| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flumatinib (mesylate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | 0.129196 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.105343 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0915211 |
| EGFR | epidermal growth factor receptor | 0.0888966 |
| PTK2 | protein tyrosine kinase 2 | 0.0709417 |
| PTMA | prothymosin, alpha | 0.0702633 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0657263 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0548255 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0547915 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0528097 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0521662 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0510536 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0487445 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0474494 |
| FMNL2 | formin-like 2 | 0.0474246 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0472647 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0472524 |
| VIM | vimentin | 0.0470613 |
| NUP58 | nucleoporin 58 | 0.0470183 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0467455 |
| NRG1 | neuregulin 1 | 0.0462421 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0461555 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0460247 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0460097 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0457076 |
| CADM1 | cell adhesion molecule 1 | 0.0452324 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0450686 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0448923 |
| PGK1 | phosphoglycerate kinase 1 | 0.0441634 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0440056 |
| IRS2 | insulin receptor substrate 2 | 0.0437716 |
| YTHDC1 | YTH domain containing 1 | 0.0436745 |
| INHBA | inhibin, beta A | 0.0429805 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0424309 |
| CTBP2 | C-terminal binding protein 2 | 0.0417203 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0407423 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0407216 |
| TPM3 | tropomyosin 3 | 0.0404962 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0399102 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0398372 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0395206 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0389634 |
| APP | amyloid beta (A4) precursor protein | 0.0387376 |
| TMSB4X | thymosin beta 4, X-linked | 0.0380922 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0380073 |
| AHR | aryl hydrocarbon receptor | 0.0378485 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0376907 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0375483 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0372843 |
| RPL4 | ribosomal protein L4 | 0.0368106 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0364726 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0363843 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0360173 |
| NAV1 | neuron navigator 1 | 0.0359674 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0359575 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0357155 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0356264 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0355605 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0355134 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0353796 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0353483 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0353455 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0353341 |
| SMAD3 | SMAD family member 3 | 0.0352781 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0352531 |
| RORA | RAR-related orphan receptor A | 0.0350851 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0348908 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0348397 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0347674 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0347324 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.034409 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0343972 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0343783 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0342054 |
| NAV2 | neuron navigator 2 | 0.034185 |
| RBM33 | RNA binding motif protein 33 | 0.0340622 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0340479 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.033841 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0338218 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0336077 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.033375 |
| RAD51B | RAD51 paralog B | 0.0333716 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0330655 |
| PRKD3 | protein kinase D3 | 0.0329593 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0327973 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0323202 |
| PDE10A | phosphodiesterase 10A | 0.0321591 |
| TFG | TRK-fused gene | 0.0318751 |
| CCNY | cyclin Y | 0.031643 |
| FRMD4A | FERM domain containing 4A | 0.0316222 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0315965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0314268 |
| CD44 | CD44 molecule (Indian blood group) | 0.0314077 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0313284 |
| RPS10 | ribosomal protein S10 | 0.0312637 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0312588 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0311398 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0310978 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0309699 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0309186 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.197417 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.181037 |
| LAMB3 | laminin, beta 3 | -0.174776 |
| MYO1E | myosin IE | -0.166975 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.143076 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142854 |
| NDRG1 | N-myc downstream regulated 1 | -0.116516 |
| LMO7 | LIM domain 7 | -0.103375 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0981421 |
| ATOSA | atos homolog A | -0.0973342 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0958702 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0930248 |
| MXD1 | MAX dimerization protein 1 | -0.0854013 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0838312 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0815414 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0767626 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.075727 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0750143 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0742758 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0728346 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0726246 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0722404 |
| ABHD17C | abhydrolase domain containing 17C | -0.0716063 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0714861 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0677628 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0669124 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0636926 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0626311 |
| KYNU | kynureninase | -0.0622455 |
| FTL | ferritin, light polypeptide | -0.0620719 |
| RPS6 | ribosomal protein S6 | -0.061486 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0609811 |
| IGF2 | insulin-like growth factor 2 | -0.0604782 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0604081 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.058906 |
| GRB10 | growth factor receptor-bound protein 10 | -0.058245 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0581715 |
| FN1 | fibronectin 1 | -0.0555429 |
| RIGI | RNA sensor RIG-I | -0.055227 |
| KRT17 | keratin 17, type I | -0.0535409 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0523055 |
| ANXA1 | annexin A1 | -0.0521491 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0513072 |
| ANXA2 | annexin A2 | -0.0509155 |
| NPTN | neuroplastin | -0.0504906 |
| TJP1 | tight junction protein 1 | -0.0503594 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0497023 |
| PARD3 | par-3 family cell polarity regulator | -0.0495896 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0480455 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0479205 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0476947 |
| DOCK5 | dedicator of cytokinesis 5 | -0.046774 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0464283 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0459279 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0452294 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0450911 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0449406 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0439587 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0438919 |
| OSMR | oncostatin M receptor | -0.043464 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0434438 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0428713 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0425921 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0424228 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0424057 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0423448 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0414212 |
| LAMC2 | laminin, gamma 2 | -0.0413834 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0411706 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0407453 |
| KIAA1217 | KIAA1217 | -0.0405903 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.040391 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0403805 |
| TPM4 | tropomyosin 4 | -0.0401358 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0397045 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0396884 |
| RPL34 | ribosomal protein L34 | -0.0391633 |
| RPL28 | ribosomal protein L28 | -0.0386383 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0374423 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0371442 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0371243 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0366885 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0366314 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0363389 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0363248 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.03623 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0361377 |
| HLA-B | major histocompatibility complex, class I, B | -0.0355753 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0352486 |
| UBC | ubiquitin C | -0.0349417 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.034791 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.034747 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0346497 |
| MED13 | mediator complex subunit 13 | -0.0340576 |
| AHNAK | AHNAK nucleoprotein | -0.0336126 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0334075 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0332777 |
| S100A10 | S100 calcium binding protein A10 | -0.0330297 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0329775 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.032605 |
