| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.230532 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.169418 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.126229 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.12136 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121207 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.120643 |
| FN1 | fibronectin 1 | 0.113391 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.108967 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.10521 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0987027 |
| ZNF292 | zinc finger protein 292 | 0.0975019 |
| NAV2 | neuron navigator 2 | 0.0886288 |
| PGK1 | phosphoglycerate kinase 1 | 0.0868 |
| CADM1 | cell adhesion molecule 1 | 0.0836403 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0824983 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0781686 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0703107 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0681419 |
| MYOF | myoferlin | 0.0654045 |
| PDE10A | phosphodiesterase 10A | 0.0634685 |
| ARRDC3 | arrestin domain containing 3 | 0.062508 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0620441 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0609077 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0597814 |
| HELZ | helicase with zinc finger | 0.0590862 |
| SPAG9 | sperm associated antigen 9 | 0.0583855 |
| PRELID2 | PRELI domain containing 2 | 0.0562568 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0561418 |
| ATP13A3 | ATPase type 13A3 | 0.0557472 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0544044 |
| OGA | O-GlcNAcase | 0.0542722 |
| FMNL2 | formin-like 2 | 0.0526822 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.052508 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0520813 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.052074 |
| RPS12 | ribosomal protein S12 | 0.051113 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0509237 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0500456 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0480237 |
| MKI67 | marker of proliferation Ki-67 | 0.0474976 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0470293 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.046505 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0462501 |
| MSN | moesin | 0.04543 |
| RAI1 | retinoic acid induced 1 | 0.0444968 |
| CENPF | centromere protein F, 350/400kDa | 0.0443767 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0436318 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0435437 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0434961 |
| ANLN | anillin, actin binding protein | 0.0433286 |
| GOLGA4 | golgin A4 | 0.0428709 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0427682 |
| FLNB | filamin B, beta | 0.0407616 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.040035 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.03994 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0388443 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0388119 |
| OPTN | optineurin | 0.0371919 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0370799 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0366846 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0351439 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0351309 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.034563 |
| FNIP1 | folliculin interacting protein 1 | 0.034497 |
| YEATS2 | YEATS domain containing 2 | 0.0343441 |
| SNX9 | sorting nexin 9 | 0.0342573 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0338762 |
| FLNA | filamin A, alpha | 0.0337917 |
| FAM13A | family with sequence similarity 13, member A | 0.03285 |
| PCBP2 | poly(rC) binding protein 2 | 0.032738 |
| RTN4 | reticulon 4 | 0.0327153 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0324618 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0318522 |
| STC1 | stanniocalcin 1 | 0.0317489 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0310496 |
| SFTPA2 | surfactant protein A2 | 0.0302069 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0301657 |
| CEP250 | centrosomal protein 250kDa | 0.0301188 |
| TPM3 | tropomyosin 3 | 0.0297853 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0297412 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0296503 |
| SET | SET nuclear proto-oncogene | 0.028601 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0285991 |
| RPS2 | ribosomal protein S2 | 0.0282384 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0281899 |
| CCNL1 | cyclin L1 | 0.0273799 |
| KIF4A | kinesin family member 4A | 0.0271898 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0271615 |
| WTAP | Wilms tumor 1 associated protein | 0.0271294 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.027043 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0270175 |
| USP37 | ubiquitin specific peptidase 37 | 0.0265877 |
| XPO1 | exportin 1 | 0.0263585 |
| CDK19 | cyclin-dependent kinase 19 | 0.0262446 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0262345 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0258246 |
| B2M | beta-2-microglobulin | 0.0257358 |
| PKM | pyruvate kinase, muscle | 0.0257186 |
| APP | amyloid beta (A4) precursor protein | 0.0256989 |
| TPX2 | TPX2, microtubule-associated | 0.0256935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GLIS3 | GLIS family zinc finger 3 | -0.139653 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137809 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101795 |
| VCL | vinculin | -0.0955693 |
| BICC1 | BicC family RNA binding protein 1 | -0.0911461 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0842483 |
| IER3 | immediate early response 3 | -0.0812635 |
| HLA-B | major histocompatibility complex, class I, B | -0.0799666 |
| HMGA2 | high mobility group AT-hook 2 | -0.0727843 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0664128 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0616057 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0605049 |
| INTS6 | integrator complex subunit 6 | -0.0558154 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0554301 |
| FTL | ferritin, light polypeptide | -0.0536669 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0519661 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0495683 |
| TMSB10 | thymosin beta 10 | -0.04901 |
| CDH13 | cadherin 13 | -0.0485041 |
| PALLD | palladin, cytoskeletal associated protein | -0.0435402 |
| KYNU | kynureninase | -0.0434646 |
| HLA-A | major histocompatibility complex, class I, A | -0.0410487 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0406112 |
| EGR1 | early growth response 1 | -0.0384118 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0383788 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0360951 |
| AHNAK | AHNAK nucleoprotein | -0.0357941 |
| NABP1 | nucleic acid binding protein 1 | -0.0357659 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0336376 |
| RPL35A | ribosomal protein L35a | -0.0333297 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0322107 |
| CTSD | cathepsin D | -0.0318478 |
| NAV1 | neuron navigator 1 | -0.0302105 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0299899 |
| RPS24 | ribosomal protein S24 | -0.0289111 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0288551 |
| TPM1 | tropomyosin 1 (alpha) | -0.0287467 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0283133 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0282994 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0273359 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0270321 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0269214 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0267218 |
| NTN4 | netrin 4 | -0.025786 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0255601 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0254129 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0252564 |
| MAP1B | microtubule-associated protein 1B | -0.0247029 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.024611 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0245517 |
| GOLGB1 | golgin B1 | -0.0242186 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.023768 |
| VIM | vimentin | -0.0231874 |
| FAM20C | family with sequence similarity 20, member C | -0.0227359 |
| DIAPH2 | diaphanous-related formin 2 | -0.0226997 |
| ATG7 | autophagy related 7 | -0.0223725 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.022044 |
| OSMR | oncostatin M receptor | -0.0220416 |
| RAI14 | retinoic acid induced 14 | -0.0220276 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0217634 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0216846 |
| RAB31 | RAB31, member RAS oncogene family | -0.0215604 |
| SMAD2 | SMAD family member 2 | -0.0214317 |
| RPL36A | ribosomal protein L36a | -0.0212556 |
| CLMP | CXADR-like membrane protein | -0.0211237 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0210272 |
| HDAC9 | histone deacetylase 9 | -0.0209234 |
| ACTG1 | actin gamma 1 | -0.0209164 |
| TLE4 | transducin-like enhancer of split 4 | -0.020722 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0206631 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.020648 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0206075 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0205523 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0201098 |
| RPL38 | ribosomal protein L38 | -0.0200075 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0199142 |
| CNTN6 | contactin 6 | -0.019729 |
| RPL31 | ribosomal protein L31 | -0.0196011 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0195421 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0195273 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0195027 |
| RPS13 | ribosomal protein S13 | -0.0192552 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.01907 |
| RPLP2 | ribosomal protein, large, P2 | -0.0188412 |
| TRIM55 | tripartite motif containing 55 | -0.0187045 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0185641 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0184475 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0183536 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0181226 |
| UBC | ubiquitin C | -0.0179758 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.017865 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0177475 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0176488 |
| TUT7 | terminal uridylyl transferase 7 | -0.0176098 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0175705 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0174956 |
| HLA-E | major histocompatibility complex, class I, E | -0.0174053 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.017325 |
| CUX1 | cut-like homeobox 1 | -0.0172266 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.017125 |
