| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | 0.0946683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0654514 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0637618 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0573145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0465448 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0429158 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0415517 |
| DST | dystonin | 0.0400736 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0366049 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0360205 |
| TMSB4X | thymosin beta 4, X-linked | 0.0354789 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0336092 |
| KIF5B | kinesin family member 5B | 0.0305365 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0290669 |
| RPL4 | ribosomal protein L4 | 0.0289246 |
| CDC73 | cell division cycle 73 | 0.0287171 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0279862 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0269129 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0265753 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0255658 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0251808 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0251049 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0248904 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0248339 |
| PRR16 | proline rich 16 | 0.0245619 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0242561 |
| UTRN | utrophin | 0.0242062 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0236164 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.023606 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0235671 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0235127 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0230654 |
| PHF6 | PHD finger protein 6 | 0.0230331 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0229946 |
| CERT1 | ceramide transporter 1 | 0.0226694 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0220932 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0220191 |
| PCBP1 | poly(rC) binding protein 1 | 0.0218021 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0217645 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | 0.0216251 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0209659 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0208329 |
| TSEN15 | TSEN15 tRNA splicing endonuclease subunit | 0.020774 |
| FAM171B | family with sequence similarity 171, member B | 0.0206488 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0203965 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0203685 |
| CORO1C | coronin, actin binding protein, 1C | 0.0201945 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0200619 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0198782 |
| TGFB2 | transforming growth factor, beta 2 | 0.0198043 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0195672 |
| SLK | STE20-like kinase | 0.0195029 |
| FGF13 | fibroblast growth factor 13 | 0.0194672 |
| HMGA1 | high mobility group AT-hook 1 | 0.0194234 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0192985 |
| RANBP2 | RAN binding protein 2 | 0.0192666 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0192525 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0192365 |
| RPL3 | ribosomal protein L3 | 0.0191661 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0190055 |
| MITF | microphthalmia-associated transcription factor | 0.0189849 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0189339 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0188477 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 | 0.0187966 |
| TPM3 | tropomyosin 3 | 0.0185395 |
| FAM168A | family with sequence similarity 168, member A | 0.0184584 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.0184506 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0184039 |
| PLS3 | plastin 3 | 0.0183074 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0183043 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0182363 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0181773 |
| HEXB | hexosaminidase B (beta polypeptide) | 0.018103 |
| PDS5B | PDS5 cohesin associated factor B | 0.0180369 |
| LBR | lamin B receptor | 0.0179374 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0178423 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0178315 |
| PPL | periplakin | 0.0177308 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0176397 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0176326 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0176121 |
| JAM3 | junctional adhesion molecule 3 | 0.0174071 |
| MB21D2 | Mab-21 domain containing 2 | 0.0173209 |
| ABI2 | abl-interactor 2 | 0.0172258 |
| SERINC1 | serine incorporator 1 | 0.0171998 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0171704 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0171372 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.017125 |
| USP12 | ubiquitin specific peptidase 12 | 0.0171165 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0171162 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0169629 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0169568 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0169158 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0168915 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | 0.0168116 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0167894 |
| CCND1 | cyclin D1 | 0.016743 |
| ETV1 | ets variant 1 | 0.0166901 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0165558 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.016493 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.189264 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.143385 |
| PTMA | prothymosin, alpha | -0.102121 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0999877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0972979 |
| NTM | neurotrimin | -0.0920433 |
| RPS6 | ribosomal protein S6 | -0.0884361 |
| RPS16 | ribosomal protein S16 | -0.0873236 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0818648 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0778047 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0729357 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0704978 |
| ITGAV | integrin, alpha V | -0.0679434 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0677434 |
| SNX6 | sorting nexin 6 | -0.067049 |
| HDAC9 | histone deacetylase 9 | -0.0640678 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0624679 |
| PHIP | pleckstrin homology domain interacting protein | -0.0602942 |
| SRPK2 | SRSF protein kinase 2 | -0.0590624 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0585721 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0573942 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0573424 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0555564 |
| SRP54 | signal recognition particle 54kDa | -0.0549338 |
| RPS2 | ribosomal protein S2 | -0.0548658 |
| THOC2 | THO complex 2 | -0.0543003 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0533325 |
| GPC3 | glypican 3 | -0.0532017 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0529882 |
| POTEF | POTE ankyrin domain family, member F | -0.0516472 |
| TMSB10 | thymosin beta 10 | -0.0495015 |
| MAP4 | microtubule-associated protein 4 | -0.0494703 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0483454 |
| ZNF292 | zinc finger protein 292 | -0.0480559 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0479425 |
| RPS8 | ribosomal protein S8 | -0.0475826 |
| PRTG | protogenin | -0.0475323 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0468296 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0467781 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0459499 |
| TPR | translocated promoter region, nuclear basket protein | -0.0458781 |
| TFRC | transferrin receptor | -0.0458637 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.045515 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0455035 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0450315 |
| NKTR | natural killer cell triggering receptor | -0.0438782 |
| LPIN2 | lipin 2 | -0.0431591 |
| URI1 | URI1, prefoldin-like chaperone | -0.0424124 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0422375 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0415636 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.041534 |
| NOP58 | NOP58 ribonucleoprotein | -0.0414534 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0413638 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0412744 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0411324 |
| RPLP1 | ribosomal protein, large, P1 | -0.0404265 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0403712 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.040197 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0399263 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0397055 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0395479 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0393097 |
| GOLGA4 | golgin A4 | -0.0389329 |
| SMYD3 | SET and MYND domain containing 3 | -0.038718 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0382458 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.038242 |
| OGA | O-GlcNAcase | -0.0381846 |
| RAB31 | RAB31, member RAS oncogene family | -0.0374244 |
| GPATCH8 | G patch domain containing 8 | -0.0371031 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0370883 |
| UBC | ubiquitin C | -0.0370544 |
| SBF2 | SET binding factor 2 | -0.0368899 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0367041 |
| RBM39 | RNA binding motif protein 39 | -0.0366927 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0363848 |
| TENM3 | teneurin transmembrane protein 3 | -0.0360561 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0357906 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0355922 |
| APP | amyloid beta (A4) precursor protein | -0.0349176 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0347704 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.034693 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0346207 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0345867 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0344153 |
| TUT4 | terminal uridylyl transferase 4 | -0.0341038 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0340066 |
| ATXN2 | ataxin 2 | -0.0339338 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0335591 |
| SETD5 | SET domain containing 5 | -0.033116 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0329453 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0327203 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0325313 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0320657 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0318802 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0318799 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0318297 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0316501 |
| RPS12 | ribosomal protein S12 | -0.0316475 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0315858 |
| COG5 | component of oligomeric golgi complex 5 | -0.0313434 |
