| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.109101 |
| VGF | VGF nerve growth factor inducible | 0.099624 |
| PEG10 | paternally expressed 10 | 0.0966593 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0791228 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0768621 |
| LOC112694756 | uncharaterized LOC112694756 | 0.075146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0748442 |
| NDRG1 | N-myc downstream regulated 1 | 0.0709972 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0666486 |
| SET | SET nuclear proto-oncogene | 0.0631669 |
| PDE10A | phosphodiesterase 10A | 0.0627245 |
| MATR3 | matrin 3 | 0.0594464 |
| ENO1 | enolase 1, (alpha) | 0.055387 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.051446 |
| FAM13A | family with sequence similarity 13, member A | 0.0510472 |
| PGK1 | phosphoglycerate kinase 1 | 0.050278 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0487263 |
| RPL4 | ribosomal protein L4 | 0.0485972 |
| GRAMD4 | GRAM domain containing 4 | 0.047436 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0437406 |
| NUP58 | nucleoporin 58 | 0.0436932 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0435342 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0433392 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.043337 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0422645 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0421526 |
| CHGB | chromogranin B | 0.0416932 |
| STC1 | stanniocalcin 1 | 0.040662 |
| TPM3 | tropomyosin 3 | 0.0406532 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0404126 |
| ARGLU1 | arginine and glutamate rich 1 | 0.040382 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0386651 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0378986 |
| ZNF292 | zinc finger protein 292 | 0.037649 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0373747 |
| CPE | carboxypeptidase E | 0.0369195 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0364375 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0358379 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0352503 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0352171 |
| RPL3 | ribosomal protein L3 | 0.0342784 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0338184 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0337956 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0337861 |
| HMGB3 | high mobility group box 3 | 0.0329462 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0323634 |
| TSPYL2 | TSPY-like 2 | 0.0322011 |
| TMSB4X | thymosin beta 4, X-linked | 0.0318714 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0315399 |
| XPO1 | exportin 1 | 0.0310381 |
| FAT1 | FAT atypical cadherin 1 | 0.0307825 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0307062 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0300726 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0297237 |
| IRS2 | insulin receptor substrate 2 | 0.0292606 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0290404 |
| YY1AP1 | YY1 associated protein 1 | 0.0286381 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.028299 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0282199 |
| PNN | pinin, desmosome associated protein | 0.0281444 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0277791 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0277225 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0275376 |
| PKM | pyruvate kinase, muscle | 0.0273917 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0272288 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0269024 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0260987 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0260059 |
| NCKAP1 | NCK-associated protein 1 | 0.0258231 |
| RPS12 | ribosomal protein S12 | 0.0255945 |
| SPAG5 | sperm associated antigen 5 | 0.0253043 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0251217 |
| TMEM255B | transmembrane protein 255B | 0.0250622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.024876 |
| MTMR7 | myotubularin related protein 7 | 0.0244962 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0240675 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0239716 |
| JAM3 | junctional adhesion molecule 3 | 0.0239209 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0239132 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0238903 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0238712 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0236638 |
| AHR | aryl hydrocarbon receptor | 0.0235645 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0235515 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0234898 |
| CCNY | cyclin Y | 0.0233974 |
| PDS5B | PDS5 cohesin associated factor B | 0.0233109 |
| DTNA | dystrobrevin, alpha | 0.0231427 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0229833 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0228521 |
| KIF1A | kinesin family member 1A | 0.0228392 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0227561 |
| KIF5B | kinesin family member 5B | 0.0227438 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0226222 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0224466 |
| H1-4 | H1.4 linker histone, cluster member | 0.0224432 |
| VEGFA | vascular endothelial growth factor A | 0.022436 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0223891 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0220853 |
| ZNF395 | zinc finger protein 395 | 0.0220574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.159399 |
| TENM1 | teneurin transmembrane protein 1 | -0.136383 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.118902 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.108888 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0998823 |
| SNTG1 | syntrophin, gamma 1 | -0.0804312 |
| FTL | ferritin, light polypeptide | -0.0738361 |
| GPC6 | glypican 6 | -0.0708133 |
| GPC5 | glypican 5 | -0.0706647 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0699248 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0692285 |
| NRG1 | neuregulin 1 | -0.0683192 |
| PTCHD4 | patched domain containing 4 | -0.05892 |
| CALCA | calcitonin-related polypeptide alpha | -0.0578386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0545765 |
| SYT1 | synaptotagmin I | -0.0542043 |
| SMYD3 | SET and MYND domain containing 3 | -0.0535016 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0525098 |
| TXNRD1 | thioredoxin reductase 1 | -0.0506659 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0498186 |
| ZNF804A | zinc finger protein 804A | -0.0486486 |
| FGF14 | fibroblast growth factor 14 | -0.0483885 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0465874 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0464753 |
| NCKAP5 | NCK-associated protein 5 | -0.0449531 |
| TOX | thymocyte selection-associated high mobility group box | -0.044543 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.044348 |
| CNKSR3 | CNKSR family member 3 | -0.0442096 |
| RIT2 | Ras-like without CAAX 2 | -0.0430038 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0429304 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0423227 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0419669 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0415737 |
| EGR1 | early growth response 1 | -0.0411727 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0406756 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0398902 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.039581 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0394799 |
| UBB | ubiquitin B | -0.0372999 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0367009 |
| H1-0 | H1.0 linker histone | -0.0365089 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.035928 |
| WWOX | WW domain containing oxidoreductase | -0.0358848 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0342361 |
| GLCCI1 | glucocorticoid induced 1 | -0.0334939 |
| EFNA5 | ephrin-A5 | -0.0332144 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0331536 |
| TCF12 | transcription factor 12 | -0.0331252 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0329456 |
| LSAMP | limbic system-associated membrane protein | -0.0325151 |
| NBEA | neurobeachin | -0.0313147 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0310993 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.030949 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0307608 |
| FOXP1 | forkhead box P1 | -0.0304921 |
| EXOC4 | exocyst complex component 4 | -0.030481 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0302015 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0301762 |
| RPS6 | ribosomal protein S6 | -0.0298495 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0298058 |
| PHF14 | PHD finger protein 14 | -0.0296847 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0294716 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.029432 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0293924 |
| AGMO | alkylglycerol monooxygenase | -0.0293384 |
| PCDH9 | protocadherin 9 | -0.0291359 |
| HMGB1 | high mobility group box 1 | -0.0288992 |
| BPTF | bromodomain PHD finger transcription factor | -0.0288374 |
| DEK | DEK proto-oncogene | -0.0286435 |
| RPS16 | ribosomal protein S16 | -0.0285155 |
| RAD51B | RAD51 paralog B | -0.0281405 |
| RPL35A | ribosomal protein L35a | -0.0280728 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0279947 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0279407 |
| KIAA0825 | KIAA0825 | -0.0277588 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0274919 |
| RPL12 | ribosomal protein L12 | -0.027387 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0272634 |
| RALYL | RALY RNA binding protein-like | -0.0270188 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267132 |
| CENPF | centromere protein F, 350/400kDa | -0.0259885 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258508 |
| NKTR | natural killer cell triggering receptor | -0.0254481 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0252776 |
| FHIT | fragile histidine triad | -0.0252591 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0252202 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0252142 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0248879 |
| CNTNAP5 | contactin associated protein-like 5 | -0.024488 |
| S100A9 | S100 calcium binding protein A9 | -0.024298 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0239573 |
| SYT4 | synaptotagmin IV | -0.0239337 |
| TUBB | tubulin, beta class I | -0.023803 |
| MT2A | metallothionein 2A | -0.0236472 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.023628 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0234501 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.02341 |
| KIF26B | kinesin family member 26B | -0.0233664 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0231878 |
| NLGN1 | neuroligin 1 | -0.0229315 |
