| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.203325 |
| PRELID2 | PRELI domain containing 2 | 0.126447 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.12113 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0716701 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0675046 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0631054 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0608935 |
| ZNF292 | zinc finger protein 292 | 0.0579993 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0576485 |
| RNF145 | ring finger protein 145 | 0.0568798 |
| RPS12 | ribosomal protein S12 | 0.0565232 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0549792 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0534113 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0524643 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0519621 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0515998 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0491216 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0490682 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0479007 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.046932 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0460178 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0453462 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0439389 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.043517 |
| RPS2 | ribosomal protein S2 | 0.0424537 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0419884 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0417951 |
| FAM13A | family with sequence similarity 13, member A | 0.041785 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0415992 |
| PTMA | prothymosin, alpha | 0.0413919 |
| MED13L | mediator complex subunit 13-like | 0.0412594 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0409478 |
| RPL3 | ribosomal protein L3 | 0.0394196 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0391215 |
| DSCAM | Down syndrome cell adhesion molecule | 0.038536 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0384236 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0382444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0382167 |
| RPL37A | ribosomal protein L37a | 0.038082 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0377872 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0375549 |
| RPS3 | ribosomal protein S3 | 0.0375409 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0371817 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0369754 |
| RPS8 | ribosomal protein S8 | 0.0369054 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0366829 |
| MYO6 | myosin VI | 0.0366048 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0356693 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0356294 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0352311 |
| FRMD5 | FERM domain containing 5 | 0.0345274 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0345191 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0341107 |
| FAT1 | FAT atypical cadherin 1 | 0.0338487 |
| TPR | translocated promoter region, nuclear basket protein | 0.03356 |
| CDC42SE2 | CDC42 small effector 2 | 0.0335125 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0331605 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0329943 |
| USP3 | ubiquitin specific peptidase 3 | 0.0328571 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0325651 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0324695 |
| RPS17 | ribosomal protein S17 | 0.0324689 |
| CALR | calreticulin | 0.0324504 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0323161 |
| JMJD1C | jumonji domain containing 1C | 0.032258 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0319024 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0318495 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0316507 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0316404 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315963 |
| HELZ | helicase with zinc finger | 0.0310164 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0309779 |
| PTK2 | protein tyrosine kinase 2 | 0.0307623 |
| GOLGA4 | golgin A4 | 0.0305352 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0305233 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0302958 |
| NFIA | nuclear factor I/A | 0.0301861 |
| SLTM | SAFB-like, transcription modulator | 0.0291399 |
| XPO1 | exportin 1 | 0.0288465 |
| MLEC | malectin | 0.0288258 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0288133 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0281464 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0279124 |
| ENO1 | enolase 1, (alpha) | 0.0278241 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0274615 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0273525 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0271845 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0270797 |
| EREG | epiregulin | 0.0269456 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0268888 |
| NUP58 | nucleoporin 58 | 0.0268508 |
| OGA | O-GlcNAcase | 0.0268413 |
| DENND4C | DENN/MADD domain containing 4C | 0.0264497 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0262474 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0260376 |
| CUL3 | cullin 3 | 0.0259965 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0259461 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0258842 |
| NCKAP1 | NCK-associated protein 1 | 0.0258098 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0258092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159219 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.154866 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.133687 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.113831 |
| LMO7 | LIM domain 7 | -0.106261 |
| FLNB | filamin B, beta | -0.0959667 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0854549 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.070224 |
| TJP1 | tight junction protein 1 | -0.0701355 |
| TXNRD1 | thioredoxin reductase 1 | -0.0697997 |
| MX1 | MX dynamin-like GTPase 1 | -0.0653324 |
| LAMA4 | laminin, alpha 4 | -0.0629103 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0627181 |
| RIGI | RNA sensor RIG-I | -0.0624053 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0614729 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0611618 |
| OXSR1 | oxidative stress responsive 1 | -0.0595951 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0579355 |
| MX2 | MX dynamin-like GTPase 2 | -0.056113 |
| POTEF | POTE ankyrin domain family, member F | -0.0560892 |
| SP100 | SP100 nuclear antigen | -0.0550872 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0550476 |
| RPL35A | ribosomal protein L35a | -0.0534695 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0517423 |
| ACTG1 | actin gamma 1 | -0.0515651 |
| MYO1E | myosin IE | -0.0506356 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0481995 |
| HLA-B | major histocompatibility complex, class I, B | -0.0472776 |
| ANXA2 | annexin A2 | -0.0470705 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0455984 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0455342 |
| MYOF | myoferlin | -0.0449213 |
| PLSCR1 | phospholipid scramblase 1 | -0.0442967 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0442294 |
| EGR1 | early growth response 1 | -0.0434788 |
| PRSS3 | protease, serine, 3 | -0.0415866 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0406797 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0400632 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0389011 |
| CLDN4 | claudin 4 | -0.0388919 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0382625 |
| RNF213 | ring finger protein 213 | -0.0377553 |
| RPS24 | ribosomal protein S24 | -0.0368195 |
| DSG3 | desmoglein 3 | -0.0366518 |
| RPS21 | ribosomal protein S21 | -0.0361979 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0357108 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0353258 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0348326 |
| VCL | vinculin | -0.0347179 |
| ATP10B | ATPase, class V, type 10B | -0.0342341 |
| TC2N | tandem C2 domains, nuclear | -0.034211 |
| KRT18 | keratin 18, type I | -0.0339296 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0339147 |
| RPLP0 | ribosomal protein, large, P0 | -0.0338952 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0335638 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0334563 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0327984 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0322385 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0315319 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0306602 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0303964 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0297242 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0295593 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0277782 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0276684 |
| RPL34 | ribosomal protein L34 | -0.0264696 |
| TMSB10 | thymosin beta 10 | -0.0264588 |
| S100A10 | S100 calcium binding protein A10 | -0.026388 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0262758 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0260403 |
| PERP | PERP, TP53 apoptosis effector | -0.0258964 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0257056 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.025622 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0255347 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0251065 |
| IER3 | immediate early response 3 | -0.0250616 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0249411 |
| NLRC5 | NLR family, CARD domain containing 5 | -0.0248769 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0245342 |
| MT2A | metallothionein 2A | -0.0242699 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0240439 |
| TRIM2 | tripartite motif containing 2 | -0.0238269 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0237466 |
| SH3D19 | SH3 domain containing 19 | -0.0236513 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0233783 |
| UBC | ubiquitin C | -0.0231307 |
| INO80 | INO80 complex subunit | -0.0228734 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0221059 |
| ACTN4 | actinin, alpha 4 | -0.0218869 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0214678 |
| PCDHB16 | protocadherin beta 16 | -0.0214372 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0211718 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0208351 |
| KRT19 | keratin 19, type I | -0.0207083 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0206859 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0206428 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0201836 |
| ATF6 | activating transcription factor 6 | -0.0201731 |
| DSG2 | desmoglein 2 | -0.0201153 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0200792 |
