| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.207988 |
| FN1 | fibronectin 1 | 0.188152 |
| EGFR | epidermal growth factor receptor | 0.160293 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.137941 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.112649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.108454 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.103091 |
| MYO1E | myosin IE | 0.0998355 |
| SPAG9 | sperm associated antigen 9 | 0.098708 |
| NDRG1 | N-myc downstream regulated 1 | 0.0893292 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0892434 |
| CD44 | CD44 molecule (Indian blood group) | 0.0884244 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0842927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0838336 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0830314 |
| RTN4 | reticulon 4 | 0.0814641 |
| EFNA5 | ephrin-A5 | 0.0789087 |
| MRTFA | myocardin related transcription factor A | 0.0780743 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0755321 |
| USP34 | ubiquitin specific peptidase 34 | 0.0740425 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0702557 |
| NAV2 | neuron navigator 2 | 0.0687631 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0683146 |
| VIM | vimentin | 0.0678441 |
| ZNF292 | zinc finger protein 292 | 0.0644289 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0642112 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.063868 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0636044 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0633996 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0630068 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0627851 |
| ECT2 | epithelial cell transforming 2 | 0.061973 |
| ITGA6 | integrin, alpha 6 | 0.0618622 |
| SBF2 | SET binding factor 2 | 0.0614757 |
| SRP54 | signal recognition particle 54kDa | 0.0598875 |
| MT2A | metallothionein 2A | 0.0589967 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0587328 |
| B2M | beta-2-microglobulin | 0.0581198 |
| BBX | bobby sox homolog (Drosophila) | 0.0574214 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0568967 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0565478 |
| HDAC9 | histone deacetylase 9 | 0.0560574 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0557875 |
| MED13 | mediator complex subunit 13 | 0.0543172 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0535251 |
| DSCAM | Down syndrome cell adhesion molecule | 0.053426 |
| PCBP2 | poly(rC) binding protein 2 | 0.0525247 |
| RYBP | RING1 and YY1 binding protein | 0.0524458 |
| FMNL2 | formin-like 2 | 0.0524402 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0521194 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0504828 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0503256 |
| ZNF638 | zinc finger protein 638 | 0.0499539 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.049881 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0498037 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0468528 |
| HDLBP | high density lipoprotein binding protein | 0.046671 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0458785 |
| SLTM | SAFB-like, transcription modulator | 0.045722 |
| LMO7 | LIM domain 7 | 0.0457083 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0449319 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0446364 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0441254 |
| TXNRD1 | thioredoxin reductase 1 | 0.0440805 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0434669 |
| SCFD1 | sec1 family domain containing 1 | 0.0425954 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0417503 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0416348 |
| ZNF207 | zinc finger protein 207 | 0.0416231 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0408908 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0406282 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0403143 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0401583 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0397556 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0392529 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0386558 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0382347 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0382003 |
| UBC | ubiquitin C | 0.0380985 |
| TPM3 | tropomyosin 3 | 0.0375015 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0372802 |
| CDK19 | cyclin-dependent kinase 19 | 0.0372752 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0370683 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0368941 |
| XPO1 | exportin 1 | 0.0366573 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0365642 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0354525 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0354087 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0353947 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0353334 |
| FAM13A | family with sequence similarity 13, member A | 0.035282 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.034907 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0347772 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0347213 |
| FTL | ferritin, light polypeptide | 0.0345461 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0344563 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0343737 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0340645 |
| FNIP1 | folliculin interacting protein 1 | 0.0329993 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0325815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.14212 |
| SMYD3 | SET and MYND domain containing 3 | -0.131668 |
| VMP1 | vacuole membrane protein 1 | -0.109508 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0901043 |
| TENM3 | teneurin transmembrane protein 3 | -0.0790184 |
| RPL19 | ribosomal protein L19 | -0.0750578 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0742727 |
| RPS6 | ribosomal protein S6 | -0.0729233 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0728543 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0713581 |
| RPS8 | ribosomal protein S8 | -0.0713497 |
| PEG10 | paternally expressed 10 | -0.0711692 |
| RPL34 | ribosomal protein L34 | -0.0703734 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0700965 |
| RPS12 | ribosomal protein S12 | -0.066321 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0656495 |
| PRKCA | protein kinase C, alpha | -0.0650095 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0642382 |
| RPL13A | ribosomal protein L13a | -0.0628441 |
| NFIA | nuclear factor I/A | -0.0619941 |
| SQSTM1 | sequestosome 1 | -0.0598457 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.05935 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.059341 |
| VCL | vinculin | -0.0593265 |
| RPS19 | ribosomal protein S19 | -0.0593045 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0583904 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0576177 |
| MCL1 | myeloid cell leukemia 1 | -0.056873 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0539362 |
| DTNA | dystrobrevin, alpha | -0.0537746 |
| DIAPH2 | diaphanous-related formin 2 | -0.0532762 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0531838 |
| RPL38 | ribosomal protein L38 | -0.0529736 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0527254 |
| H3-3B | H3.3 histone B | -0.0525458 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0522789 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0519946 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0519079 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.051505 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0508024 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0507366 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0501587 |
| CD2AP | CD2-associated protein | -0.0492153 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.048786 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0482167 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0478264 |
| PDE10A | phosphodiesterase 10A | -0.0474945 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0468502 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.045385 |
| ACTG1 | actin gamma 1 | -0.0438961 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0432413 |
| ZFHX3 | zinc finger homeobox 3 | -0.0427082 |
| NABP1 | nucleic acid binding protein 1 | -0.0425571 |
| TMSB10 | thymosin beta 10 | -0.0423765 |
| BPTF | bromodomain PHD finger transcription factor | -0.0422202 |
| MYOF | myoferlin | -0.0422063 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0421505 |
| RPLP0 | ribosomal protein, large, P0 | -0.0418554 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0412492 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0410554 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0404856 |
| RPL7 | ribosomal protein L7 | -0.0404161 |
| COL5A1 | collagen, type V, alpha 1 | -0.0403349 |
| RPL9 | ribosomal protein L9 | -0.0402972 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0402655 |
| RAD51B | RAD51 paralog B | -0.0402515 |
| FRMD5 | FERM domain containing 5 | -0.0396458 |
| RPL35A | ribosomal protein L35a | -0.0395243 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0394459 |
| RPL12 | ribosomal protein L12 | -0.039358 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0390473 |
| CDH13 | cadherin 13 | -0.0380705 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0379411 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0377303 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0376206 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0375408 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0374342 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0369905 |
| EGR1 | early growth response 1 | -0.036902 |
| FLNB | filamin B, beta | -0.0358624 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0356667 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0356447 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0355936 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0353071 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0351925 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0351728 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0350469 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0347348 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0346875 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0345298 |
| TMEM123 | transmembrane protein 123 | -0.034371 |
| AHNAK | AHNAK nucleoprotein | -0.0339927 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0335151 |
| ARHGAP17 | Rho GTPase activating protein 17 | -0.0334319 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0333245 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.032915 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0326584 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0326176 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0325056 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0320778 |
