471 |
| NUP58 | nucleoporin 58 | 0.119729 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.113978 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0909552 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0906494 |
| RPS12 | ribosomal protein S12 | 0.0843695 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0830015 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.075019 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0745431 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0728088 |
| SPAG9 | sperm associated antigen 9 | 0.0712951 |
| PGK1 | phosphoglycerate kinase 1 | 0.0691249 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0679695 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0679482 |
| RPS2 | ribosomal protein S2 | 0.0641678 |
| ZNF292 | zinc finger protein 292 | 0.0637703 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0610445 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0603506 |
| FLNA | filamin A, alpha | 0.0596983 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0579637 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0576695 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0572741 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0556181 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0556017 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0549208 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0539358 |
| EFNA5 | ephrin-A5 | 0.0536028 |
| SET | SET nuclear proto-oncogene | 0.0495817 |
| ATP13A3 | ATPase type 13A3 | 0.0495462 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0493663 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.049362 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0489458 |
| RPL4 | ribosomal protein L4 | 0.0480428 |
| RPL37A | ribosomal protein L37a | 0.0473313 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0469346 |
| ASPH | aspartate beta-hydroxylase | 0.0455283 |
| RAB8B | RAB8B, member RAS oncogene family | 0.044769 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0444734 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0440999 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0440801 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0440094 |
| RPL23 | ribosomal protein L23 | 0.0419968 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0414962 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.041399 |
| RPS17 | ribosomal protein S17 | 0.0409558 |
| HELZ | helicase with zinc finger | 0.0408689 |
| NDRG1 | N-myc downstream regulated 1 | 0.0408092 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0408075 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0406668 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.040647 |
| ACTG1 | actin gamma 1 | 0.0405048 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0400758 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0399965 |
| MALT1 | MALT1 paracaspase | 0.0399877 |
| WDR45B | WD repeat domain 45B | 0.0397635 |
| RPL3 | ribosomal protein L3 | 0.0387453 |
| PRKCE | protein kinase C, epsilon | 0.0375342 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0374634 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0373951 |
| SMAP1 | small ArfGAP 1 | 0.0372933 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0369339 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0367936 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.036088 |
| RPS3 | ribosomal protein S3 | 0.0360796 |
| RNF145 | ring finger protein 145 | 0.0360537 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0359498 |
| NCKAP1 | NCK-associated protein 1 | 0.0359491 |
| RPL26 | ribosomal protein L26 | 0.0357628 |
| CDC73 | cell division cycle 73 | 0.0355357 |
| MSN | moesin | 0.0353668 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0351707 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0351213 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0345796 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0340883 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0335484 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0331667 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0331637 |
| APP | amyloid beta (A4) precursor protein | 0.0331151 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0329792 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0328772 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0328125 |
| TPM3 | tropomyosin 3 | 0.0327369 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0324032 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0323078 |
| CORO1C | coronin, actin binding protein, 1C | 0.0322918 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0322693 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0322317 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0320569 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0317192 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0317074 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0310755 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0308542 |
| RUNX1 | runt-related transcription factor 1 | 0.0307624 |
| PRELID2 | PRELI domain containing 2 | 0.0306833 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0306328 |
| PKM | pyruvate kinase, muscle | 0.0301294 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0298427 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0295977 |
| CALD1 | caldesmon 1 | 0.0295911 |
| RYBP | RING1 and YY1 binding protein | 0.0290735 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.410553 |
| AHNAK | AHNAK nucleoprotein | -0.0927769 |
| MMP12 | matrix metallopeptidase 12 | -0.0856476 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.084342 |
| FTL | ferritin, light polypeptide | -0.0842529 |
| PTCHD4 | patched domain containing 4 | -0.0800745 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0728652 |
| VCL | vinculin | -0.068869 |
| NTM | neurotrimin | -0.0623883 |
| FOXP1 | forkhead box P1 | -0.0569287 |
| RPS6 | ribosomal protein S6 | -0.0566735 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0544532 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0527931 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0510871 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0508715 |
| TMSB10 | thymosin beta 10 | -0.0476689 |
| EGR1 | early growth response 1 | -0.0452702 |
| CTSB | cathepsin B | -0.0452141 |
| KYNU | kynureninase | -0.0432795 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0402869 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0388554 |
| KIAA1217 | KIAA1217 | -0.0387125 |
| RIGI | RNA sensor RIG-I | -0.0385127 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0383525 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0361878 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.035857 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0339337 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.033365 |
| RAI14 | retinoic acid induced 14 | -0.0322254 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0322042 |
| GPC6 | glypican 6 | -0.0319693 |
| VIM | vimentin | -0.0315604 |
| CDK6 | cyclin-dependent kinase 6 | -0.031397 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0308259 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0304399 |
| TXNRD1 | thioredoxin reductase 1 | -0.0299942 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0297782 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.0297353 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0296236 |
| ETV6 | ets variant 6 | -0.0295054 |
| BPTF | bromodomain PHD finger transcription factor | -0.029453 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0291228 |
| ZNF804A | zinc finger protein 804A | -0.0289256 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0280221 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0277699 |
| OSMR | oncostatin M receptor | -0.0275172 |
| LSAMP | limbic system-associated membrane protein | -0.0273688 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.027358 |
| GLIS3 | GLIS family zinc finger 3 | -0.0271964 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0266843 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0266714 |
| MAP4 | microtubule-associated protein 4 | -0.0263085 |
| RASAL2 | RAS protein activator like 2 | -0.0263065 |
| FBN2 | fibrillin 2 | -0.0261766 |
| POTEF | POTE ankyrin domain family, member F | -0.0257094 |
| EMP1 | epithelial membrane protein 1 | -0.025277 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0251816 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0251494 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0251433 |
| CUX1 | cut-like homeobox 1 | -0.0251167 |
| BNC2 | basonuclin 2 | -0.0250829 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0250086 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0249341 |
| TXNIP | thioredoxin interacting protein | -0.0248477 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0244215 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0243467 |
| MAP1B | microtubule-associated protein 1B | -0.024345 |
| RPS13 | ribosomal protein S13 | -0.0242524 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0242172 |
| ASTN2 | astrotactin 2 | -0.023512 |
| FMN1 | formin 1 | -0.0233789 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0232988 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0232483 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0231299 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0228919 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0228799 |
| CDK12 | cyclin-dependent kinase 12 | -0.0227844 |
| CAVIN1 | caveolae associated protein 1 | -0.0226508 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0224278 |
| NRP1 | neuropilin 1 | -0.0221042 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.021892 |
| RPL8 | ribosomal protein L8 | -0.0217017 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0215125 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0212909 |
| TNNC1 | troponin C type 1 (slow) | -0.0211788 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0210948 |
| WASF2 | WAS protein family, member 2 | -0.0210758 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0210081 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0209504 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0209283 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0208088 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0206746 |
| SBF2 | SET binding factor 2 | -0.0199763 |
| AEBP2 | AE binding protein 2 | -0.0199318 |
| PHF14 | PHD finger protein 14 | -0.019907 |
| RPS15 | ribosomal protein S15 | -0.0196956 |
| DNER | delta/notch-like EGF repeat containing | -0.019681 |
| H1-0 | H1.0 linker histone | -0.0196155 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0195934 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0193553 |
