| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PGK1 | phosphoglycerate kinase 1 | 0.145606 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.116619 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.108554 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0977943 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0902378 |
| VIM | vimentin | 0.0884865 |
| FAM13A | family with sequence similarity 13, member A | 0.0876532 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0831457 |
| TMSB10 | thymosin beta 10 | 0.0761383 |
| SDC4 | syndecan 4 | 0.0699754 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0614999 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0604865 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0594275 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0586551 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0585595 |
| EFNA5 | ephrin-A5 | 0.057695 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0548482 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0521122 |
| RPL5 | ribosomal protein L5 | 0.0498399 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0496056 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0480484 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0472381 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0456743 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0444168 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0443623 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0442632 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0440985 |
| PCBP2 | poly(rC) binding protein 2 | 0.0440558 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0437015 |
| ATP13A3 | ATPase type 13A3 | 0.0434367 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0434049 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0431079 |
| WTAP | Wilms tumor 1 associated protein | 0.0430172 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0426106 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0425067 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0422414 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0421061 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0417665 |
| FN1 | fibronectin 1 | 0.0416023 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0415881 |
| FLOT1 | flotillin 1 | 0.0411216 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0403685 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0403089 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0402871 |
| USP3 | ubiquitin specific peptidase 3 | 0.0401089 |
| S100A6 | S100 calcium binding protein A6 | 0.0400821 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0400732 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0399604 |
| HLA-A | major histocompatibility complex, class I, A | 0.0398735 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0398026 |
| FTL | ferritin, light polypeptide | 0.0395302 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0395191 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.039158 |
| ANXA5 | annexin A5 | 0.0389653 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0388634 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0386219 |
| CDK17 | cyclin-dependent kinase 17 | 0.0383184 |
| ENO1 | enolase 1, (alpha) | 0.037823 |
| CAVIN1 | caveolae associated protein 1 | 0.0377126 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0375677 |
| ZNF292 | zinc finger protein 292 | 0.037303 |
| GDA | guanine deaminase | 0.0372899 |
| NAV2 | neuron navigator 2 | 0.0370813 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.037065 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0370195 |
| SPAG9 | sperm associated antigen 9 | 0.0368529 |
| LAMB3 | laminin, beta 3 | 0.0367377 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0360955 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0359152 |
| FNBP1L | formin binding protein 1-like | 0.0358698 |
| NEK7 | NIMA-related kinase 7 | 0.0355908 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0355726 |
| SQSTM1 | sequestosome 1 | 0.0353582 |
| IGF2 | insulin-like growth factor 2 | 0.0348051 |
| RPS12 | ribosomal protein S12 | 0.0345072 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0339905 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0339132 |
| PTK2 | protein tyrosine kinase 2 | 0.033902 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0336435 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0334849 |
| QKI | QKI, KH domain containing, RNA binding | 0.032902 |
| MT1X | metallothionein 1X | 0.0325802 |
| VCAN | versican | 0.0324951 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0319628 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0319296 |
| CDC73 | cell division cycle 73 | 0.0318703 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0318136 |
| PRKD3 | protein kinase D3 | 0.0317967 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0314984 |
| RPLP1 | ribosomal protein, large, P1 | 0.0312675 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0312364 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0309317 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0307486 |
| TPR | translocated promoter region, nuclear basket protein | 0.030717 |
| B2M | beta-2-microglobulin | 0.0305775 |
| MATR3 | matrin 3 | 0.030526 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0304821 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0304646 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0302959 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0302716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.191196 |
| MT2A | metallothionein 2A | -0.139693 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.128885 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128555 |
| COL6A3 | collagen, type VI, alpha 3 | -0.105015 |
| GLIS3 | GLIS family zinc finger 3 | -0.0753638 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0690157 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0680563 |
| HMGA2 | high mobility group AT-hook 2 | -0.0646576 |
| NRXN3 | neurexin 3 | -0.0625978 |
| CALD1 | caldesmon 1 | -0.0616444 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0613255 |
| SMYD3 | SET and MYND domain containing 3 | -0.058003 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0574522 |
| ZNF395 | zinc finger protein 395 | -0.0528894 |
| SEC24D | SEC24 family member D | -0.0521406 |
| RAD51B | RAD51 paralog B | -0.0507991 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0490038 |
| CFDP1 | craniofacial development protein 1 | -0.0480205 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0467033 |
| CD44 | CD44 molecule (Indian blood group) | -0.0464007 |
| VEGFC | vascular endothelial growth factor C | -0.0448597 |
| VCL | vinculin | -0.043921 |
| VEGFA | vascular endothelial growth factor A | -0.0437095 |
| SETD5 | SET domain containing 5 | -0.0436352 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0433825 |
| TXNIP | thioredoxin interacting protein | -0.0432076 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0429717 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0427405 |
| SMAD3 | SMAD family member 3 | -0.042662 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.042241 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0422229 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0418608 |
| UBE4B | ubiquitination factor E4B | -0.0416165 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0413118 |
| ACTG1 | actin gamma 1 | -0.0412359 |
| H3-3B | H3.3 histone B | -0.0409971 |
| CALU | calumenin | -0.0401165 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.039492 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0378606 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0377861 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0371358 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0371172 |
| RTN4 | reticulon 4 | -0.0370881 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0370807 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0369696 |
| CDK6 | cyclin-dependent kinase 6 | -0.0367704 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0367111 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.036472 |
| RNF24 | ring finger protein 24 | -0.0364027 |
| HDLBP | high density lipoprotein binding protein | -0.0362652 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0355968 |
| EGFR | epidermal growth factor receptor | -0.035473 |
| SNX29 | sorting nexin 29 | -0.0350249 |
| RCOR1 | REST corepressor 1 | -0.0342424 |
| NAV1 | neuron navigator 1 | -0.0342159 |
| LOX | lysyl oxidase | -0.0341489 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0338923 |
| FHIT | fragile histidine triad | -0.033764 |
| SLC35F5 | solute carrier family 35, member F5 | -0.0331959 |
| TVP23C-CDRT4 | TVP23C-CDRT4 readthrough | -0.0330813 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0329338 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0327439 |
| FRMD6 | FERM domain containing 6 | -0.0326516 |
| GSE1 | Gse1 coiled-coil protein | -0.0321488 |
| STC1 | stanniocalcin 1 | -0.0315357 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.031499 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0314728 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0313666 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0313162 |
| PRKCA | protein kinase C, alpha | -0.0312354 |
| ATXN1 | ataxin 1 | -0.0311516 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0308073 |
| CLIC4 | chloride intracellular channel 4 | -0.0307134 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0306744 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0306124 |
| EXOC4 | exocyst complex component 4 | -0.0303827 |
| SCFD2 | sec1 family domain containing 2 | -0.0299178 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0298548 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0297917 |
| FAM13B | family with sequence similarity 13, member B | -0.0296666 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0293889 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.029331 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0293076 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0291138 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0289503 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0288465 |
| RASAL2 | RAS protein activator like 2 | -0.0286173 |
| CABIN1 | calcineurin binding protein 1 | -0.0283598 |
| MTPN | myotrophin | -0.0282249 |
| PRELID2 | PRELI domain containing 2 | -0.0282224 |
| BSG | basigin (Ok blood group) | -0.0279558 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0277407 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.027471 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0273783 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0273761 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0273566 |
| TGFB1 | transforming growth factor, beta 1 | -0.027328 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0270562 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0270134 |
