| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.186413 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.122898 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.10985 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.102975 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0986897 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0979495 |
| PTMA | prothymosin, alpha | 0.0896461 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0891298 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0782339 |
| SEPTIN9 | septin 9 | 0.0757101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0751561 |
| FMNL2 | formin-like 2 | 0.0632429 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0617519 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0582209 |
| ATP13A3 | ATPase type 13A3 | 0.0569306 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0531255 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0515342 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0513858 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0503812 |
| SMAD3 | SMAD family member 3 | 0.0497631 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0488931 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.044101 |
| PLEC | plectin | 0.0437 |
| SPAG9 | sperm associated antigen 9 | 0.0435259 |
| ANGPTL4 | angiopoietin-like 4 | 0.0432879 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0425847 |
| SET | SET nuclear proto-oncogene | 0.0425811 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0378365 |
| RPL3 | ribosomal protein L3 | 0.0377613 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0363815 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0350905 |
| PRELID2 | PRELI domain containing 2 | 0.0350483 |
| APP | amyloid beta (A4) precursor protein | 0.0342406 |
| SNX14 | sorting nexin 14 | 0.0341986 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0341845 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0340664 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0336893 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0327868 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0326094 |
| PDE10A | phosphodiesterase 10A | 0.0322307 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0320304 |
| IPO7 | importin 7 | 0.0319589 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0314664 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0312987 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0312793 |
| MSN | moesin | 0.0312438 |
| TPM3 | tropomyosin 3 | 0.0305337 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0304503 |
| AFDN | afadin, adherens junction formation factor | 0.0304108 |
| NAV2 | neuron navigator 2 | 0.0300864 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0296651 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0294346 |
| ANLN | anillin, actin binding protein | 0.0294196 |
| XPO1 | exportin 1 | 0.0293098 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0288993 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0285549 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0285077 |
| CTBP2 | C-terminal binding protein 2 | 0.0284633 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0283887 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0283614 |
| RPS12 | ribosomal protein S12 | 0.0283346 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0281463 |
| ARRDC3 | arrestin domain containing 3 | 0.0280331 |
| DENND5A | DENN/MADD domain containing 5A | 0.0280275 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0279115 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.027683 |
| HYOU1 | hypoxia up-regulated 1 | 0.0274822 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0270157 |
| ACTN4 | actinin, alpha 4 | 0.0270107 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0267629 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0267386 |
| RPL4 | ribosomal protein L4 | 0.0265675 |
| AFAP1 | actin filament associated protein 1 | 0.0264297 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0256613 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253459 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.02532 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0249849 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0249112 |
| MED13L | mediator complex subunit 13-like | 0.0247638 |
| NCKAP1 | NCK-associated protein 1 | 0.0246796 |
| HPCAL1 | hippocalcin-like 1 | 0.024395 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0241719 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0241626 |
| RPS2 | ribosomal protein S2 | 0.0240923 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0239068 |
| PGK1 | phosphoglycerate kinase 1 | 0.0237262 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0235457 |
| NUP58 | nucleoporin 58 | 0.0234038 |
| HLTF | helicase-like transcription factor | 0.0231987 |
| TPD52 | tumor protein D52 | 0.023112 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0229924 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0229226 |
| MYOF | myoferlin | 0.0228642 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0228566 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0226374 |
| RPS3 | ribosomal protein S3 | 0.022527 |
| RBM26 | RNA binding motif protein 26 | 0.0225197 |
| DST | dystonin | 0.0223872 |
| OGA | O-GlcNAcase | 0.022225 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0221916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.339411 |
| RPS16 | ribosomal protein S16 | -0.191929 |
| RPL35A | ribosomal protein L35a | -0.0572468 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0545403 |
| EGR1 | early growth response 1 | -0.0508785 |
| FTL | ferritin, light polypeptide | -0.045522 |
| RPLP0 | ribosomal protein, large, P0 | -0.0455014 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0446145 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0432957 |
| RPLP1 | ribosomal protein, large, P1 | -0.0423229 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0404788 |
| RPS24 | ribosomal protein S24 | -0.0399867 |
| ZFP36 | ZFP36 ring finger protein | -0.037762 |
| TMSB10 | thymosin beta 10 | -0.0375372 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.037368 |
| ACTG1 | actin gamma 1 | -0.0350073 |
| VIM | vimentin | -0.0337078 |
| RPL38 | ribosomal protein L38 | -0.0324012 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0315305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0307334 |
| MED29 | mediator complex subunit 29 | -0.0292558 |
| ZNF546 | zinc finger protein 546 | -0.0289243 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.028041 |
| TXNRD1 | thioredoxin reductase 1 | -0.0279014 |
| RPL28 | ribosomal protein L28 | -0.0277987 |
| RPLP2 | ribosomal protein, large, P2 | -0.0277726 |
| OSMR | oncostatin M receptor | -0.0273707 |
| RPS6 | ribosomal protein S6 | -0.0273096 |
| CTSD | cathepsin D | -0.0272263 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0272239 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0270988 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0268854 |
| POTEF | POTE ankyrin domain family, member F | -0.0266621 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0261995 |
| TAPBP | TAP binding protein (tapasin) | -0.0260374 |
| MAP1B | microtubule-associated protein 1B | -0.0256299 |
| UBC | ubiquitin C | -0.0253993 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.025312 |
| RPS13 | ribosomal protein S13 | -0.025096 |
| ANXA2 | annexin A2 | -0.0248026 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0247315 |
| HMGA1 | high mobility group AT-hook 1 | -0.0240297 |
| GOLGB1 | golgin B1 | -0.023898 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0235098 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0232758 |
| AHNAK | AHNAK nucleoprotein | -0.0232745 |
| DEK | DEK proto-oncogene | -0.0232314 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.022881 |
| MT2A | metallothionein 2A | -0.0221283 |
| RPS21 | ribosomal protein S21 | -0.0220203 |
| FUS | FUS RNA binding protein | -0.0218306 |
| IER3 | immediate early response 3 | -0.0217514 |
| ZNF780B | zinc finger protein 780B | -0.0215952 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0213107 |
| HMGB1 | high mobility group box 1 | -0.0211399 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.020468 |
| HLA-B | major histocompatibility complex, class I, B | -0.0200816 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0198342 |
| RPS23 | ribosomal protein S23 | -0.0198011 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0195648 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) | -0.0193554 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0191182 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0191131 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0189769 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0189625 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0185378 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0182748 |
| PHF14 | PHD finger protein 14 | -0.0180866 |
| NPAS2 | neuronal PAS domain protein 2 | -0.01799 |
| FBXO11 | F-box protein 11 | -0.0176347 |
| NUP98 | nucleoporin 98kDa | -0.0176344 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0174455 |
| GNAS | GNAS complex locus | -0.0174239 |
| H1-0 | H1.0 linker histone | -0.0172143 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0171966 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0171743 |
| GLCCI1 | glucocorticoid induced 1 | -0.0170616 |
| RPL32 | ribosomal protein L32 | -0.0169455 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0167334 |
| ATF6 | activating transcription factor 6 | -0.0166776 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.016629 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0165781 |
| RPS15 | ribosomal protein S15 | -0.0165585 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0164629 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0164586 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0164143 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0164075 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0163791 |
| MYADM | myeloid-associated differentiation marker | -0.0163052 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0162723 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0162309 |
| RASAL2 | RAS protein activator like 2 | -0.01614 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0160629 |
| S100A10 | S100 calcium binding protein A10 | -0.0159542 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0158415 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0157539 |
| ATG7 | autophagy related 7 | -0.0157446 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0156744 |
| RPL12 | ribosomal protein L12 | -0.0156698 |
| RPS25 | ribosomal protein S25 | -0.0153268 |
