| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.155836 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.132355 |
| FAM13A | family with sequence similarity 13, member A | 0.101019 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0954482 |
| NAV2 | neuron navigator 2 | 0.0913848 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0886967 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0811596 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0758512 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0716771 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0713511 |
| PRELID2 | PRELI domain containing 2 | 0.0708047 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0674964 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0660138 |
| RPL4 | ribosomal protein L4 | 0.0658217 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0651395 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0590834 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0547514 |
| TMSB4X | thymosin beta 4, X-linked | 0.0545672 |
| PGK1 | phosphoglycerate kinase 1 | 0.0545433 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.053788 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0530996 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0485561 |
| FLNB | filamin B, beta | 0.048443 |
| ATP13A3 | ATPase type 13A3 | 0.0479821 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0479766 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0479606 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0470927 |
| RIOK3 | RIO kinase 3 | 0.046663 |
| PKM | pyruvate kinase, muscle | 0.0464295 |
| NGLY1 | N-glycanase 1 | 0.0453775 |
| MEF2A | myocyte enhancer factor 2A | 0.0453245 |
| PFKP | phosphofructokinase, platelet | 0.0449316 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0437656 |
| ANGPTL4 | angiopoietin-like 4 | 0.043758 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0419734 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0409141 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0408827 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0397877 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.039179 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0379132 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0376866 |
| RARB | retinoic acid receptor, beta | 0.0376272 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0373057 |
| RAI1 | retinoic acid induced 1 | 0.0372405 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0362769 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0362631 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0360591 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0346538 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0346396 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0346194 |
| FMNL2 | formin-like 2 | 0.0337605 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0336168 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0335437 |
| RUNX1 | runt-related transcription factor 1 | 0.0333526 |
| ENO1 | enolase 1, (alpha) | 0.0332535 |
| CA12 | carbonic anhydrase XII | 0.0332351 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0324069 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0318095 |
| SDC4 | syndecan 4 | 0.0312616 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0308204 |
| GPC6 | glypican 6 | 0.0307715 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0301991 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0301273 |
| ACTN4 | actinin, alpha 4 | 0.0297328 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0297177 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0296603 |
| FAM20C | family with sequence similarity 20, member C | 0.0293407 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0292229 |
| MYO1B | myosin IB | 0.0286989 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0286624 |
| YEATS2 | YEATS domain containing 2 | 0.0281976 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0278355 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0277997 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0277278 |
| PYGL | phosphorylase, glycogen, liver | 0.0275253 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0274265 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0272053 |
| ADD3 | adducin 3 (gamma) | 0.0269325 |
| CD109 | CD109 molecule | 0.0268468 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0267673 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0267314 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0267043 |
| FLNA | filamin A, alpha | 0.0266458 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0265654 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0264058 |
| PTK2 | protein tyrosine kinase 2 | 0.0263412 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0261073 |
| LOXL2 | lysyl oxidase-like 2 | 0.0256747 |
| EGFR | epidermal growth factor receptor | 0.0256409 |
| SETD5 | SET domain containing 5 | 0.0255621 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0255529 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0254937 |
| RPL37A | ribosomal protein L37a | 0.0254149 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0252437 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0251904 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0248458 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0247702 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0246697 |
| PRKCE | protein kinase C, epsilon | 0.0245378 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0245319 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.344492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110935 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.09303 |
| FTL | ferritin, light polypeptide | -0.0847613 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0751998 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0707844 |
| GLCCI1 | glucocorticoid induced 1 | -0.0704838 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0700986 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0692688 |
| CD44 | CD44 molecule (Indian blood group) | -0.068628 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0683346 |
| MT2A | metallothionein 2A | -0.064345 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0617722 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0585194 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0555953 |
| KYNU | kynureninase | -0.0548327 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0546345 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0533459 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0512079 |
| RBM39 | RNA binding motif protein 39 | -0.050468 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0500997 |
| NTN4 | netrin 4 | -0.0475173 |
| RPS6 | ribosomal protein S6 | -0.0466375 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0463448 |
| EGR1 | early growth response 1 | -0.0456924 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0419173 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0415185 |
| H1-0 | H1.0 linker histone | -0.0413585 |
| NRG1 | neuregulin 1 | -0.0400442 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0395862 |
| YBX3 | Y box binding protein 3 | -0.0391039 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0386496 |
| UBC | ubiquitin C | -0.0384228 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0381611 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0380368 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0362708 |
| RPS19 | ribosomal protein S19 | -0.0360525 |
| SYAP1 | synapse associated protein 1 | -0.0353226 |
| CANX | calnexin | -0.0343396 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0340214 |
| RPS21 | ribosomal protein S21 | -0.0339442 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0339084 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0338618 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0335161 |
| NDRG1 | N-myc downstream regulated 1 | -0.0333772 |
| IER3 | immediate early response 3 | -0.0329827 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0325259 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0321476 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0318482 |
| AADAC | arylacetamide deacetylase | -0.0312475 |
| LOX | lysyl oxidase | -0.0311974 |
| NRP1 | neuropilin 1 | -0.0304345 |
| TNNC1 | troponin C type 1 (slow) | -0.0300481 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0294244 |
| OSMR | oncostatin M receptor | -0.0293828 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0291949 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0289999 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0285363 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0284557 |
| NF1 | neurofibromin 1 | -0.0283215 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.028019 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278273 |
| RPS2 | ribosomal protein S2 | -0.0277333 |
| GLIS3 | GLIS family zinc finger 3 | -0.0270826 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0269265 |
| FNBP1 | formin binding protein 1 | -0.0266912 |
| NLK | nemo-like kinase | -0.0266669 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0258412 |
| NABP1 | nucleic acid binding protein 1 | -0.025636 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0253233 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0252873 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0252317 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0250641 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0248712 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0248637 |
| MED13L | mediator complex subunit 13-like | -0.0244237 |
| TXNIP | thioredoxin interacting protein | -0.024142 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0240637 |
| TMEM263 | transmembrane protein 263 | -0.0240446 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0238317 |
| KSR1 | kinase suppressor of ras 1 | -0.0238091 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0237715 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0237084 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0236784 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0236492 |
| RPL32 | ribosomal protein L32 | -0.0233354 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0231818 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0231203 |
| HDLBP | high density lipoprotein binding protein | -0.0229568 |
| VRK2 | vaccinia related kinase 2 | -0.0226901 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0225177 |
| NUMB | numb homolog (Drosophila) | -0.0225073 |
| FER | fer (fps/fes related) tyrosine kinase | -0.022239 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0222129 |
| RPL12 | ribosomal protein L12 | -0.0221872 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0220162 |
| MORF4L2 | mortality factor 4 like 2 | -0.0219451 |
| IL1R1 | interleukin 1 receptor, type I | -0.021934 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0217863 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0215827 |
