| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0951058 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0648937 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0518238 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0467933 |
| FTL | ferritin, light polypeptide | 0.0460769 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0414602 |
| NCKAP1 | NCK-associated protein 1 | 0.0359187 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0347 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0328422 |
| TFG | TRK-fused gene | 0.0326102 |
| SET | SET nuclear proto-oncogene | 0.0324823 |
| RPS12 | ribosomal protein S12 | 0.0313912 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0296761 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.029424 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0289692 |
| MATR3 | matrin 3 | 0.0273922 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0265451 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0264906 |
| RPS3 | ribosomal protein S3 | 0.0262167 |
| GOLGA4 | golgin A4 | 0.0255319 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0248646 |
| ZNF292 | zinc finger protein 292 | 0.0246371 |
| RBM25 | RNA binding motif protein 25 | 0.0244027 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0243818 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0240335 |
| RNF145 | ring finger protein 145 | 0.0239068 |
| RPL18 | ribosomal protein L18 | 0.0235634 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226551 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0226182 |
| RPL37A | ribosomal protein L37a | 0.0221048 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0220771 |
| RPS2 | ribosomal protein S2 | 0.0219316 |
| CST3 | cystatin C | 0.0216901 |
| HOXB6 | homeobox B6 | 0.0214621 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0212884 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0210565 |
| HYOU1 | hypoxia up-regulated 1 | 0.0205474 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0203309 |
| TMF1 | TATA element modulatory factor 1 | 0.0203101 |
| SPAG9 | sperm associated antigen 9 | 0.0200879 |
| RPS19 | ribosomal protein S19 | 0.0200413 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0198592 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0198223 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0198184 |
| RPL23 | ribosomal protein L23 | 0.019641 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0196314 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0193218 |
| CALR | calreticulin | 0.0193115 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0188738 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0188708 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0188341 |
| RPL36 | ribosomal protein L36 | 0.0187307 |
| NUP58 | nucleoporin 58 | 0.0186442 |
| USP3 | ubiquitin specific peptidase 3 | 0.0186199 |
| RPS17 | ribosomal protein S17 | 0.0186151 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0185995 |
| NPTN | neuroplastin | 0.0184979 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.018346 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0181493 |
| HMGB2 | high mobility group box 2 | 0.0179408 |
| RNF114 | ring finger protein 114 | 0.0177193 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0175811 |
| FNBP1L | formin binding protein 1-like | 0.0173142 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0172128 |
| SEPTIN7 | septin 7 | 0.0170087 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.016901 |
| MED13L | mediator complex subunit 13-like | 0.0168906 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.016657 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0166202 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0165789 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0165716 |
| RPL13A | ribosomal protein L13a | 0.0164979 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0164001 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0163605 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0161873 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0161581 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0159781 |
| MLEC | malectin | 0.0159451 |
| KIF5B | kinesin family member 5B | 0.0158582 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0155192 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0154004 |
| ORC4 | origin recognition complex, subunit 4 | 0.0153779 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0152744 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0150713 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0150161 |
| RAB18 | RAB18, member RAS oncogene family | 0.0149637 |
| SPOPL | speckle-type POZ protein-like | 0.0149069 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0147898 |
| SECISBP2L | SECIS binding protein 2-like | 0.0147099 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0145217 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0144787 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0144511 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.014445 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0144064 |
| FMR1 | fragile X mental retardation 1 | 0.0142775 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.014225 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0141424 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0140928 |
| OGA | O-GlcNAcase | 0.0139056 |
| SRP54 | signal recognition particle 54kDa | 0.0139011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | -0.142069 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107989 |
| BCL2L1 | BCL2-like 1 | -0.0980932 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0896765 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0857129 |
| EHBP1 | EH domain binding protein 1 | -0.0850898 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0813696 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0798726 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0796508 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0788341 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0688898 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0641963 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0605552 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0603244 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0578578 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0569624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0560718 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0557202 |
| RPS21 | ribosomal protein S21 | -0.0555757 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0540611 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0535052 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.051466 |
| CADPS | Ca++-dependent secretion activator | -0.0504342 |
| PLSCR1 | phospholipid scramblase 1 | -0.0497152 |
| NEBL | nebulette | -0.0486178 |
| EXOC4 | exocyst complex component 4 | -0.0485971 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0480698 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0478674 |
| AHNAK | AHNAK nucleoprotein | -0.0468409 |
| MX2 | MX dynamin-like GTPase 2 | -0.0460665 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0457361 |
| KRT8 | keratin 8, type II | -0.0455036 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0452152 |
| CUX1 | cut-like homeobox 1 | -0.0449814 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0444657 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0439061 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0417232 |
| RPS6 | ribosomal protein S6 | -0.0411128 |
| FNDC3B | fibronectin type III domain containing 3B | -0.040948 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0409068 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0407862 |
| EGR1 | early growth response 1 | -0.0407625 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0406943 |
| CCND1 | cyclin D1 | -0.0406838 |
| OXSR1 | oxidative stress responsive 1 | -0.0406723 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0392388 |
| ETV6 | ets variant 6 | -0.0390342 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0378499 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.037558 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0373858 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0368464 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0361255 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0357206 |
| USP34 | ubiquitin specific peptidase 34 | -0.0354562 |
| MYO1E | myosin IE | -0.0344535 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0337743 |
| NFIA | nuclear factor I/A | -0.0336755 |
| CD2AP | CD2-associated protein | -0.0334804 |
| EZR | ezrin | -0.033198 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0331704 |
| PKP4 | plakophilin 4 | -0.03287 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0321212 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0319387 |
| RUNX1 | runt-related transcription factor 1 | -0.0318316 |
| TMEM123 | transmembrane protein 123 | -0.0316615 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0316574 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0316124 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0315537 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0309057 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0307135 |
| RIGI | RNA sensor RIG-I | -0.0307128 |
| TPM4 | tropomyosin 4 | -0.0305203 |
| NRP1 | neuropilin 1 | -0.030519 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0303655 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0303116 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0302953 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0301196 |
| DIAPH2 | diaphanous-related formin 2 | -0.0300674 |
| RAD51B | RAD51 paralog B | -0.0298896 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0295972 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0289112 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0287719 |
| ZNRF3 | zinc and ring finger 3 | -0.0286738 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0286101 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0285865 |
| RNF213 | ring finger protein 213 | -0.0285001 |
| SVIL | supervillin | -0.0284554 |
| PHF14 | PHD finger protein 14 | -0.0281002 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0278208 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0277448 |
| SP100 | SP100 nuclear antigen | -0.0274637 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0274148 |
| FAT1 | FAT atypical cadherin 1 | -0.0270278 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.027004 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0264672 |
| PERP | PERP, TP53 apoptosis effector | -0.026404 |
| FMN1 | formin 1 | -0.0262783 |
| FUS | FUS RNA binding protein | -0.0261979 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0259769 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0259394 |
