| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.124442 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.104529 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0946247 |
| TPM3 | tropomyosin 3 | 0.0817649 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0772321 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0668977 |
| SET | SET nuclear proto-oncogene | 0.065729 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0644742 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0621768 |
| RPL4 | ribosomal protein L4 | 0.0618553 |
| PLEC | plectin | 0.0606962 |
| RPL3 | ribosomal protein L3 | 0.0571132 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0532058 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0507128 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0489696 |
| MKI67 | marker of proliferation Ki-67 | 0.0469472 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0438114 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0433047 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0431397 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0429396 |
| CEP250 | centrosomal protein 250kDa | 0.0424334 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0420463 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0413749 |
| GRAMD1B | GRAM domain containing 1B | 0.0413367 |
| PGK1 | phosphoglycerate kinase 1 | 0.0413177 |
| HDGF | hepatoma-derived growth factor | 0.0410521 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0381919 |
| KRT18 | keratin 18, type I | 0.0380849 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0379895 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0374311 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0374088 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0368504 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0366208 |
| TXNRD1 | thioredoxin reductase 1 | 0.0358788 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.035635 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0354346 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0353413 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0353387 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0351344 |
| ZNF292 | zinc finger protein 292 | 0.0337467 |
| XPOT | exportin, tRNA | 0.0333716 |
| OGA | O-GlcNAcase | 0.0330957 |
| ENO1 | enolase 1, (alpha) | 0.0330614 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0330508 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0329119 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0324661 |
| H1-4 | H1.4 linker histone, cluster member | 0.0324323 |
| PNN | pinin, desmosome associated protein | 0.0322382 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0309938 |
| PRPF6 | pre-mRNA processing factor 6 | 0.0307345 |
| KIF5B | kinesin family member 5B | 0.0304876 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0304014 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.030089 |
| CEP192 | centrosomal protein 192kDa | 0.0300347 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0297812 |
| XPO1 | exportin 1 | 0.0284344 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0277108 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0276094 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0273616 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0267368 |
| ATL2 | atlastin GTPase 2 | 0.0260036 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0259251 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0256051 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0255102 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0254952 |
| NUP58 | nucleoporin 58 | 0.0254593 |
| EPN2 | epsin 2 | 0.0253894 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0253412 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0252861 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0252194 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0252097 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0251284 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0242043 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0239975 |
| RPS18 | ribosomal protein S18 | 0.0239297 |
| RPL37A | ribosomal protein L37a | 0.0235536 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0235507 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0234972 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0234696 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0231585 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230353 |
| RBM33 | RNA binding motif protein 33 | 0.0229729 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0229346 |
| NONO | non-POU domain containing, octamer-binding | 0.0225516 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0225407 |
| RPS12 | ribosomal protein S12 | 0.022527 |
| SMAP1 | small ArfGAP 1 | 0.0222627 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0219295 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0217783 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0215649 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0214152 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0213872 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.0211255 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0211 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0210456 |
| TPI1 | triosephosphate isomerase 1 | 0.0210418 |
| APP | amyloid beta (A4) precursor protein | 0.021021 |
| PKM | pyruvate kinase, muscle | 0.020814 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0207558 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0205279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.455509 |
| EGR1 | early growth response 1 | -0.130384 |
| MCL1 | myeloid cell leukemia 1 | -0.0807901 |
| TMSB10 | thymosin beta 10 | -0.0728979 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0693661 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0680027 |
| NABP1 | nucleic acid binding protein 1 | -0.0662613 |
| YBX3 | Y box binding protein 3 | -0.0633253 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0575627 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0525822 |
| RPL12 | ribosomal protein L12 | -0.0523686 |
| NF1 | neurofibromin 1 | -0.0518392 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0502488 |
| RPLP1 | ribosomal protein, large, P1 | -0.0494534 |
| PTMA | prothymosin, alpha | -0.0488582 |
| INTS6 | integrator complex subunit 6 | -0.0480607 |
| CCNL1 | cyclin L1 | -0.0467457 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0462023 |
| PFN1 | profilin 1 | -0.0461521 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0455742 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0449617 |
| HMGA2 | high mobility group AT-hook 2 | -0.0448494 |
| RPS21 | ribosomal protein S21 | -0.0441194 |
| FTL | ferritin, light polypeptide | -0.0434577 |
| POTEF | POTE ankyrin domain family, member F | -0.0431444 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0430534 |
| VMP1 | vacuole membrane protein 1 | -0.0425857 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0425821 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0422168 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.040688 |
| RPS6 | ribosomal protein S6 | -0.040624 |
| HMGA1 | high mobility group AT-hook 1 | -0.0397384 |
| RPS15 | ribosomal protein S15 | -0.0392298 |
| FBXO11 | F-box protein 11 | -0.0384396 |
| ACTG1 | actin gamma 1 | -0.0383392 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0381742 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0380252 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0372431 |
| RPLP0 | ribosomal protein, large, P0 | -0.0366843 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0363196 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0362357 |
| CDK17 | cyclin-dependent kinase 17 | -0.0358447 |
| FMNL2 | formin-like 2 | -0.0357727 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0357005 |
| RPS19 | ribosomal protein S19 | -0.0355137 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0353145 |
| RPL35A | ribosomal protein L35a | -0.035144 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0347805 |
| NCOA7 | nuclear receptor coactivator 7 | -0.034503 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.033788 |
| OSMR | oncostatin M receptor | -0.033782 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0336007 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.033212 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0325718 |
| RPS29 | ribosomal protein S29 | -0.0321181 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0304891 |
| E2F3 | E2F transcription factor 3 | -0.030386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0296199 |
| AEBP2 | AE binding protein 2 | -0.0291259 |
| ATG7 | autophagy related 7 | -0.0291149 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0286883 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0286542 |
| RPL23 | ribosomal protein L23 | -0.0284722 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0283231 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0282474 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0282228 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0281546 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0279775 |
| BPTF | bromodomain PHD finger transcription factor | -0.0279567 |
| RPS8 | ribosomal protein S8 | -0.0277935 |
| RPL28 | ribosomal protein L28 | -0.027786 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0275959 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270948 |
| RSF1 | remodeling and spacing factor 1 | -0.0270276 |
| RPS14 | ribosomal protein S14 | -0.0269925 |
| ATF6 | activating transcription factor 6 | -0.0268938 |
| LRRC23 | leucine rich repeat containing 23 | -0.0268081 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0267491 |
| TUBA1B | tubulin, alpha 1b | -0.0266733 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0266436 |
| VCL | vinculin | -0.0265339 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0264475 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0263387 |
| ARF4 | ADP-ribosylation factor 4 | -0.0261783 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0256544 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0254805 |
| UBC | ubiquitin C | -0.0254036 |
| CDK12 | cyclin-dependent kinase 12 | -0.0252063 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0249905 |
| HMGB1 | high mobility group box 1 | -0.0249264 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0247476 |
| PTK2 | protein tyrosine kinase 2 | -0.0246935 |
| USP34 | ubiquitin specific peptidase 34 | -0.0244639 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0244119 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0242835 |
| SETX | senataxin | -0.0241989 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0240626 |
| THADA | thyroid adenoma associated | -0.0237783 |
| CUX1 | cut-like homeobox 1 | -0.0237618 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0237017 |
