| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.167802 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.140902 |
| NPSR1 | neuropeptide S receptor 1 | 0.13107 |
| NDRG1 | N-myc downstream regulated 1 | 0.111175 |
| EREG | epiregulin | 0.0971444 |
| FLNB | filamin B, beta | 0.0955579 |
| PGK1 | phosphoglycerate kinase 1 | 0.0950719 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0944137 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0934251 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0913543 |
| CCNY | cyclin Y | 0.0904676 |
| DSPP | dentin sialophosphoprotein | 0.0896745 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0890445 |
| TXNIP | thioredoxin interacting protein | 0.0840641 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0803871 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0775696 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0720498 |
| KRT18 | keratin 18, type I | 0.0706823 |
| PRELID2 | PRELI domain containing 2 | 0.0694746 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0670241 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0646598 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0634473 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0621843 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0613158 |
| ANXA2 | annexin A2 | 0.0600244 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0558284 |
| ITGA6 | integrin, alpha 6 | 0.0548664 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0516803 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0499927 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0497047 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0494012 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.049279 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0492576 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0489161 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0485407 |
| FNBP1L | formin binding protein 1-like | 0.0476838 |
| PTMA | prothymosin, alpha | 0.0445775 |
| CALB1 | calbindin 1, 28kDa | 0.0445737 |
| EZR | ezrin | 0.0442894 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0436804 |
| LRRC1 | leucine rich repeat containing 1 | 0.0434411 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0429047 |
| ZNF292 | zinc finger protein 292 | 0.0427302 |
| RNF217 | ring finger protein 217 | 0.0413761 |
| RNF145 | ring finger protein 145 | 0.0410969 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0405161 |
| NUP58 | nucleoporin 58 | 0.0402406 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0398692 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0396783 |
| COPA | coatomer protein complex, subunit alpha | 0.0387314 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0376785 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0373431 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370594 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0364273 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0363107 |
| FAT1 | FAT atypical cadherin 1 | 0.036149 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0361327 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0361321 |
| RPS2 | ribosomal protein S2 | 0.0360859 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0357909 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0354138 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0352049 |
| MED13L | mediator complex subunit 13-like | 0.0345859 |
| TPD52 | tumor protein D52 | 0.0344337 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0343082 |
| TMSB4X | thymosin beta 4, X-linked | 0.0337255 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0334833 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.033381 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0333683 |
| FERMT1 | fermitin family member 1 | 0.033257 |
| TPM4 | tropomyosin 4 | 0.0328244 |
| HELZ | helicase with zinc finger | 0.032611 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0325198 |
| MLEC | malectin | 0.0314865 |
| EPCAM | epithelial cell adhesion molecule | 0.0310555 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0307706 |
| EHF | ets homologous factor | 0.0304139 |
| SLK | STE20-like kinase | 0.0303897 |
| TFG | TRK-fused gene | 0.0302624 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0301979 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0300624 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0298292 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297978 |
| KIF5B | kinesin family member 5B | 0.0296947 |
| DENND1A | DENN/MADD domain containing 1A | 0.0293498 |
| RLF | rearranged L-myc fusion | 0.029243 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0291815 |
| BBX | bobby sox homolog (Drosophila) | 0.0289942 |
| CENPF | centromere protein F, 350/400kDa | 0.0289533 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0277214 |
| CALR | calreticulin | 0.0275924 |
| EXOC1 | exocyst complex component 1 | 0.0272021 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0271741 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0268861 |
| DNM2 | dynamin 2 | 0.0268597 |
| ANLN | anillin, actin binding protein | 0.0268213 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.026773 |
| LAMB3 | laminin, beta 3 | 0.0266243 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0262748 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.0262557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.327526 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.170062 |
| TMSB10 | thymosin beta 10 | -0.113488 |
| UBC | ubiquitin C | -0.105643 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0806651 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0767839 |
| RPS27A | ribosomal protein S27a | -0.0736928 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0628698 |
| POTEF | POTE ankyrin domain family, member F | -0.0563342 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0464918 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0454945 |
| MYO1E | myosin IE | -0.0453367 |
| FTL | ferritin, light polypeptide | -0.0452155 |
| AHNAK | AHNAK nucleoprotein | -0.0447526 |
| RPL23 | ribosomal protein L23 | -0.0437718 |
| CADPS | Ca++-dependent secretion activator | -0.0425964 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0406747 |
| H1-0 | H1.0 linker histone | -0.0395113 |
| RPS6 | ribosomal protein S6 | -0.0388466 |
| NEBL | nebulette | -0.0369129 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0364316 |
| PCBP2 | poly(rC) binding protein 2 | -0.0356666 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0350277 |
| TRIM2 | tripartite motif containing 2 | -0.0347939 |
| TXNRD1 | thioredoxin reductase 1 | -0.0343841 |
| PTEN | phosphatase and tensin homolog | -0.0330687 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0319555 |
| RPLP2 | ribosomal protein, large, P2 | -0.0314149 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0309581 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0298545 |
| RPLP1 | ribosomal protein, large, P1 | -0.0282282 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0280321 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0279606 |
| RPL12 | ribosomal protein L12 | -0.0274406 |
| GPHN | gephyrin | -0.0273002 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0271404 |
| CANX | calnexin | -0.0270501 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.026754 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0263988 |
| COG5 | component of oligomeric golgi complex 5 | -0.0261128 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0259355 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0258789 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.025756 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0257454 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0256431 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0256052 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0254869 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0251493 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.025104 |
| RPS24 | ribosomal protein S24 | -0.02506 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0247704 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.024636 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0242294 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.023882 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0236732 |
| HMGB1 | high mobility group box 1 | -0.0234231 |
| RPL28 | ribosomal protein L28 | -0.0230883 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0230724 |
| RPL8 | ribosomal protein L8 | -0.0230049 |
| CDK12 | cyclin-dependent kinase 12 | -0.0229774 |
| RBM25 | RNA binding motif protein 25 | -0.0228801 |
| MT2A | metallothionein 2A | -0.0227575 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.0224691 |
| RHOA | ras homolog family member A | -0.0223752 |
| RRBP1 | ribosome binding protein 1 | -0.0222136 |
| RPL5 | ribosomal protein L5 | -0.0221505 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0219703 |
| AHI1 | Abelson helper integration site 1 | -0.0219114 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.021861 |
| PCDHB16 | protocadherin beta 16 | -0.0218592 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0217042 |
| ATXN1 | ataxin 1 | -0.0215284 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0213089 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0212953 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0212934 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 | -0.0212272 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0211775 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0207941 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0205418 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.02044 |
| EPHB2 | EPH receptor B2 | -0.0203956 |
| EGR1 | early growth response 1 | -0.020004 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0199328 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0198186 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0197847 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0196099 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0196047 |
| RPS23 | ribosomal protein S23 | -0.0196033 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0195822 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0195674 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.019293 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0190393 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0190315 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0185557 |
| VMP1 | vacuole membrane protein 1 | -0.0185351 |
| COMMD10 | COMM domain containing 10 | -0.018464 |
| RPLP0 | ribosomal protein, large, P0 | -0.0184152 |
| ATF6 | activating transcription factor 6 | -0.0184061 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0183431 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0180821 |
