| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0781153 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0699446 |
| PTMA | prothymosin, alpha | 0.0696861 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0602301 |
| RAI1 | retinoic acid induced 1 | 0.0539239 |
| SET | SET nuclear proto-oncogene | 0.0536775 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0452265 |
| CENPF | centromere protein F, 350/400kDa | 0.0436606 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0428191 |
| RPS12 | ribosomal protein S12 | 0.0402273 |
| PGK1 | phosphoglycerate kinase 1 | 0.0398048 |
| RPL37A | ribosomal protein L37a | 0.0396046 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0385654 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0367164 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.036463 |
| ANGPTL4 | angiopoietin-like 4 | 0.0360945 |
| CAPRIN2 | caprin family member 2 | 0.0355271 |
| TPM3 | tropomyosin 3 | 0.035459 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0353118 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0337772 |
| VIM | vimentin | 0.0336048 |
| RPL3 | ribosomal protein L3 | 0.0330866 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0329106 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0322499 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0314239 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0312643 |
| XPO1 | exportin 1 | 0.0312246 |
| RPS3 | ribosomal protein S3 | 0.030885 |
| YEATS2 | YEATS domain containing 2 | 0.0300538 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0298591 |
| TMSB4X | thymosin beta 4, X-linked | 0.0298427 |
| PLEC | plectin | 0.0297954 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0287714 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0281329 |
| CDK19 | cyclin-dependent kinase 19 | 0.0280293 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0278686 |
| MKI67 | marker of proliferation Ki-67 | 0.0278246 |
| DST | dystonin | 0.0276753 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0274105 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0273802 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0263693 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0263389 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0262557 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0257311 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0256956 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0254256 |
| RPL23 | ribosomal protein L23 | 0.0254162 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0253382 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0252432 |
| MT2A | metallothionein 2A | 0.0251889 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0251302 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0249799 |
| ENO1 | enolase 1, (alpha) | 0.0249552 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0244886 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0240468 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.023978 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0238999 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0234321 |
| MSN | moesin | 0.0234313 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0227058 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0226919 |
| PRELID2 | PRELI domain containing 2 | 0.0224693 |
| EZR | ezrin | 0.0218787 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0216977 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0216833 |
| RPL4 | ribosomal protein L4 | 0.0215934 |
| MOK | MOK protein kinase | 0.0214373 |
| SLK | STE20-like kinase | 0.0214251 |
| MYO10 | myosin X | 0.0214046 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0213395 |
| KLC1 | kinesin light chain 1 | 0.0210627 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0210464 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0205314 |
| RPL26 | ribosomal protein L26 | 0.0204549 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.019783 |
| FNIP1 | folliculin interacting protein 1 | 0.0197662 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.019724 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0196934 |
| ANLN | anillin, actin binding protein | 0.019616 |
| FLNB | filamin B, beta | 0.0196025 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0195151 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0194863 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.019472 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0194576 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0193058 |
| SMYD3 | SET and MYND domain containing 3 | 0.018985 |
| TPR | translocated promoter region, nuclear basket protein | 0.0187257 |
| CEP192 | centrosomal protein 192kDa | 0.0186877 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0186607 |
| TRERF1 | transcriptional regulating factor 1 | 0.0184345 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0181361 |
| CEP170 | centrosomal protein 170kDa | 0.018028 |
| TPM4 | tropomyosin 4 | 0.0180064 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0179863 |
| CEP250 | centrosomal protein 250kDa | 0.0179182 |
| HMGB2 | high mobility group box 2 | 0.017907 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0178617 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0178068 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0177656 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0176758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.57368 |
| TP63 | tumor protein p63 | -0.129826 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0761748 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0732268 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0681038 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0661398 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0657586 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0645799 |
| TMSB10 | thymosin beta 10 | -0.0636397 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0614792 |
| CD44 | CD44 molecule (Indian blood group) | -0.0588968 |
| FTL | ferritin, light polypeptide | -0.0588708 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0565674 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0558205 |
| CADM2 | cell adhesion molecule 2 | -0.0520914 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0488788 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0482646 |
| POTEF | POTE ankyrin domain family, member F | -0.0478645 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0466677 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0436744 |
| EGR1 | early growth response 1 | -0.0420536 |
| TNS3 | tensin 3 | -0.0418459 |
| MT1X | metallothionein 1X | -0.0405412 |
| HMGA1 | high mobility group AT-hook 1 | -0.0401837 |
| EHBP1 | EH domain binding protein 1 | -0.0362781 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0348336 |
| EPHA4 | EPH receptor A4 | -0.0339873 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0339777 |
| PLSCR1 | phospholipid scramblase 1 | -0.0335012 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0325793 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0325083 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0313902 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.030873 |
| TMEM123 | transmembrane protein 123 | -0.0306102 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0305918 |
| JUN | jun proto-oncogene | -0.0303396 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0300312 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0295231 |
| UBC | ubiquitin C | -0.029132 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0290196 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0275939 |
| HLA-B | major histocompatibility complex, class I, B | -0.0275822 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0273371 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0273281 |
| SP100 | SP100 nuclear antigen | -0.0272543 |
| INTS6 | integrator complex subunit 6 | -0.0262846 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0262313 |
| TAPBP | TAP binding protein (tapasin) | -0.0259854 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0257284 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0253324 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0250823 |
| GNAS | GNAS complex locus | -0.0244522 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0242405 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0242167 |
| TFRC | transferrin receptor | -0.0238397 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0235035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0232637 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.023244 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0232161 |
| NEK10 | NIMA-related kinase 10 | -0.023031 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0230017 |
| FUS | FUS RNA binding protein | -0.0226967 |
| ACTG1 | actin gamma 1 | -0.0225506 |
| RIGI | RNA sensor RIG-I | -0.0224431 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0220276 |
| VMP1 | vacuole membrane protein 1 | -0.0218227 |
| FBXO11 | F-box protein 11 | -0.0217706 |
| PDE10A | phosphodiesterase 10A | -0.0215885 |
| NPR2 | natriuretic peptide receptor 2 | -0.0208627 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0204282 |
| PRRC2B | proline-rich coiled-coil 2B | -0.020362 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0200048 |
| TGM2 | transglutaminase 2 | -0.0197901 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0193333 |
| BSG | basigin (Ok blood group) | -0.0192662 |
| CANX | calnexin | -0.0187753 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0187687 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0186094 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0185206 |
| LDHA | lactate dehydrogenase A | -0.0184115 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0183428 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.018212 |
| RPL28 | ribosomal protein L28 | -0.0181795 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0179316 |
| DNER | delta/notch-like EGF repeat containing | -0.0178162 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0178104 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0177524 |
| RPLP0 | ribosomal protein, large, P0 | -0.0177117 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0177025 |
| ASTN2 | astrotactin 2 | -0.0175222 |
| S100A9 | S100 calcium binding protein A9 | -0.0175133 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0173949 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0173288 |
| H1-0 | H1.0 linker histone | -0.0170691 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.017018 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.01697 |
| ARF1 | ADP-ribosylation factor 1 | -0.016704 |
| ANXA2 | annexin A2 | -0.01661 |
| RUNX1 | runt-related transcription factor 1 | -0.0165619 |
| RPL8 | ribosomal protein L8 | -0.0165472 |
