| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.165372 |
| LAMB3 | laminin, beta 3 | 0.147104 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103388 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0938594 |
| KRT17 | keratin 17, type I | 0.0901874 |
| LAMC2 | laminin, gamma 2 | 0.08867 |
| CALR | calreticulin | 0.0798204 |
| NAV2 | neuron navigator 2 | 0.0788934 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0779161 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0763551 |
| MYO6 | myosin VI | 0.0703835 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0682565 |
| DSPP | dentin sialophosphoprotein | 0.0675774 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0669358 |
| PLEC | plectin | 0.0663111 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0645708 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0637629 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0637481 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0627825 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0614484 |
| C3 | complement component 3 | 0.060296 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0584111 |
| SMAD3 | SMAD family member 3 | 0.0576136 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0575419 |
| TMSB4X | thymosin beta 4, X-linked | 0.057381 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0570442 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.05596 |
| KRT18 | keratin 18, type I | 0.0539588 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0534564 |
| AFDN | afadin, adherens junction formation factor | 0.0527756 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0507952 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.050095 |
| ATP13A3 | ATPase type 13A3 | 0.0500908 |
| KRT8 | keratin 8, type II | 0.0492998 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0481264 |
| H1-4 | H1.4 linker histone, cluster member | 0.0446746 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0428484 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0428077 |
| ARRDC3 | arrestin domain containing 3 | 0.0423995 |
| RPL3 | ribosomal protein L3 | 0.0401202 |
| LDHA | lactate dehydrogenase A | 0.0400465 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.039837 |
| SET | SET nuclear proto-oncogene | 0.039674 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0396553 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0391986 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0391678 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.039055 |
| PGK1 | phosphoglycerate kinase 1 | 0.0389231 |
| RPL4 | ribosomal protein L4 | 0.0389022 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0383696 |
| HMGB2 | high mobility group box 2 | 0.0381187 |
| MYO5B | myosin VB | 0.038106 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0380258 |
| LAMA4 | laminin, alpha 4 | 0.0379113 |
| RUNX1 | runt-related transcription factor 1 | 0.0376469 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.036968 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0369415 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.036914 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0368007 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0366079 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0363675 |
| ANO6 | anoctamin 6 | 0.0355652 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0353068 |
| VCL | vinculin | 0.0352244 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0350628 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0350398 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0348625 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0347023 |
| SEPTIN9 | septin 9 | 0.0345467 |
| DST | dystonin | 0.0339164 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0331251 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0330921 |
| KIAA1671 | KIAA1671 | 0.0330052 |
| CCNY | cyclin Y | 0.0328091 |
| PTK2 | protein tyrosine kinase 2 | 0.0326702 |
| XPO1 | exportin 1 | 0.0325755 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0325029 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0324206 |
| TFG | TRK-fused gene | 0.032288 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0321928 |
| TMF1 | TATA element modulatory factor 1 | 0.0321348 |
| THBS1 | thrombospondin 1 | 0.0320079 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0313355 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0313308 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0312282 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0311449 |
| PLAU | plasminogen activator, urokinase | 0.0311131 |
| HDGF | hepatoma-derived growth factor | 0.0305763 |
| TPM3 | tropomyosin 3 | 0.0305115 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.030505 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0304748 |
| FLNA | filamin A, alpha | 0.0301685 |
| FMNL2 | formin-like 2 | 0.0300552 |
| ECT2 | epithelial cell transforming 2 | 0.0298359 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0296721 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.029374 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0292096 |
| NUP58 | nucleoporin 58 | 0.0291101 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0287164 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0286973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.339089 |
| RPS6 | ribosomal protein S6 | -0.0876576 |
| HMGA1 | high mobility group AT-hook 1 | -0.0686339 |
| TMSB10 | thymosin beta 10 | -0.0675412 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.065166 |
| MT2A | metallothionein 2A | -0.0583156 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0554971 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0510657 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0465056 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0434939 |
| RPL34 | ribosomal protein L34 | -0.0428328 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.042556 |
| PTMA | prothymosin, alpha | -0.042261 |
| H1-0 | H1.0 linker histone | -0.0414706 |
| EGR1 | early growth response 1 | -0.0401226 |
| RPLP1 | ribosomal protein, large, P1 | -0.0400931 |
| FTL | ferritin, light polypeptide | -0.0399416 |
| AHNAK | AHNAK nucleoprotein | -0.0384541 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360919 |
| PLSCR1 | phospholipid scramblase 1 | -0.0360681 |
| RPS24 | ribosomal protein S24 | -0.0346927 |
| HMGB1 | high mobility group box 1 | -0.0333559 |
| RPS19 | ribosomal protein S19 | -0.033322 |
| ANXA2 | annexin A2 | -0.0318946 |
| YBX3 | Y box binding protein 3 | -0.0313961 |
| NRP1 | neuropilin 1 | -0.031353 |
| RPS15 | ribosomal protein S15 | -0.029996 |
| DEK | DEK proto-oncogene | -0.0293845 |
| EFNA5 | ephrin-A5 | -0.0286694 |
| MUC4 | mucin 4, cell surface associated | -0.0284592 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0283553 |
| RPL28 | ribosomal protein L28 | -0.0271216 |
| S100A9 | S100 calcium binding protein A9 | -0.0268809 |
| RPL12 | ribosomal protein L12 | -0.0260413 |
| DSG2 | desmoglein 2 | -0.0260317 |
| ARF4 | ADP-ribosylation factor 4 | -0.0250505 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0246098 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245679 |
| RPL35A | ribosomal protein L35a | -0.0242915 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0240839 |
| RPL8 | ribosomal protein L8 | -0.0236878 |
| RPLP0 | ribosomal protein, large, P0 | -0.0231754 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0230004 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0227782 |
| GNAS | GNAS complex locus | -0.0226484 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0216721 |
| RPS14 | ribosomal protein S14 | -0.0216352 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0214713 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0213329 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0212854 |
| RRBP1 | ribosome binding protein 1 | -0.0211008 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0210966 |
| HLA-C | major histocompatibility complex, class I, C | -0.0209581 |
| RHEB | Ras homolog enriched in brain | -0.0208879 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.02076 |
| GOLGB1 | golgin B1 | -0.0205211 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0201385 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0199545 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0199417 |
| H3-3B | H3.3 histone B | -0.0199409 |
| EFHD2 | EF-hand domain family, member D2 | -0.0198288 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0196013 |
| FRMD5 | FERM domain containing 5 | -0.0194086 |
| HLA-E | major histocompatibility complex, class I, E | -0.0192655 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0191364 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0191169 |
| TUBB | tubulin, beta class I | -0.0190761 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0189394 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.018551 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0183713 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0183173 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0181849 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0181345 |
| TMEM123 | transmembrane protein 123 | -0.0180402 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0178853 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.017625 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0175984 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0175684 |
| EMP1 | epithelial membrane protein 1 | -0.0174231 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0173806 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0171684 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0171067 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0169953 |
| GTF2B | general transcription factor IIB | -0.0169468 |
| S100A6 | S100 calcium binding protein A6 | -0.0169093 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0168825 |
| RPS21 | ribosomal protein S21 | -0.0168154 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0167875 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0165382 |
| OSMR | oncostatin M receptor | -0.0164934 |
| BTG3 | BTG family, member 3 | -0.0164706 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0164349 |
| IFI44 | interferon-induced protein 44 | -0.0163899 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0163834 |
| IER3 | immediate early response 3 | -0.0163274 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0160429 |
| ASTN2 | astrotactin 2 | -0.0160355 |
| UBC | ubiquitin C | -0.0158773 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0158158 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0158104 |
