| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.209762 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.153634 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.138932 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.125281 |
| LAMC2 | laminin, gamma 2 | 0.104558 |
| NDRG1 | N-myc downstream regulated 1 | 0.0979295 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0976996 |
| FAM13A | family with sequence similarity 13, member A | 0.0876683 |
| PGK1 | phosphoglycerate kinase 1 | 0.0823658 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0774352 |
| DSPP | dentin sialophosphoprotein | 0.0703899 |
| PLEC | plectin | 0.0700892 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0664375 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0653733 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0651612 |
| CALR | calreticulin | 0.0646822 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0637767 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0619962 |
| LAMB3 | laminin, beta 3 | 0.0605482 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0599254 |
| GRB10 | growth factor receptor-bound protein 10 | 0.058467 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0580205 |
| MSN | moesin | 0.057403 |
| LDHA | lactate dehydrogenase A | 0.0537307 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0536766 |
| TMSB4X | thymosin beta 4, X-linked | 0.0528019 |
| MYO6 | myosin VI | 0.052062 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0516242 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0513995 |
| ENO1 | enolase 1, (alpha) | 0.0503148 |
| ARRDC3 | arrestin domain containing 3 | 0.0489946 |
| NUP58 | nucleoporin 58 | 0.0489752 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0486298 |
| HMGB2 | high mobility group box 2 | 0.0460626 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0457982 |
| RPS12 | ribosomal protein S12 | 0.0441883 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0438098 |
| SET | SET nuclear proto-oncogene | 0.0428152 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.041986 |
| TPM3 | tropomyosin 3 | 0.0413781 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0409377 |
| ASPH | aspartate beta-hydroxylase | 0.0400053 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0393772 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0386273 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0381977 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0373322 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0371046 |
| RNF145 | ring finger protein 145 | 0.0369623 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0367107 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0366579 |
| TFG | TRK-fused gene | 0.0356555 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.034947 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0349206 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0342543 |
| CCNG2 | cyclin G2 | 0.0338735 |
| NCKAP1 | NCK-associated protein 1 | 0.0332046 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0327373 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0323317 |
| RPS2 | ribosomal protein S2 | 0.031111 |
| TOP1 | topoisomerase (DNA) I | 0.0306008 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0304931 |
| MKI67 | marker of proliferation Ki-67 | 0.0300892 |
| RPS3 | ribosomal protein S3 | 0.0298635 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0297982 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0289798 |
| YTHDC1 | YTH domain containing 1 | 0.0288679 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0288312 |
| HDGF | hepatoma-derived growth factor | 0.0287875 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0287837 |
| RPL3 | ribosomal protein L3 | 0.0287072 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.028426 |
| CD46 | CD46 molecule, complement regulatory protein | 0.028347 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0283062 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0282605 |
| PKM | pyruvate kinase, muscle | 0.0281962 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0280794 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0277838 |
| EPCAM | epithelial cell adhesion molecule | 0.0276479 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0274546 |
| FHIT | fragile histidine triad | 0.0273671 |
| ATP13A3 | ATPase type 13A3 | 0.0270219 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.026942 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0268288 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0260373 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.025552 |
| RNF213 | ring finger protein 213 | 0.0254782 |
| MXD1 | MAX dimerization protein 1 | 0.0252985 |
| ANXA5 | annexin A5 | 0.0252541 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0252046 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0251429 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0250664 |
| TMF1 | TATA element modulatory factor 1 | 0.0247934 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0246765 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0244027 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0243431 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0241086 |
| UPP1 | uridine phosphorylase 1 | 0.0240252 |
| RPS17 | ribosomal protein S17 | 0.023667 |
| RPL4 | ribosomal protein L4 | 0.0235325 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0231808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.343503 |
| POTEF | POTE ankyrin domain family, member F | -0.186286 |
| TMSB10 | thymosin beta 10 | -0.101772 |
| FTL | ferritin, light polypeptide | -0.101568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0808763 |
| RPL35A | ribosomal protein L35a | -0.0635787 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0614226 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0580051 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0567921 |
| RPS6 | ribosomal protein S6 | -0.055918 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0507839 |
| RPL8 | ribosomal protein L8 | -0.048131 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0477207 |
| ANXA2 | annexin A2 | -0.0477022 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0470062 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0468794 |
| RPL34 | ribosomal protein L34 | -0.0438424 |
| RPLP1 | ribosomal protein, large, P1 | -0.0435027 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0428219 |
| UBC | ubiquitin C | -0.042551 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0422165 |
| S100A10 | S100 calcium binding protein A10 | -0.0410885 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0404423 |
| EGR1 | early growth response 1 | -0.0386254 |
| RHOA | ras homolog family member A | -0.0352788 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0352429 |
| LMO7 | LIM domain 7 | -0.0341586 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0337444 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0332813 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0329652 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0325829 |
| RPLP0 | ribosomal protein, large, P0 | -0.0319702 |
| RPS21 | ribosomal protein S21 | -0.0311878 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0310772 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0309718 |
| CD2AP | CD2-associated protein | -0.0303455 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0302947 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0301686 |
| TMEM263 | transmembrane protein 263 | -0.0297729 |
| PALLD | palladin, cytoskeletal associated protein | -0.0297369 |
| RPL28 | ribosomal protein L28 | -0.0294701 |
| RPS23 | ribosomal protein S23 | -0.0288326 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0284546 |
| RPS15 | ribosomal protein S15 | -0.0283289 |
| H1-0 | H1.0 linker histone | -0.0276605 |
| RPLP2 | ribosomal protein, large, P2 | -0.0276001 |
| RLF | rearranged L-myc fusion | -0.0275689 |
| RPS24 | ribosomal protein S24 | -0.027404 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271468 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0270964 |
| TXNRD1 | thioredoxin reductase 1 | -0.0264552 |
| RASAL2 | RAS protein activator like 2 | -0.0263473 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0257359 |
| VCL | vinculin | -0.0255415 |
| FNIP1 | folliculin interacting protein 1 | -0.0255327 |
| SDC4 | syndecan 4 | -0.0252598 |
| KRT7 | keratin 7, type II | -0.025187 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0250277 |
| MAP4 | microtubule-associated protein 4 | -0.0250072 |
| JMJD1C | jumonji domain containing 1C | -0.0248777 |
| TJP1 | tight junction protein 1 | -0.0247435 |
| USP15 | ubiquitin specific peptidase 15 | -0.0246138 |
| ACTG1 | actin gamma 1 | -0.0243304 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0242636 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0240324 |
| F11R | F11 receptor | -0.0239887 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0237643 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0236851 |
| MYO1E | myosin IE | -0.0234215 |
| S100A9 | S100 calcium binding protein A9 | -0.0231491 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0228865 |
| HMGB1 | high mobility group box 1 | -0.0228206 |
| RPL38 | ribosomal protein L38 | -0.0227634 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0226337 |
| RPS13 | ribosomal protein S13 | -0.0225066 |
| HMGA1 | high mobility group AT-hook 1 | -0.0225035 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0223612 |
| ANKRD28 | ankyrin repeat domain 28 | -0.022207 |
| ARF4 | ADP-ribosylation factor 4 | -0.0219389 |
| SGMS2 | sphingomyelin synthase 2 | -0.0219115 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0217525 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0217161 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0216638 |
| MED13 | mediator complex subunit 13 | -0.0215985 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0214312 |
| TAPBP | TAP binding protein (tapasin) | -0.0214282 |
| CCND1 | cyclin D1 | -0.021372 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0212685 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.021084 |
| ATF6 | activating transcription factor 6 | -0.0206083 |
| RPS29 | ribosomal protein S29 | -0.0206025 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0204732 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0203396 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0203214 |
| KIAA0232 | KIAA0232 | -0.0202951 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0202824 |
| WASF2 | WAS protein family, member 2 | -0.0200037 |
| KLHL24 | kelch-like family member 24 | -0.0199842 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0199683 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0198305 |
