| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.173164 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.123052 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.112948 |
| PGK1 | phosphoglycerate kinase 1 | 0.111152 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.105273 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0976954 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0946876 |
| PLEC | plectin | 0.0897314 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0889272 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0875117 |
| ANLN | anillin, actin binding protein | 0.0855657 |
| KRT18 | keratin 18, type I | 0.0845951 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0824694 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0728071 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0708567 |
| DSPP | dentin sialophosphoprotein | 0.0704964 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0656554 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0651864 |
| ENO1 | enolase 1, (alpha) | 0.0636519 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0631153 |
| ZNF292 | zinc finger protein 292 | 0.0631009 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.062594 |
| ITGA6 | integrin, alpha 6 | 0.0623558 |
| SET | SET nuclear proto-oncogene | 0.0620258 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0594967 |
| KRT8 | keratin 8, type II | 0.0575579 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0559592 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0546743 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0541052 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0532889 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0531445 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0527216 |
| GOLGA4 | golgin A4 | 0.0523532 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0517645 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0514514 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0503913 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0495148 |
| RPL3 | ribosomal protein L3 | 0.0494823 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0493182 |
| HELZ | helicase with zinc finger | 0.046684 |
| NUP58 | nucleoporin 58 | 0.0466168 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0465873 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0465236 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0463701 |
| LDHA | lactate dehydrogenase A | 0.0454515 |
| KIZ | kizuna centrosomal protein | 0.0453566 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0452049 |
| ASPH | aspartate beta-hydroxylase | 0.044026 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0437948 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0436491 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0429728 |
| ETNK1 | ethanolamine kinase 1 | 0.0427268 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0421181 |
| FNIP1 | folliculin interacting protein 1 | 0.0415607 |
| YEATS2 | YEATS domain containing 2 | 0.0414366 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0411425 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0397029 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0394235 |
| PKM | pyruvate kinase, muscle | 0.0393971 |
| XPO1 | exportin 1 | 0.039059 |
| OGA | O-GlcNAcase | 0.0373858 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0372928 |
| TMF1 | TATA element modulatory factor 1 | 0.036105 |
| PRPF8 | pre-mRNA processing factor 8 | 0.035882 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0356952 |
| COPA | coatomer protein complex, subunit alpha | 0.0354411 |
| MKI67 | marker of proliferation Ki-67 | 0.035326 |
| SPAG9 | sperm associated antigen 9 | 0.0351304 |
| INSIG2 | insulin induced gene 2 | 0.0350647 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0350209 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.034804 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0345264 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0344717 |
| RBM26 | RNA binding motif protein 26 | 0.0343905 |
| ABHD2 | abhydrolase domain containing 2 | 0.0342008 |
| AFDN | afadin, adherens junction formation factor | 0.0340806 |
| MSN | moesin | 0.0338658 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0338235 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0332936 |
| PRELID2 | PRELI domain containing 2 | 0.0332904 |
| TPM3 | tropomyosin 3 | 0.0332803 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0329804 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0329679 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.032944 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0328796 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0325969 |
| FLNA | filamin A, alpha | 0.0322787 |
| USP34 | ubiquitin specific peptidase 34 | 0.0322268 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0321128 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0320725 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0320343 |
| RPL4 | ribosomal protein L4 | 0.0319096 |
| ZNF638 | zinc finger protein 638 | 0.0317056 |
| TPI1 | triosephosphate isomerase 1 | 0.0312909 |
| NCKAP1 | NCK-associated protein 1 | 0.0312106 |
| DIAPH3 | diaphanous-related formin 3 | 0.0311445 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0310776 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0308548 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0307717 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0302599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.177701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153885 |
| SYT1 | synaptotagmin I | -0.0861896 |
| RPS6 | ribosomal protein S6 | -0.0719379 |
| EGR1 | early growth response 1 | -0.0673344 |
| TMSB10 | thymosin beta 10 | -0.0671148 |
| RPL35A | ribosomal protein L35a | -0.0666993 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0602732 |
| CDH13 | cadherin 13 | -0.056185 |
| CDK6 | cyclin-dependent kinase 6 | -0.0529149 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.050079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0497978 |
| CCND1 | cyclin D1 | -0.0483555 |
| RPS24 | ribosomal protein S24 | -0.0460733 |
| SPATA13 | spermatogenesis associated 13 | -0.0431002 |
| TNS3 | tensin 3 | -0.0421639 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0421366 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0417282 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0410427 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0404912 |
| MT2A | metallothionein 2A | -0.0394543 |
| POTEF | POTE ankyrin domain family, member F | -0.039306 |
| RPS19 | ribosomal protein S19 | -0.0391888 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0390107 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0351423 |
| HMGB1 | high mobility group box 1 | -0.0338488 |
| RPS23 | ribosomal protein S23 | -0.032781 |
| RPS13 | ribosomal protein S13 | -0.0311536 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.031131 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0309536 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0308954 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0306491 |
| RPS21 | ribosomal protein S21 | -0.0304596 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299422 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0298253 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0294923 |
| SLC38A2 | solute carrier family 38, member 2 | -0.029458 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0289616 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0284517 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0280233 |
| RPLP2 | ribosomal protein, large, P2 | -0.0279047 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0271971 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0268845 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0268023 |
| BCL2L1 | BCL2-like 1 | -0.0259595 |
| HMGA1 | high mobility group AT-hook 1 | -0.0254821 |
| TMEM123 | transmembrane protein 123 | -0.0254281 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0253822 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.025292 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0248261 |
| FTL | ferritin, light polypeptide | -0.0248 |
| PHF14 | PHD finger protein 14 | -0.0244577 |
| ACTG1 | actin gamma 1 | -0.0239364 |
| RUNX1 | runt-related transcription factor 1 | -0.0239214 |
| WWOX | WW domain containing oxidoreductase | -0.0237119 |
| AK1 | adenylate kinase 1 | -0.023579 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0235442 |
| GPHN | gephyrin | -0.0235113 |
| NOP56 | NOP56 ribonucleoprotein | -0.0234582 |
| RPL12 | ribosomal protein L12 | -0.0232899 |
| RPL38 | ribosomal protein L38 | -0.0228373 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0227762 |
| RPL28 | ribosomal protein L28 | -0.0227404 |
| RPS15 | ribosomal protein S15 | -0.0226223 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0225258 |
| INTS6 | integrator complex subunit 6 | -0.0222187 |
| SYK | spleen tyrosine kinase | -0.0220612 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0219926 |
| RPL34 | ribosomal protein L34 | -0.0219159 |
| BPTF | bromodomain PHD finger transcription factor | -0.0217352 |
| FUS | FUS RNA binding protein | -0.0216168 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0212412 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.02123 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0212219 |
| MTAP | methylthioadenosine phosphorylase | -0.0210997 |
| RPL32 | ribosomal protein L32 | -0.0210578 |
| COBL | cordon-bleu WH2 repeat protein | -0.0210003 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0208599 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0205424 |
| DEK | DEK proto-oncogene | -0.0204651 |
| RBMX | RNA binding motif protein, X-linked | -0.0203908 |
| RPLP0 | ribosomal protein, large, P0 | -0.0202912 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.020059 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.020017 |
| AHI1 | Abelson helper integration site 1 | -0.019905 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0194641 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0193837 |
| FOXQ1 | forkhead box Q1 | -0.0190176 |
| RPL36A | ribosomal protein L36a | -0.0190137 |
| H3-3B | H3.3 histone B | -0.0189503 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0189016 |
| RPS11 | ribosomal protein S11 | -0.0188028 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0187578 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0187068 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0181937 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0181717 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0179728 |
| FRMD5 | FERM domain containing 5 | -0.0179712 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0179351 |
| TULP4 | tubby like protein 4 | -0.0174728 |
